Melvin J. Fregly Papers - UF Special and Area Studies Collections

Melvin J. Fregly Papers - Contents List Continued

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This series includes materials related to Fregly's research of cold, altitude, and cold-induced hypertension. The folders in this series were filed separately from the other research files in this collection and each folder was labeled as a "Cold" file. It should be noted, however, that additional cold research files can be found in the other series in this collection. The majority of the files in this series pertain to a sequence of numbered experiments conducted by Fregly and his assistants.

Box 31

Activity in Cold for Normal and PTU Treated Rats. 1959

Cold Adaptation - Dose Response Study. 1979

Cold and Altitude Experiment 3-4. 1969

Cold and Altitude Experiment 5. 1970-1973

Cold and Altitude Experiment 5 (Fecal Na and K). Circa 1972

Cold and Altitude Experiment 6. 1972

Cold and Altitude Experiment 6. 1973

Cold and Altitude Experiment 7 (Food Analysis). 1972

Cold and Altitude Experiment 7. 1973

Cold and Altitude Experiment 8. 1973

Cold and Altitude Experiment 9. 1973

Cold and Altitude Experiment 9. 1973-1974

Cold and Altitude Experiment 9 (Feces Digestion). 1973

Cold and Altitude Experiments (Food vs. Water Intake and Urine vs. Water Intake). 1970

Cold and Altitude Experiments (Organ vs. Body Weights). 1972-1973

Cold and Altitude Experiments (Osmolarity and Dehydration). 1969-1970

Cold and Altitude Experiments (Plasma and Urinary Osmolarity). 1972

Cold and Altitude Experiments (Series I-II). 1951

Cold and Altitude Experiments (Series III). 1951

Cold and Altitude Experiments (Serum and Dehydration Urine Osmolarity). 1969-1974

Cold and Altitude Experiments (Sodium and Potassium Balance) (1). 1973

Cold and Altitude Experiments (Sodium and Potassium Balance) (2). 1972

Cold and Altitude Experiments (Sodium and Potassium Balance) (3). Circa 1972

Cold and Altitude Experiments (Water Intake vs. Food Intake). 1965-1988

Box 32

Cold Blood Pressure Study. 1981-1982

Cold Blood Pressure Study. 1983-1985

Cold Experiment #1 (Pilot Cold Study). 1986

Cold Experiment #1 (Response to Phenylephrine Isoproterenol and AII). 1987-1993

Cold Experiment #2 (Includes Data on Experiments 3 and 6). 1988-1989

Cold Experiment #3. 1988

Cold Experiment #3 (Urine Na and K). 1988-1989

Cold Experiment #6. 1988

Cold Experiment #7 (Organ and Body Weight, Tail, Blood Pressure). 1988

Cold Experiment #8 (Organ Weights - Rats). 1988

Cold Experiment #10 (K and Na in Urine). 1989

Cold Experiment #11 (Creatinine, K and Na Readings). 1989

Cold Experiment #12 (Direct Blood Pressure Data - Systolic, Diastolic, Mean). 1989

Cold Experiment #13 (Blood Pressure Calculated Data - Systolic, Diastolic, Mean). 1989

Cold Experiment #14 (Body Weight, Blood Pressure and Intake of Water, Food). 1989

