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Research Files 1941-1996
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Materials related to Fregly's research, including experiment methodology, data, notes,
conclusions, and preliminary writings describing results. The files represent all of
his areas of research, including hypertension (high blood pressure), body temperature
regulation, behavior, and fluid and electrolyte balance. Frequent topics include the
thyroid, tryptophan, catecholamines, propylthiouracil (PTU), oral contraceptives, salt
preference and appetite, the adrenal gland, aldosterone, angiotensin II (AII),
hydrochlorothiazide (HCZ), thirst and drinking, thyroid depressing factor (TDF),
altitude and cold, hypothyroidism, isoproterenol, DOCA-salt, running activity,
aminotriazole (ATZ), enovid, hypoxia, captopril, and nicotinic acid.
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It should be noted that this Research Files series does not include all materials
related to Fregly's research. For example, the collection also includes a series
pertaining to his Cold Research, the Research Notebooks series, the Research Recording
Charts series, and the Research Grants series. Further, the writings used to report
the results of research studies are found in Publications and Writings series.
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Box 4 |
2-Methoxyphenyl Piperazine Data. 1987
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5-HTP Renal Hypertension Pyridoxine HCL and Tryptophan. 1988-1989 |
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5-HTP - Urinary Catecholamines. 1982 |
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Acetylchlorothiazide Experiment 1. 1963 |
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Acetylchlorothiazide Experiment 2. 1963 |
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Acetylchlorothiazide Experiment 3. 1963-1964 |
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Activity Experiment - Oral Contraceptives. 1967-1969 |
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Activity of TDF Fractions, Effect of Varying Lactoperoxidase Concentration. 1975 |
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Activity-PTU Experiment 1. 1958 |
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Activity-PTU Experiment 3. 1958 |
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Activity Study - Serotonin. 1980 |
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Adrenal Cholesterol. 1956-1957 |
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Adrenalectomized Rats. 1973-1974 |
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Adrenalectomized Study (Rats). 1987 |
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Adrenalectomized Study (Rats). 1987 |
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Adrenalectomized Study (Rats). 1987 |
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Adrenalectomy. 1959 |
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Adrenalectomy. 1987-1988 |
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Adrenalectomy - Aldosterone Diuresis. 1969 |
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Adrex, Angiotensin, Aldosterone. 1964 |
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Adrex - Angiotensin (LITT) #1. Not Dated |
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Adrex Diuresis Experiments (1). 1965 |
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Adrex Diuresis Experiments (2). 1966 |
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Adrex Diuresis Experiments (3). 1968-1969 |
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Adrex - DOCA Experiment #2. 1966 |
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Adrex Experiments. 1979 |
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Adrex - NaCl Appetite (Effects of Corticosterone, DOCA and Testosterone). 1964 |
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Adrex - Rats on Salt Solution. 1958 |
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Adrex - Salt Appetite. 1957 |
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Adrex - Salt Hypertension Experiment 2. 1958 |
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Adx and Adx Encapsulated. 1958 |
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Adx Encap Experiment 3. 1957 |
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Adx Encap Experiment 3. 1957-1958 |
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AII (Angiotensin II) and DUP 753 Study. 1991-1992 |
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AII (Angiotensin II) and Glucose Loads Study. 1992 |
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AII (Angiotensin II) and Isoproterenol. 1993 |
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AII (Angiotensin II) and Isoproterenol on EB Rats. 1984-1985 |
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AII (Angiotensin II) and NaCl Study on Rats. 1992 |
Box 5 |
AII (Angiotensin II) and NaCl Study. 1992
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AII (Angiotensin II) and UK Drink Study. 1987-1988 |
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AII (Angiotensin II) and V-Blocker. 1990 |
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AII (Angiotensin II), ANF and TDF Drink. 1985 |
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AII (Angiotensin II) on DOCA Study. 1992 |
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AII (Angiotensin II) with Varied Concentration of NaCl to Drink. 1992 |
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Alcohol Diuresis. 1965-1966 |
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Aldactone on Enovid Salt Appetite. 1972-1973 |
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Aldosterone, DOCA, Angiotensin Effect on NaCl Appetite of Adrex Rats. 1963 |
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Aldosterone Experiment 2 and CoCl2 Experiment. 1963 |
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Aldosterone - Experiment on Aldosterone Treated Rats. 1957-1959 |
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Aldosterone Hypertension Experiment. 1967 |
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Aldosterone Secretion and NaCl Intake. 1963-1967 |
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Aldosterone Secretion Rate and NaCl Intake. 1963-1964 |
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Altitude Cold Experiments #1-3. 1968-1969 |
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Altitude Cold Experiments #4-5. 1969-1970 |
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Altitude Cold Experiments #6. 1972 |