Cold Experiment #15 (Cats - Water, NaCl, Food Intake). 1989-1991

Cold Experiment #15 (Raw Data - Indirect Blood Pressure). 1989-1990

Cold Experiment #15 (Indirect Tail Blood Pressure). 1989

Cold Experiment #16 (Catecholamine Outputs). 1990

Cold Experiment #16 (Catecholamine Outputs). 1989-1991

Cold Experiment #16 (Change in Food Intake Due to Cold). 1989

Cold Experiment #16 (P and Na Outputs, Food and Water Intakes). 1989-1990

Cold Experiment #16 (Post-Cold Intake and Output). 1989

Cold Experiment #17. 1989

Box 33

Cold Experiment #19 (Creatinine Readings). 1989

Cold Experiment #22 (Creatinine). 1990-1991

Cold Experiment #25 (Creatinine). 1990-1991

Cold Experiment #27 (Creatinine). 1990

Cold Experiment #28 (Creatinine). 1990-1991

Cold Experiment #30 (DUP and AII Cold Study). 1990-1991

Cold Experiment #30 (DUP and AII Cold Study). 1990-1992

Cold Experiment #31 (Catecholamines in Organs). 1991

Cold Experiment #31 (Urinary Catecholamines). 1991

Cold Experiment #33 (Prazosin). 1992

Cold Experiment #34 (ATZ) (1). 1991-1994

Cold Experiment #34 (ATZ) (2). 1991-1992

Cold Experiment #34 (ATZ) (3). 1991-1992

Cold Experiment #34 (ATZ) (4). 1991-1992

Cold Experiment #34 (ATZ) (5). 1991-1992

Cold Experiment #34 (ATZ) (6). 1991-1992

Cold Experiment #35. 1990-1992

Box 34

Cold Experiment #40. 1991-1992

Cold Experiment #41 (DOCA Salt Niacinamide). 1991-1992

Cold Experiment #103 (AII, Prazosin, L-Arginine). 1991-1992

Cold Experiment #105 (Creatinine). 1992

Cold Experiment #106 (Cold Study Uphill). 1993

Cold Experiment #109 (Urinary Electrolytes from Control, Cold and Warm Sessions). 1993

Cold Experiment #109 (Urinary Catecholamines from Cold Session). 1993

Cold Experiment #109 (Urinary Catecholamines from Control and Warm Sessions). 1993

Cold Experiment #109-2 (Cold, Food Intake). 1993-1994

Cold Experiment #109-2 (Losartan Study). 1994

Cold Experiment #110 (Renal Denervation). 1993

Cold Experiment #110 (Urinary Electrolytes). 1993

Cold Experiment #112 (Renal Denervation). 1993

Cold Experiment #112 (Urinary Electrolytes). 1993-1994

Cold Experiment #117. 1992-1995

Cold Experiment #117 (Effect of Treatment with Pyridoxamine and Sulfaminouracil on Development of DOCA-Induced Hypertension). 1994

Cold Experiments. 1959

Box 35

Cold Experiments. 1958

Cold Exposure. 1973-1974

Cold Hypertension. Not Dated

Colonic Cooling Rates - PTU, Adx and Skin Cooling Rates. 1956

Colonic Cooling Rates - Cortisone, Thyroxine. 1954-1956

Compiled Studies on Cold-Warm. 1994

Cooling Rate and Ca Excretion in Cold. 1978

Cooling Rates - Reserpine. 1957-1959

Deacclimatization Tests. 1951

Decrease in Isoproterenol Sensitivity. 1976

Effect of Cold on Urinary Concentrating Ability of White Rats. 1967-1971

Effect of Low Bulk Diet on Water and Electrolytes. 1967-1970

Effect on Cooling Rate of Exposure to Cold (Every Other Day for Five Exposures). 1951

Evaporative Water Loss. 1953

Food Intake and Urine Osmolarity. 1977

Isoproterenol and Renin Sensitivity in Male and Female Rats. 1975-1976

L-Arginine. 1992

Oxygen Consumption at Cold (5 Degrees C) for PTU vs. Normal Rats. 1959

Repeated Exposures to Cold. 1951

Repeated Exposures to Cold (Every Second Day). 1951

Skin Cooling Tests - Normal, Adx, PTU. 1957-1959

Statistical Analysis Experiment 2 (Cold - Hypertension). Not Dated

Study of Rat Vitals During Exposure to Cold. 1952-1958

Box 36

Summary of Cold Experiments #1. 1991-1992

Summary of Cold Experiments #2. 1990-1993

Summary of Cold Experiments #3. 1990-1993

Summary of Cold Experiments #4. 1990-1993

T-Tests Hypertension Cold Experiment. Not Dated

Test - Aldosterone. 1957

Water and Electrolytes During Cold. 1965-1975

Research Notebooks 1952-1956

Notebooks containing research data and notes related to experiments concerning altitude exposure, cold and hypertension, pregnancy, and the intake of sodium, water, and potassium.

Box 37

Altitude Book I. 1954

Altitude Book II. 1954

Continuous Exposure to Altitude (18,000 feet) Experiment III. 1955

Continuous Exposure to Altitude (18,000 feet) Experiment IV. 1955

Altitude Book Experiment V - Continuous Exposure. 1956

Experiment 2 - Effect of Cold on Hypertensive Rats. 1952

Experiment 2A, 2B, 2C, 2D, 2E, 2G, 2H, 2I (Activity Cages). 1952-1953

Experiment 7. 1954-1955

KCl Intakes (Na2SO4). 1955-1956

Na Free Diet and Measured Amount of Urea and Na and Water Intake in Hypertensive and Normal Rats. 1956

Pregnancy Study. 1954

Pregnancy Studies - Group J. 1954

Research Recording Charts (Heart Rate, Temperature, etc.) 1972-1986

Charts used to record blood pressure, heart rate, temperature, and other data during experiments pertaining to cold and altitude, ATZ, and tryptophan.

Box 38

ATZ Rats. 1975

ATZ Study - Blood Pressure and Heart Rate (8 chart bundles). 1974

ATZ Study - Heart Rate (2 chart bundles). 1975

Cold-Altitude Experiment (5 chart bundles). 1972

Cold-Altitude Study #7 (4 chart bundles). 1972

Cold-Altitude Study #8. 1973

Cold-Altitude Study #9 - Heart Rates. 1973

DOPA - Nicotinic Acid (2 chart bundles). 1986

EB Study (4 chart bundles). 1984

T4 Cholesterol (2 chart bundles). 1973

T4 Implant Study (Rats - ATZ) (2 chart bundles). 1973

Tail Temperature - Heart Rates (8 chart bundles). 1974

Tryptophan. 1986

Research Grants 1952-1998

This series is comprised of files pertaining to grant-funded research conducted or proposed by Fregly. The files contain grant applications, status reports, financial records, and correspondence related to the research projects. Topics include hypertension, the thyroid, oral contraceptives, salt preference and appetite, thirst and drinking, altitude and cold, and water and electrolyte exchange during exposure to cold.

Box 39

Adrenal Gland - Renal Hypertension. 1956-1959

Application for Training (Institutional Division of Genetic, Endocrinology and Metabolism). 1974-1979

Application - Brain Mechanisms of Drinking. 1986

Application - Brain Mechanisms of Drinking. 1986-1988

Application - Influence of Early Salt Diet on Taste and Blood Pressure. 1994

Application - Oral Contraceptive and Hypertension. 1971-1982

Application - Thermogenic Drinking in Cold-Adapted Rats. 1983-1985

Applications/Extensions - Oral Contraceptive. 1977-1982

Bio-Behavioral Aspects of Salt Appetite. 1985-1989

Bio-Behavioral Aspects of Salt Appetite. 1985-1987

Bio-Behavioral Aspects of Salt Appetite. 1986

Cardiovascular Research Training Grant. 1977-1978

Diuretics in Renal Iodide Excretion (Folder 1 of 2). 1966-1971

Diuretics in Renal Iodide Excretion (Folder 2 of 2). 1966-1971

Effect of Tyrosine on the Development of Hypertension. 1981-1989

Effect of Tyrosine on the Development of Hypertension. 1981-1986

Effect of Tyrosine on the Development of Hypertension. 1984-1988

Hormones, Neurotransmitters and Receptors in Cold and Heat. 1985-1986

Hypothalamic Pituitary Response to Stress (Includes Articles by Other Authors). 1952-1987

Box 40

Metabolic Responses to the Stress of Oxygen at High Pressure. 1968-1972

National Science Foundation (Includes Research Proposal - Water and Sodium Intake). 1958-1959

Office of Naval Research (Includes Statements and Research Proposal - Post-Cold Drinking Phenomenon). 1969-1971

Office of Naval Research (Includes Invoice Statements and Research Proposal - Water and Electrolyte During Exposure to Cold and Altitude). 1966-1973