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Altitude Cold Experiments #8. 1973 |
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Altitude Cold Experiments #9. 1973-1977 |
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Altitude - Cold Experiments Series I. 1951 |
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Altitude - Cold Experiments Series II. 1951 |
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Altitude - Cold Experiments Series III-IV. 1951-1952 |
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Altitude - Cold Experiments Series V. 1952 |
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Altitude Experiment. 1964-1966 |
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Altitude Experiment #1. 1965-1968 |
Box 6 |
Altitude Experiment #2 (12% Oxygen). 1965-1968
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Altitude Experiment (15% Oxygen). 1964-1966 |
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Altitude Experiment (16% Oxygen). 1967-1970 |
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Altitude Experiment (17% Oxygen). 1966 |
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Altitude Experiment (Completed Analyses). 1964-1966 |
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Altitude Experiment - Data. 1964 |
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Altitude Experiment - Hypertensive Rats. Not Dated |
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Altitude Experiment - Hypoxia on Blood Pressure and Thyroid Function. 1961-1965 |
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Altitude Experiments. 1955-1956 |
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Altitude Experiments #1-3. 1960-1961 |
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Altitude Experiments #4. 1961-1966 |
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Altitude Experiments #I. 1954-1955 |
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Altitude Experiments (Urine, Feces, and Osmolarity). 1964 |
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Amino Acids and TDF Analysis. 1984-1986 |
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Aminophylline Dopamine Blockers. Not Dated |
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Aminotriazole and Hypertension. 1966-1968 |
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Angiotensin Autoradiography. Circa 1984-1987 |
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Angiotensin II and Creatinine Study. 1977-1984 |
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Angiotensin II Drink - Bromocriptine and Dopamine. 1984-1988 |
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Angiotensin II Drink - Bromocriptine and Dopamine. 1980-1984 |
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Angiotensin Induced Drinking (Spiperone, Atropine). 1984-1988 |
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Angiotensin - LITT #2. 1965 |
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Angiotensin - Pitressin Adrex Rats. 1963 |
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Anthranilic Acid - DOCA Experiment. 1991-1992 |
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Antihypertensive Agent - Aldomet. 1962-1963 |
Box 7 |
Arginine Study on Rat Colonic and Tail Skin Temperature. 1992-1993
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Atenolol on Isoproterenol Drink. 1980 |
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Atropine and Bethanechol. 1980-1982 |
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ATZ (Aminotriazole). 1966-1967 |
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ATZ Effect - Acute Diet vs. I.T. 1972 |
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ATZ Experiment 1. 1967 |
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ATZ Experiment 2. 1967 |
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ATZ Hypertension. 1967 |
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ATZ - Second Study. 1974 |
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ATZ - Single Injection (I131). 1967 |
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ATZ Study #3. 1971-1975 |
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B-Adrenoceptor Subtype Mediating Tail Skin Temperature of Rats. 1977-1982 |
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B-Estradiol 3-Benzoate. 1988 |
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Balance Study (Adrex and Normal Rats Given Enovid). 1973-1974 |
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Balance Study (Cook). 1957 |
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Balance Study (Normal Rats Given Mestranol and Norethynodrel). 1973-1974 |
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Balance Study on Normal Male Rats (Norethynodrel and Mestranol). 1974 |
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Benserazide-Isoproterenol Study. 1978-1980 |
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Benzyl Sulfamic Acid Experiment. 1963 |
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Bethanechol - BP Study. 1981 |
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Blood Pressure - EB Treated Rats. Not Dated |
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Blood Pressure - EB Treated Rats. Not Dated |
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Blood Pressure - EB Treated Rats. Not Dated |
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Blood Pressure - EB Treated Rats. Not Dated |
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Blood Pressure - Norethynodrel and Ethynyl Estradiol. 1971-1972 |
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Blood Pressure of Aldosterone-Treated Rats. Not Dated |
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Blood Pressure Response of Rats Treated with 733-64A. 1966 |
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Blood Pressure Studies (Systolic). 1959 |
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Blood Pressure Study (6-HMP, 5-CHMP). 1965-1967 |
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Blood Volume Dialysis (Includes Journal Articles). 1947-1966 |
Box 8 |
Bradykinin, DUP and Captopril. 1992-1993
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Bromocriptine on Individual Drinking. 1983-1984 |
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Calcium-Encap Study 1. 1984 |
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Calcium-Encap Study 2. 1984 |
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Calcium-Encap Study 3. 1986-1988 |
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Calcium-Serum Study. 1968 |
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Calcium Study on Rats. 1991 |
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Calcium Study - Renal Encapsulated. 1985 |
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Calcium Study - Renal Encapsulated. 1985 |
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Calcium Study - Renal Encapsulated. 1985 |
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Calcium-Tryptophan Diet Study. 1989-1994 |
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Calcium-Tryptophan Diet Study. 1994 |
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Calcium-Tryptophan DOCA Hypertension. 1989-1994 |
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Calcium-Tryptophan DOCA Hypertension. 1989-1994 |
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Captopril on NaCl Appetite. 1978-1979 |
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Captopril - Renal Hypertension. 1979 |
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Captopril - Tryptophan Experiments. 1989 |
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Carbethoxy-2-Thiouracil. 1966 |
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Carboxytryptamine Test. 1993 |
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Cardiovascular and Thyroid Hypertension. Not Dated |
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Catecholamine. 1989 |
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Catecholamine Output (Dr. Muther). 1988 |
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Catecholamines on Aortic Smooth Muscles. 1975 |
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Central Administration of Octopamines and Drinking (Folder 1 of 2). 1983-1984 |
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Central Administration of Octopamines and Drinking (Folder 2 of 2). 1983-1984 |
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Central vs. Peripheral AII (Angiotensin II). 1983-1984 |
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Characterization of Blood Pressure vs. Time Mathematically. Not Dated |
Box 9 |
Chronic Estrogen Treatment on Water Exchange (Fahey). 1983-1984
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Chronic Estrogen Treatment on Water Exchange (Fahey). 1983-1984 |
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Clonidine. 1976-1978 |
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Clonidine - Tail Skin Temperature and Heart Rate in Response to Isoproterenol. 1976-1982 |
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Cold Adaptation. 1979 |
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Cold Experiment - Low Bulk Diet (Debby Giles). 1967 |
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Cold Experiment 2. 1988 |
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Cold Experiment 4 (BP Traces). 1988 |
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Cold Experiments - Food, Water Intake and Urine Output. 1965-1966 |
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Cold Experiments - Food, Water Intake and Urine Output. 1965-1968 |
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Cold Experiments (Temperature Measurement). 1960 |
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Cold Exposure for 20 Days (Harvard). 1952 |
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Cold Hypertension Experiments. 1952 |
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Cold Rats - Organ Weight and Blood Pressure. 1977 |
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Combined AII Drink Catecholamines. 1987-1988 |
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Combined AII Drink Catecholamines. 1988 |
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Combined AII Drink Catecholamines. 1988-1989 |
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Comparison Study of KNO3 and KCl with Respect to Blood Pressure. 1960-1961 |
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Compensatory Renal Hypertrophy and Thyroid Activity. 1968-1969 |
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Compound S-615-76. 1965 |
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Computer Fortran Programs. 1969 |
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Contraceptive B - Responses (Thyroid Hormone). 1976-1978 |
Box 10 |
Contractile Substance in Plasma and Urine of Rats. Not Dated
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Control Tube Rats (Tail Skin, Rectal and Air Temperature). 1977 |
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Cooling Rates Experiments. 1958-1959 |
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Cooling Rates of Rats. 1954-1955 |
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Cooling Rates of Rats in Air. 1949-1950 |
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Cooling Rate T4 Tube. 1973 |
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Cooling Tests on Normal and Adx Rats. 1958 |
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Corticosterone Acetate Rats. 1979 |
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Corticosterone Acetate Study. 1978-1979 |
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Corticosterone on Glucose Intake of Hypox Rats. 1966 |
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DA2 - Agonist and Drinking. 1984-1985 |
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DDD and Hooded Rats. 1963-1992 |
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DDD and PAH Excretion. 1967 |
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DDD - Ethionine Experiment. 1966 |
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DDD Experiments - Combined Data (Experiments 3-6). 1962 |
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DDD on Excretion of Radioactive T4 in Bile. Not Dated |
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Dehydration Induced Drinking. 1980-1982 |
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Dehydration - Water, Food Deprivation. 1990 |
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Dehydration - Water, Food Deprivation. 1990 |
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Deoxycorticosterone Acetate Study. 1983-1984 |
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Dexamethasone - Hypox Glucose Experiment. 1966 |
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Diamox - Effect on NHCO3 Intake. 1968 |
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Direct Blood Pressure Experiments. 1962-1965 |
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Direct Blood Pressure Study (Data CA vs. Control). 1983 |
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Direct Blood Pressure Study (Data CA vs. Control). 1979-1983 |
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Diuresis During Alcohol Ingestion. 1963-1966 |