Oral Contraceptives and Hypertension. 1980-1984

Physiological Responses to Chronic Cold Exposure. 1986-1992

Physiological Responses to Chronic Cold Exposure. 1986

Physiological Responses to Chronic Cold Exposure. 1987-1998

Post-Cold Drinking Phenomenon in Rats. 1964-1965

Post-Cold Drinking Phenomenon in Rats (Folder 1 of 2). 1964-1969

Post-Cold Drinking Phenomenon in Rats (Folder 2 of 2). 1964-1969

Regulation of NaCl Intake by Rats. 1988-1989

Regulation of Sodium Intake by Hypertensive Rats. 1958

Regulation of the Brain Renin Angiotensin System. 1985-1986

Renal-Thyroid Interrelationship in Hypertension. 1972-1976

Renal-Thyroid Interrelationship in Hypertension. 1981-1985

Research Proposal - Oral Contraceptives and Hypertension (National Science Foundation). 1971

Role of Hydration and Hyperhydration. 1990-1992

Role of Thyroid in Hypertension. 1970-1973

Box 41

Role of Thyroid in Hypertension (Folder 1 of 2). 1960-1972

Role of Thyroid in Hypertension (Folder 2 of 2). 1960-1972

Salt Appetite (Folder 1 of 2). 1968-1971

Salt Appetite (Folder 2 of 2). 1968-1971

Stress, Sodium and Blood Pressure Regulation. 1987

Sulfur Compounds. 1962-1966

Thermogenic Drinking in Cold-Adapted Rats. 1982-1984

Thermogenic Drinking in Cold-Adapted Rats. 1980-1983

Thermogenic Drinking in Cold-Adapted Rats. 1980-1981

Water and Electrolyte Exchange During Exposure to Cold. 1972-1978

Water and Electrolyte Exchange During Exposure to Cold. 1974-1981

Water and Electrolyte Exchange During Exposure to Cold. 1968-1986

Water and Electrolyte Exchange During Exposure to Cold. 1983-1992

Water and Electrolyte Exchange During Exposure to Cold. 1986-1991

Water and Electrolyte Exchange During Exposure to Cold. 1987-1993

Water and Electrolyte Exchange During Exposure to Cold. 1989-1992

Water and Electrolyte Exchange During Exposure to Cold and Altitude (Folder 1 of 3). 1973-1983

Water and Electrolyte Exchange During Exposure to Cold and Altitude (Folder 2 of 3). 1973-1983

Water and Electrolyte Exchange During Exposure to Cold and Altitude (Folder 3 of 3). 1973-1983

Notes 1947-1976

This small series contains notes written by Fregly on topics such as hypertension, salt appetite, thirst, the thyroid, hormones, and general physiology. A few files contain Fregly's notes taken as a student in biochemistry, biology, and chemistry classes.

Box 42

Biochemistry 200. 1950-1951

Biology 203. 1947-1948

Chemistry 115. 1947

DDD Studies (Includes Correspondence). 1954-1965

Dopamine - Drinking. Not Dated

Early Concepts of Physiological Regulations (Dr. Edward F. Adolph). 1972

Electrical Fundamentals. 1964

General Notes, Primarily on Hormones. Not Dated

Growth Hormone. Not Dated

Hypertension. Not Dated

Kinnis, Kallekrein, Prostaglandins. Not Dated

Salt Appetite. Not Dated

Salt in the Human Body. 1962

Spontaneous Running Activity. Not Dated

Thirst Analog Models. 1957-1976

Thyroid and Altitude. Not Dated

Thyroid and Heat. Not Dated

Thyroid and Hypertension. Not Dated

Visualization of Cortical vs. Medullary Blood Flow. 1974

VO2 Apparatus. Not Dated

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Melvin J. Fregly Papers - Contents List Continued

Contents List

Cold Research 1951-1995

Research Notebooks 1952-1956

Research Recording Charts (Heart Rate, Temperature, etc.) 1972-1986

Research Grants 1952-1998

Notes 1947-1976