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Diuresis Experiment 1-3. 1966 |
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Diuresis Experiments 722-58. 1966 |
Box 11 |
Diuresis Experiments 722-70, 730-334. 1966
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Diuresis Experiments (Dr. Cooper of Toronto). 1969 |
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Diuresis Experiments Summary S-720-22. 1965-1966 |
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Diuresis Experiments (Water, Urea, KCl, NaCl and Pitressin Diuresis). 1965 |
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Diuresis on Female Blue Spruce Rats Treated with Norethynodrel and Ethynyl Estradiol. 1975 |
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Diuretics and Renal Iodide Excretion by Humans (HCZ and AZ). 1966-1973 |
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Diuril and DOCA Hypertension Experiment 6. 1961-1962 |
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Diuril and Hydrodiuril Experiment 3. 1960-1961 |
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Diuril Experiment 1. 1959-1960 |
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Diuril Experiment 2. 1960 |
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DOCA - Adrex Salt Appetite Experiment (Student Experiment). 1965 |
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DOCA - Adrex Salt Taste Threshold. Circa 1969 |
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DOCA and NaCl Intake (Swartz) Folder 1 of 2. 1964 |
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DOCA and NaCl Intake (Swartz) Folder 2 of 2. 1964 |
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DOCA and Pyridoxal HCL Study. 1988 |
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DOCA and Saline on ANF. 1985-1986 |
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DOCA and Tryptophan. 1982-1986 |
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DOCA - Estrogen Study. 1987 |
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DOCA Males - L-Kynurenine Infusion. 1989-1991 |
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DOCA on Preference Threshold for NaCl. 1967 |
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DOCA on Salt Appetite of Captopril-Treated Rats. 1984-1985 |
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DOCA-Pyridoxal Phosphate Study. 1987 |
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DOCA Rats Study. 1987-1992 |
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DOCA Salt L-5HTP Study (Ora Lockley) Folder 1 of 2. 1985-1986 |
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DOCA Salt L-5HTP Study (Ora Lockley) Folder 2 of 2. 1985-1986 |
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DOCA Salt Tryptophan and Pyridoxal HCL. 1988 |
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DOCA Salt Tryptophan Experiment (41). 1991 |
Box 12 |
DOCA Salt Tryptophan Study (Ora Lockley) Folder 1 of 2. 1986
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DOCA Salt Tryptophan Study (Ora Lockley) Folder 2 of 2. 1986 |
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DOCA Study. 1987-1991 |
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DOCA Tryptophan Folder 1 of 2. 1985 |
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DOCA Tryptophan Folder 2 of 2. 1985 |
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DOCA Tryptophan Folder 1 of 2. 1985 |
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DOCA Tryptophan Folder 2 of 2. 1985 |
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DOCA Tryptophan Study - Angiotensin II. 1985 |
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DOCA Tryptophan Study (Nephrectomy) Folder 1 of 2. 1985 |
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DOCA Tryptophan Study (Nephrectomy) Folder 2 of 2. 1985 |
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DOCA Tube Experiment. 1984 |
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DOCA Tyrosine Experiments. 1985-1986 |
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Dogs - Diuresis (Ethacrynic Acid, Aminophylline, etc.). 1967-1970 |
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Dogs - Drinking (Diuretics). 1966-1968 |
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Dopamine - Blood Pressure. Not Dated |
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Dopamine - Isoproterenol (AII Drinks). 1984-1988 |
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DUP 753. 1990-1991 |
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DUP and Saralasin Study File 1. 1992 |
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DUP and Saralasin Study File 2. 1992 |
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DUP and Saralasin Study File 3. 1992 |
Box 13 |
EB - Animal Data and Tube Data. 1976-1978
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EB DOCA Study on Female Rats. 1989 |
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EB, Lipolysis and Camp Experiments. 1977 |
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Effect of 5,6-Dimethyl-2-Thiouracil on Thyroid Gland. 1966-1967 |
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Effect of 5-Methyl Thiouracil on Thyroid Gland of Rats. 1967 |
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Effect of Acute Administration of Isotonic Saline on Urine Output in Rats on NaCl Free Diet. 1978 |
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Effect of Administration of Haloperidol in Female Rats. 1978-1979 |
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Effect of Administration of Haloperidol on Output and Urinary Electrolyte Excretion in Rats. 1978 |
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Effect of Adrenalectomy and Treatment with Cortisone Acetate (Student Experiments). 1963 |
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Effect of Adrenalectomy and Treatment with Cortisone Acetate (Student Experiments). 1962-1964 |
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Effect of AII on Colonic and Tail Skin Temperature. 1993 |
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Effect of AII and DUP 753 on Colonic and Tail Skin Temperature. 1992-1993 |
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Effect of AII and Isoproterenol on Tail Skin and Colonic Temperature. 1993 |
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Effect of AII and Isoproterenol on Tail Skin and Colonic Temperature. 1993 |
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Effect of Aldosterone on Salt Intake of Adrex Rats. 1964 |
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Effect of Aminotriazole on Thyroxine I131 Metabolism. 1967 |
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Effect of Amphenone B on Blood Pressure and Thyroid Function on Rats. 1959-1960 |
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Effect of Anti-Thyroid Drugs on Development of Hypertension in Adrenalectomized Rats. 1958 |
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Effect of Apomorphine on Rat Water Intake and Urine Output. Not Dated |
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Effect of Atropine on Water Intake Induced by Isoproterenol. 1978-1979 |
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Effect of Butyl-4-Ethyl Sydnone on Rat. 1962 |
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Effect of Carbichol and CCK on Water Intake and Urine Output. 1993 |
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Effect of Chloride-Deficient Diet on Spontaneous Intake of NaCl. 1970 |
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Effect of Chronic Administration of Norethynodrel and Ethynyl Estradiol. 1973 |
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Effect of Chronic Administration of Norethynodrel and Ethynyl Estradiol. 1973 |
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Effect of Chronic Administration of Norethynodrel and Ethynyl Estradiol on Heart Rate and Blood Pressure. 1974 |
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Effect of Chronic Exposure to Cold Hypoxia and Both Combined on Water and Electrolyte Exchange (Includes Journal Articles).
1975-1977
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Effect of Chronic Treatment with Tryptophan. 1986 |
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Effect of Chronic Treatment with Tryptophan. 1978-1987 |
Box 14 |
Effect of Clonidine on Responses to Graded Doses of Pitressin. 1977-1979
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Effect of Clonidine and Naloxone on Angiotensin II Induced Drinking. 1983 |
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Effect of CNS Lesions on Response to ATZ. 1956-1968 |
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Effect of Cold on Hypertensive Rats. 1952 |
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Effect of Cold on I131 Uptake and Release. 1973 |
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Effect of Cold on Oxygen Response to Isoproterenol. 1975 |
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Effect of DDC on Rat Water Intake and Urine Output. 1978-1979 |
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Effect of DDD on Insulin Sensitivity and Adrenal Histology of the Monkey. 1955 |
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Effect of DDD on Sleeping Time. 1968-1969 |
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Effect of Dietary Calcium Supplementation on Blood Pressure. 1984 |
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Effect of Dietary Calcium Supplementation on Blood Pressure. 1984 |
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Effect of Dietary Taurine on Development of DOCA-Salt Induced Hypertension. Circa 1986 |
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Effect of Diuretics on the Rate of Deiodination of I-Thyroxine by Kidney Slices in Vitro. Not Dated |
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Effect of DOCA on NaCl Intake of Normal and Lesioned Rats. 1966 |
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Effect of Enovid on NaCl Intake and Excretion (Adrenalectomized Rats). 1972-1973 |
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Effect of Estradiol in Rats. 1983-1984 |
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Effect of Estrogens on NaCl Intake and Organ Weight of Rats. 1971 |
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Effect of Fluid Intake on PTU-Treated Rats. 1958 |
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Effect of Graded Doses of an Oral Contraceptive on Spontaneous Activity. 1971 |
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Effect of HCZ (Hydrochlorothiazide) on NaHCO3 Intake. Circa 1966 |
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Effect of HCZ (Hydrochlorothiazide) on Spontaneous Intake of Sodium Gluconate. 1968 |
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Effect of Heat Exposure on Fluid Exchange. Not Dated |
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Effect of Hydrochlorothiazide on Salt Intake of Rats. 1966 |
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Effect of Indomethacin on Warm-Adapted Rats. 1976-1985 |
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Effect of Intraperitoneal Load of NaCl Solution. 1976 |
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Effect of Isoproterenol on Oxygen Consumption and Temperature of Rats. 1977-1981 |
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Effect of Isoproterenol on Oxygen Consumption and Temperature of Rats. 1977 |
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Effect of Isoproterenol, Saline and Bradykinin in SQ14225 and Captopril-Treated Rats. 1978 |
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Effect of Isoproterenol, Saline and Bradykinin in SQ14225 and Captopril-Treated Rats. 1978-1979 |
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Effect of Maltose on NaCl Intake. 1984 |
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Effect of Maltose on Preference Threshold of Rats. 1968 |
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Effect of NaHCO3 on Spontaneous Intake of NaCl Solutions in Rats. 1969 |
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Effect of Neuropeptide on Colonic and Tail Skin Temperature. 1993 |
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Effect of Ng/K Ratio of Salt Solution. 1966-1994 |
Box 15 |
Effect of Norethynodrel on Hypertensive Rats. 1972-1973
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Effect of O,P-DDD on Fecal and Urinary Excretion of Radioactivity. 1955-1966 |
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Effect of Parachlorophenylalanine on the Rat. 1978-1979 |
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Effect of Phentolamine and Isoproterenol on Induced Drinking (Estrogen Treated Rats). 1981-1982 |
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Effect of Phenylephrine on Urinary Flow, Na and K Output. 1975-1976 |
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Effect of Prazosin on Angiotensin II Induced Drinking in Female Rats. 1983-1984 |
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Effect of PTU on Organ Weight/Body Weight of PTU Treated, Normal and Hypertensive Rats. 1956-1964 |
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Effect of PTU on Thyroid Weight and Function of Rats. 1967 |
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Effect of Renal Extract on Urine Flow. 1971 |
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Effect of S615-76 on Dogs and Cats. 1964 |
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Effect of Salt on Growth of PTU Treated Rats. 1959-1961 |
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Effect of Sulfaminouracil on the Ratio of Organ Weight to Body Weight. 1963 |
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Effect of Tail Skin Temperature on Response to Isoproterenol. Not Dated |
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Effect of TDF on Frog Skin. 1983-1985 |
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Effect of TDF and Isoproterenol on Water Intake and Urine Output. 1980-1981 |
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Effect of Thyroxin on NaCl Intake of Adrex Rats. 1963 |
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Effect of TRH Upon I131 Update (I). 1973 |
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Effect of TRH Upon I131 Update (II). 1973 |
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Effect of Various Substance Treatment on the Thyroid Gland. 1953-1965 |
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Effects of 2-Thio-6-Aminouracil (Raw Data). 1966-1967 |
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Effects of 2-Thio-6-Aminouracil (Reduced Data). 1966-1967 |
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Effects of 5-Carboxy-2-Thiouracil Experiments. 1966 |
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Effects of Captopril and Bradykinin on Tail Skin and Colonic Temperature. 1994 |
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Effects of Captopril and Bradykinin on Tail Skin and Colonic Temperature. 1994 |
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Effects of Chlorothiazide and Hydrochlorothiazide on Thyroid Weight Ratios. 1958-1965 |
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Effects of Enovid on Blood Pressure of Rats. 1971 |
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Effects of Iproniazid on Action of Reserpine-CCR. 1960 |
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Effects of Varying Concentrations of Resorcinol. 1973-1974 |
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Effects of Water Temperature on Water Intake of Dehydrated Dogs. 1980 |
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Effects of Water Temperature on Drinking in Female Dehydrated Rats. 1975 |
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Efficiency of SC-6584 in Reducing Blood Pressure by Reducing Adrenal Function. 1957-1959 |
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Electrical Recording of Rapidly Occurring Events in Man. Circa 1958 |
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Encap Ca Study. 1985-1989 |
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Encap - Tryptophan and Ca. 1986 |
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Encapsulated Rate Oxygen Consumption. 1959 |
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Enovid-Activity Experiment (NASA Building). 1968-1969 |
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Enovid Balance Study (Adrex Rats). 1972 |
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Enovid Experiment - Testicular Weight (NaCl Intake). 1970-1972 |
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Enovid Female Rats - Salt Specificity Experiments. 1972 |
Box 16 |
Enovid Hypertension. 1970-1971
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Enovid - Hypertension and Salt Appetite (Female Rats). 1970-1972 |
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Enovid - Hypertension Experiment #3. 1970 |
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Enovid - Infusions of Epi Norepi and Angiotensin. 1972 |
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Enovid - Normal Female Rats. 1973-1974 |
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Enovid Running Activity - Ovariectomized Rats. 1969-1970 |
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Enovid Running Experiment. 1970-1971 |
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Enovid Sleeping Time. 1968 |
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Established Hypertensives - Thyroid Cell Height. Not Dated |
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Estradiol Benzoate - Effect on Isoproterenol (Induced Drink). 1976 |
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Estradiol Benzoate Rats. 1977-1978 |
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Estradiol Measurement. 1983-1984 |
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Estrogen - Catecholamines. 1983-1984 |
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Estrogen Hypertension. Not Dated |
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Estrogen T4 and T3. 1977-1979 |
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Estrogen-Treated Isoproterenol Drink. 1979 |
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Estrogen Treated Rats. 1984 |
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Estrone-PTU Experiments. 1963-1964 |
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Ethynyl Estradiol (EE). 1976-1979 |
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Ethynyl Estradiol and Distilled Water on Rats. 1976 |
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Ethynyl Estradiol Tube Rats. 1976 |
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Experiment #105 DOCA Salt Kynurenic Acid Nyacinamide. 1992 |
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Experiment - et 1 oz. AII Drinking. 1992 |
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Experiment on Effect of Sodium Chloride on Metabolic Rate of Rats. 1967 |
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Exposure of Normal Diet and PTU-Treated Rats to Cold. 1960 |
|
Factors Affecting NaCl Intake. 1964-1994 |
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Factors Affecting Spontaneous NaCl Appetite. 1971 |
|
Fat Diet Studies. 1973-1974 |
|
Fat Diet Studies. 1973 |
|
Fat Diet Studies. 1978 |
|
Fat Diet Studies - Summaries. 1974 |
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Fecal and Urinary Thyroxine I131. 1966 |
|
Fecal Experiments 3-4 (Na and K). 1969 |
|
Feces Na and K Concentrations (Cold-Altitude Experiments). 1972-1973 |
|
Fenfluoramine Study. 1986-1987 |
|
Field DDD and Ethionine. 1966 |
|
First Adrex-Aldosterone Experiment (0.1, 0.5, 1.0, and 5 mg). 1963 |
|
Fluid Intakes I131-Treated - Jacobson. 1958 |
|
Glucose Determination. 1974 |
|
Glucose Load Study and AII (File 1). 1992 |
Box 17 |
Glucose Load Study and AII (File 2). 1992
|
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Glucose Load Study and AII (File 3). 1992 |
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Glucose Load Study and AII (File 3 - continued). 1992 |
|
Glucose - NaCl Taste Interaction. 1969 |
|
Glucose - NaCl Taste Interrelationship. 1969 |
|
Glucose Study (Control Rats). 1977 |
|
Glycerol Solution in the Prevention of Hemorrhagic Shock. 1992 |
|
Graded NaCl Intake on Drinking. 1986 |
|
Graphs from Various Experiments. Not Dated |
|
Growth Hormone and Exposure to Cole. 1958-1960 |
|
Growth Hormone Papers. 1956-1958 |
|
Guinea Pigs - Blood Pressure Experiment 1. 1965 |
|
Guinea Pigs - Blood Pressure Experiment 2. 1966-1967 |
|
Guinea Pigs - Blood Pressure Experiment 3 (Thyroxine-Hypertension). 1966-1967 |
|
HCZ (Hydrochlorothiazide) - Taste Threshold. Not Dated |
|
HCZ DOCA Experiment - Adrex Rats. 1966-1985 |
|
HCZ - Effect on NaCl Intake Write Up. 1961-1967 |
|
HCZ Experiment - Sodium Balance. 1966-1967 |
|
HCZ - KCl Intake Experiments. 1966 |
|
HCZ - NaCl Intake Experiments. 1965 |
|
HCZ on Thyroxine I131 Experiment 1. 1965-1967 |
|
HCZ on Thyroxine I131 Experiment 4. 1964-1966 |
|
HCZ on Thyroxine Excretion. Not Dated |
|
Heat Experiments. 1957 |
|
Heat Experiments. 1957-1959 |
|
Heat Experiments (Aldosterone and DOCA). 1957-1959 |
|
Heat Induced Drinking. 1989-1991 |
|
Heat Output and Weight Loss During Fasting in Steroid-Treated Rats. 1974 |
|
Heat Production - Heat Loss Experiments on Maltose Rats. 1974-1976 |
|
Heating Experiments. 1957 |
|
Hibernating Ground Squirrel Study. 1951 |
|
Hibernating Hamster Data. 1951 |
Box 18 |
Hood - Sprague Dawley - Drink. 1989-1990
|
|
Hood - Sprague Dawley - NaCl Preference Threshold. 1989-1991 |
|
Hooded Female Rats Ca Deficiency Diet. 1958 |
|
HTP on TST (Tail Skin Temperature) - 8H-DTAT, Metergoline (1). 1980-1994 |
|
HTP on TST (Tail Skin Temperature) - 8H-DTAT, Metergoline (2). 1993-1994 |
|
HTP on TST (Tail Skin Temperature) - 8H-DTAT, Metergoline (3). 1993-1994 |
|
Hydrochlorothiazide Experiment 3 - NaCl Intake. Not Dated |
|
Hydrochlorothiazide Experiment 7. 1963-1964 |
|
Hydrochlorothiazide - Iodide Deficiency Experiments. 1961 |
|
Hydrochlorothiazide (HCZ) Taste-Threshold Experiment (Deborah Leigh Giles). 1966 |
|
Hydrodiuril and Aldactone Experiment 5. 1960 |
|
Hydroxytryptamine and DUP 753 Serotonin. 1993 |
|
Hyperhydrating Effects of Angiotensin II. 1991 |
|
Hyperhydration - AII and NaCl Loads. Not Dated |
|
Hyperhydration and Tolerance to Heat. 1991-1992 |
|
Hyperhydration - Hooded Rats Angiotensin I and II. 1991 |
|
Hyperhydration - NaCl Solution. 1991-1992 |
|
Hyperhydration Study. 1992 |
|
Hypertension and Cold Exposure. 1974 |
|
Hypertension - High Fat. 1982 |
|
Hypertension - I131 Uptake and Release Experiment 5. 1969 |
|
Hypertension - I131 Uptake and Release Experiment 6. 1969 |
|
Hypertension in Hypox Rats. Circa 1959 |
|
Hypertension - NaCl, Water Intake. 1979 |
|
Hypertension - Thyroxine I131 Study. 1967 |
|
Hypertensive Rats. 1952-1956 |
|
Hypertensive Rats - Blood Pressure Enovid Experiment). 1969-1970 |
|
Hypertensive Rats - Release Rate Study. 1971-1972 |
|
Hypertensive Rats - Systolic Blood Pressure. 1971 |
|
Hypophysectomized Rats and AII Study. 1992 |
Box 19 |
Hypophysectomized Rats. 1985-1988
|
|
Hypophysectomized Rats. 1985 |
|
Hypothyroidism and Heat Tolerance. 1959 |
|
Hypothyroidism - Isoproterenol Tail Temperature Studies. 1974 |
|
Hypothyroidism on Maintenance of Body Temperature. 1957 |
|
Hypox and ACTH Coding Tests Body Cuts Over 100 gms. 1959 |
|
Hypox - Angiotensin Thyroid Effect - Salt Appetite. 1963-1964 |
|
Hypox - Angiotensin. 1964 |
|
Hypox - Angiotensin Experiment. 1964-1971 |
|
Hypox - Angiotensin (Last Experiment). 1971 |
|
Hypox - Combined DOCA-NaCl Intake Experiments. Not Dated |
|
Hypox - DOCA, NaCl Appetite Experiment 1 (Aldosterone). 1964-1966 |
|
Hypox - DOCA, NaCl Appetite Experiment 3. 1970 |
|
Hypox - Norethynodrel. Circa 1971 |
|
Hypox - Pitressin. 1968-1971 |
|
Hypox Rats. 1985-1988 |
|
Hypox Rats - Cortisone Acetate on Glucose Intake. 1964-1965 |
|
Hypox Rats - Ethynyl Estradiol. 1968-1971 |
|
Hypox Rats - Experiment 2 (M. Dekle). 1964-1966 |
|
Hypox Rats - PTU. 1960-1962 |
|
Hypox Rats - Urine Collections, PTU). 1958-1959 |
|
Hypox - Renin and Pitressin. 1966 |
|
Hypox - Salt Appetite (Testosterone). 1968-1971 |
|
Hypox - Salt Hypertension Study 3. 1959-1960 |
|
Hypox - Summary Tables. Circa 1971 |
|
Hypox - Thyroid Experiment. 1961-1962 |
|
I131 Release from Rats. 1962 |
|
I131 Release Rate Study. 1972 |
|
I131 Thyroid Whole Body Uptake Study. 1972-1974 |
|
I131 Uptake Within the First Eight Hours After Injection. 1973 |
|
Indomethacin Drink Experiment on Isoproterenol Drink. 1977-1980 |
|
Indomethacin Study. 1992 |
Box 20 |
Insulin - Normal Rats. 1966
|
|
Intake Study of Purina Chow, Na Deficient Food and Na Deficient Food with 4% NaCl. Circa 1978 |
|
Intake Study of Purina Chow, Na Deficient Food and Na Deficient Food with 4% NaCl (Group Data). Circa 1978 |
|
Intake Study of Purina Chow, Na Deficient Food and Na Deficient Food with 4% NaCl (Individual Study). Circa 1978 |
|
Intake Study for Thyroxin Threshold. 1971-1973 |
|
Intestinal Smooth Muscles. 1955-1956 |
|
Intraperitoneal and Intragastric Load on Drinking. 1985-1992 |
|
Iodide Electrode - Data (Includes Journal Articles and Notes). 1969-1971 |
|
Iodide Electrode - Varying Iodide Concentrations on Lactoperoxidase Reaction. 1971-1974 |
|
Iodide Electrode - Varying Iodide Concentrations of H2O2 on Lactoperoxidase Reaction. 1976 |
|
Iodination of AII. 1990 |
|
Iodine Deficiency Experiment 9. 1957-1958 |
|
Iodine Deficient Diet - Encap Rats. 1979 |
|
Iodine - Low Iodine TDF Experiments on Rats. 1971 |
|
Isopropyl Sodium Carboxylate Sydnone. 1962 |
|
Isoproterenol - Angiotensin II Interaction. 1978-1982 |
|
Isoproterenol Drink - Effect of Propanolol, Practolol. 1974-1975 |
|
Isoproterenol Hyperhydration. 1991-1992 |
|
Isoproterenol Hyperhydration. 1991 |
|
Isoproterenol Study on Tail Skin Temperature. 1992 |
|
Isuprel Studies - Tail Temperature. 1971 |
|
K Deficiency and Supplemental Diets. 1960 |
|
KCL Experiment. 1962-1963 |
|
KNO3 and DOCA Treated Rats. 1960-1961 |
|
L-5-Hydroxytryptophan and Distilled Water Load. 1980-1993 |
|
L-5-Hydroxytryptophan in the Rat (Mini-Pump Study). 1980 |
|
L-5-OH Tryptophan. 1979-1985 |
|
L-5-OH Tryptophan Atropine SO4. 1980 |
|
L-Thyroxine. 1961-1962 |
|
L-Thyroxine Injection. 1941-1969 |
|
Lactic Acid Experiments (Days 1-4). 1991 |
|
Lactic Acid Experiments (Days 5-8). 1991 |
|
Lactoperoxidase System (Resorcinol and Iodide). 1973-1974 |
|
Lesion and Renal Encapsulated Rats. 1977-1978 |
|
Lesion and Renal Encapsulated Rats. 1977-1978 |
|
Lesion Diuresis. 1966 |
|
Lesioned Rats. 1980 |
|
LiCl Experiment. 1957 |
|
Liquid Diet Cold. 1990 |
Box 21 |
Lithium and Aldomet on Drinking Response to Isoproterenol (Includes Journal Articles). 1969-1976
|
|
Liver Powder. 1963 |
|
Locus Coerulens Lesion Study. 1979 |
|
Low Dose of O,P-DDD on the Development of Hypertension. 1963 |
|
Low Sodium Dietary Study. 1986-1987 |
|
Male Encapsulated Hypertensive Study 3B. 1967 |
|
Maltose - Oral Contraception. 1974 |
|
Maltose Taste Threshold (Estrogen-Treated Rats). 1976 |
|
Medroxy Progesterone Intake Experiment. 1973 |
|
Metabolic Responses to Heat. 1966-1967 |
|
Methazolamide I131. 1963-1966 |
|
Methazolamide - NaHCO3 Intake. 1965-1966 |
|
Methylphenidate. Circa 1963 |
|
MK-421 (Water Intake, Dehydration). 1981-1982 |
|
Mouse Salivary Gland Experiment. 1972-1973 |
|
Mouthwash Data. 1979 |
|
Na and K Balance Diet Study. 1975 |
|
Na Balance (Adrex and Control). 1965-1966 |
|
Na Balance (Control). 1966 |
|
Na Balance (Control). 1966 |
|
Na Balance (Hypothalamic Lesion and Control). 1966 |
|
Na Balance (Normal). Circa 1965 |
|
NaCl and Vasopressin Study. 1992 |
|
NaCl and Water Intake I-Treated Rats (Winona Experiments 1-3). 1958-1959 |
|
NaCl Appetite of PTU-Treated Rats. 1961 |
|
NaCl Intake and Diuresis Studies. 1976 |
|
NaCl Intake Experiment 1. 1964-1965 |
|
NaCl Intake - Hypertensive Rats. 1955 |
|
NaCl Intake - Hypertensive Rats (Aldactone, DOCA). 1964-1966 |
|
NaCl Intake - Hypertensive Rats (Effect on PTU). 1957 |
|
NaCl Intake on Female Blue Spruce Adrex and DOCA. 1975-1976 |
|
NaCl vs. Na2CO3 Intake. 1981 |
|
NaCl Water and Food in Tapazole and Thiouracil Diet Rats. 1959 |
|
NEFA Data and PBI Data Summaries - TDF Extractions. Not Dated |
|
Niacinomide. 1992 |
Box 22 |
Nicotinamide (Ora's Old Rats). 1986-1987
|
|
Nicotine Study. 1981-1982 |
|
Nicotinic Acid - DOCA Hypertension. 1986 |
|
Nicotinic Acid - Normal Rats. 1986 |
|
Nicotinic Acid Study II (Folder 1 of 2). 1986-1987 |
|
Nicotinic Acid Study II (Folder 2 of 2). 1986-1987 |
|
Norethynodrel - Effect on NaCl Intake in Intact and Adrex Rats. 1972 |
|
Norethynodrel - Tube Implants. 1972 |
|
Octopamine (Clyde Williams). 1977-1983 |
|
O,P'-DDD Experiment 3. Circa 1962 |
|
O,P'-DDD Experiment 4. Circa 1960-1962 |
|
O,P'-DDD Experiment 5. Circa 1961 |
|
O,P'-DDD Experiment 6. 1961-1968 |
|
Oral Contraceptive - Salt Appetite Tables. Circa 1976 |
|
Orchidectomy Experiment. 1959-1962 |
|
Osmolarity Experiments. 1967-1979 |
|
Osmolarity PTU-Treated Rats. 1959-1960 |
|
Ovariectomy - Class Experiment. 1959-1962 |
|
Ovex-DOCA-Estrogen and Hypertension. Not Dated |
|
Oxygen Concentration and Bath Temperature for Ovex and Tube Rats. 1977 |
|
Oxygen Concentration in Warm Water. 1958-1959 |
|
Oxygen Concentrations and Colonic Temperature for EE10, EE20 Control Rats. 1977 |
|
Oxygen Concentrations and Heat Loss Studies. Not Dated |
|
Oxygen Consumption. 1994 |
|
Oxygen Consumption (2). 1994 |
|
Oxygen Consumption (3). 1994-1995 |
Box 23 |
Oxygen Consumption and Heat Changes During Cold Exposure. 1974
|
|
Oxygen Consumption During Cooling (PTU vs. Control). 1959 |
|
Oxygen Consumption in 10 Degrees Celsius Water (Adrex Rats). 1959 |
|
Oxygen Consumption PTU-Treated and Normal Rats. 1959-1960 |
|
Oxygen Consumption Study. Not Dated |
|
PBI Results (Wet Ashing Method). 1967-1970 |
|
Phentolamine AII and Saline Study. 1984-1992 |
|
Phenylephrine and Norepinephrine on Tail Skin and Colonic Temperature (in Rats). 1976 |
|
Post-Cold Drink - Central Captopril. 1983 |
|
Post-Cold Drink (Sprague Dawley). 1978-1989 |
|
Post-Cold Drink (Sprague Dawley). 1981-1989 |
|
Post-Cold Drinks (Water Loads). 1980 |
|
Potassium Gluconate - NaCl Appetite (Normal Rats). 1964-1966 |
|
Preference Threshold, Enovid Treated Hooded Rats. Not Dated |
|
Pregnancy Studies. Circa 1953-1954 |
|
Preventing Hypertension with Sulfaminouracil and CoCl2. 1963-1964 |
|
Progesterone Hypertension III. 1975 |
|
Progesterone - Hypertensive Rats. 1975 |
|
Propranolol and Butoxamine. 1981 |
|
Propranolol in Isoproterenol and Phenylephrine on Tail and Colonic Temperature. 1974 |
|
Propranolol on NaCl Appetite. 1983-1984 |
|
Propranolol, Practolol and Butoxamine on Post Cold Drinking. 1976-1977 |
|
Propranolol Study. 1984 |
|
Propranolol Test Rats (Effect of Various Amounts of AII). 1992 |
|
Protein Bound Iodine (PBI) Determination. 1958 |
|
PTU - Activity Experiment 2. 1958 |
|
PTU - Aldosterone (NaCl Appetite) Angiotensin - DOCA. 1965 |
|
PTU and Theophylline. 1967 |
|
PTU and Thyroxine on Testicular Hypertrophy. 1963 |
|
PTU - Angiotensin, Aldosterone, Pitressin Tannate. 1965 |
|
PTU - DOCA Angiotensin. 1967 |
|
PTU - DOCA Taste Threshold. 1968 |
|
PTU - Effect on NaCl Appetite of Adrex Rats. 1959 |
Box 24 |
PTU - HCG (Padgett). 1959-1960
|
|
PTU - Heat Exposure. 1963 |
|
PTU - Hypertension Experiments 1-4. 1956-1957 |
|
PTU - Hypertensive Experiment 5A. 1957 |
|
PTU - Na Balance Study. 1958 |
|
PTU - Na Balance #2 Dehydration Experiment. 1959 |
|
PTU - Na Balance #3. 1959 |
|
PTU - Na Balance #4. 1959 |
|
PTU - Na Balance #5. 1961 |
|
PTU - Na Balance #6. 1961 |
|
PTU - Na Deficiency Study. 1965 |
|
PTU - NaCl Appetite (Estone Corticosterone Renin). 1964-1965 |
|
PTU - Normal Rats Experiment 5. 1957 |
|
PTU, Pitressin and Oxytocin Study. 1966 |
|
PTU Taste Threshold 1-2. 1964-1968 |
|
PTU Thiouracil Treatment Male and Female Experiment 6. 1957 |
|
PTU-Treated Rats (Correspondence Included). 1959 |
|
PTU-Treated Rats NaCl Intake (Effect of Angiotensin, Pitressin, Aldosterone). 1964-1965 |
|
PTU - Urea Taste Threshold. 1965 |
|
Pyridoxal Phosphate and Pyridoxine HCl Study. 1987-1988 |
|
Quinolic and Anthranilic Acids. 1987 |
|
Quinolic and Anthranilic Acids. 1987 |
|
Rabbit Ear Temperature. 1993 |
|
Radioactive I131 Release Rate Study - Body Count. 1972 |
|
Radioactive I131 Release Rate Study (I). 1972 |
|
Radioactive I131 Release Rate Study (II). 1972 |
|
Rat Dehydration (24 Hours Dehydration). 1959 |
|
Rats Treated with Pilocarpine and Bethanechol. 1980-1982 |
|
Reduced B-Adrenergic Responsiveness in Rats. 1974 |
|
Regression Program. 1967 |
|
Relationship Between Blood Pressure and Organ Weight in Rats. 1961-1962 |
|
Renal Encap Rats (CPP - S-720-22, 5 CHTP). 1966 |
|
Renal Encap Rats (Includes Journal Articles). 1974 |
|
Renal Extractions Thyroid Slice Incubation. 1968-1969 |
|
Renal Factor - Effect of Rat Renal Extract on Blood Pressure of Hypertensives. 1969-1970 |
|
Renin and Angiotensin on Thyroid Gland. 1960-1961 |
|
Renin Activity in Hypertensive Rats (Plasma). 1981 |
|
Renin Angiotensin Aldosterone. 1958-1984 |
Box 25 |
Renin - Cold-Treated Rats - Drinking Response. 1976
|
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