Skip to Search




A Guide to the Melvin J. Fregly Papers

Finding aid prepared by John R. Nemmers

University of Florida Smathers Libraries - Special and Area Studies Collections
June 2005

 

Melvin J. Fregly

Descriptive Summary

Creator: Fregly, Melvin J., 1925-1996
Title: Melvin J. Fregly Papers
Dates: 1932-2003
Abstract: Research files, writings, correspondence, and other papers of physiologist and educator, Melvin J. Fregly.
Extent: 74.5 Linear feet. 76 boxes.
Identification: Ms Coll. 117
Language(s): English
Access: Researchers should consult with Special Collections staff before using the collection because there are access restrictions. See the Access note for more information.
Location: IMPORTANT: Please note that this collection is housed in the Auxiliary Library Facility off campus and will require advance notice for timely retrieval. Please contact the Special and Area Studies Collections department prior to your visit.

Biographical/Historical Note

Physiologist, educator. Melvin J. Fregly was born in Patton, Pennsylvania, on May 26, 1925. He was educated in Patton public schools and graduated valedictorian of his 1943 class at Patton High School. Following graduation, he was inducted into the U.S. Army and served for the next three years in the Southeast Pacific Theater during World War II, including New Guinea, the Philippine Islands, and Japan.

Following military service, Fregly enrolled at Bucknell University in Pennsylvania and earned his B.S. and M.S. degrees in Biology in 1949. He received his Ph.D. in Physiology in 1952 from the University of Rochester in New York. He accepted a position as Instructor in Physiology at Harvard Medical School and remained in the position until 1956, at which time he was appointed Assistant Professor of Physiology at the University of Florida College of Medicine in Gainesville, Florida. Dr. Fregly was promoted to Associate Professor in 1960 and to Professor in 1965. He served as Acting Chair of the Department of Physiology for one academic year (1964-1965), and from 1967 until 1971 he served as Assistant Dean for Graduation Education at the College of Medicine. In 1979, the University of Florida honored him with the title of Graduate Research Professor.

His primary area of research was the endocrinological and nutritional aspects of hypertension (high blood pressure), body temperature regulation, behavior, and fluid and electrolyte balance. Several of his studies investigated certain factors, such as catecholamines or chronic ingestion of oral contraceptives, which might induce hypertension. Other experiments focused on those agents, such as tryptophan, which might protect against the development of hypertension. Another major research area examined behavior, specifically the preference for salt, the mechanisms controlling salt appetite, and excessive ingestion of salt that might lead to hypertension. His studies in this area focused on the adrenal gland and its hormone, aldosterone, as well as the hormone, angiotensin II. Related research activities included thirst and drinking, altitude, and cold-induced hypertension. Dr. Fregly authored or co-authored more than 500 publications, including four books, and contributed chapters to over 50 books.

He was a member of several professional societies including the American Physiological Society, the Canadian Physiological Society, the Endocrine Society, the American Thyroid Association, the American Heart Association, and the Society for Experimental Biology and Medicine. He served as consultant to the Strasenburgh Pharmaceutical Company (1965-1967) and to the National Institutes of Health as a member of the Respiration and Applied Physiology Study Section (1987-1991). In the early 1990s, he served on the American Institute of Biological Sciences' Advisory Panel for NASA, the NASA Regulatory Physiology Discipline Working Group, and the Space Station Science and Advisory Subcommittee to NASA.

Dr. Fregly died in 1996.


Scope and Content

Correspondence, research material, writings, speeches, notes, photographs, printed publications, and other records make up the Melvin J. Fregly Papers (1932-2003). The collection primarily documents his professional activities from 1956 until his death in 1996, and most notably contains all of his research files and writings. The largest group of files within the collection is Series 2: Research Files (1941-1996), which documents the extensive research conducted over a span of forty years by Dr. Fregly in areas such as hypertension, salt preference and appetite, body temperature, and fluid and electrolyte balance. His research productivity is clearly demonstrated by the large size of the Publications and Writings Series (Series 8; 1949-1997), which includes journal articles, monographs, chapters in books, reviews, and an assortment of other writings. Several other groups of files also relate directly to his research, and include material such as notes and notebooks, photographs of experiments and experiment results, writings by other researchers, and speeches.

In addition, the collection contains Dr. Fregly's correspondence, personal papers and memorabilia, and papers pertaining to his teaching and professional activities as a member of the University of Florida faculty. Of particular interest is the Patent and Financial Files Series (1987-1999), which is comprised of legal and financial material, as well as associated correspondence and news clippings, concerning patents held by Fregly. Several files in this series pertain to the thirst quencher beverage TQII invented by Fregly, J.R. Cade, and M. Privette. Their patent to this invention was the subject of law suits by Quaker Oats, which claimed that the beverage was too similar to Gatorade (also created by Cade and owned by Quaker).

The collection is organized into 15 series, or groups of files:

  • 1. Correspondence, 1946-1996
  • 2. Research Files, 1941-1996
  • 3. Cold Research, 1951-1995
  • 4. Research Notebooks, 1952-1956
  • 5. Research Recording Charts (Heart Rate, Temperature, etc.), 1972-1986
  • 6. Research Grants, 1952-1998
  • 7. Notes, 1947-1976
  • 8. Publications and Writings, 1949-1997
  • 9. Writings by Others, 1932-1991
  • 10. Teaching Materials and University of Florida Files, 1949-1994
  • 11. Speeches and Seminars, 1933-1994
  • 12. Photographs, 1944-1994
  • 13. Patent and Financial Files, 1987-1999
  • 14. Personal and Miscellaneous, 1943-2003
  • 15. Computer Media, Not Dated

It should be noted that Fregly and his assistants often used abbreviations when creating folder titles. Therefore, files related to salt research might be written as "sodium chloride," or as "NaCl," or simply as "salt." Likewise, some elements are often referred to by their symbol on the periodic table (e.g., "K" instead of "potassium") and many drugs and medical terms are abbreviated. In addition, some terms have multiple abbreviations used inconsistently throughout the files. The term "adrenalectomized," for example, is abbreviated as adrenal, adrex, adex, or adx.


Access or Use Restrictions

Access

The collection is open for research. Please note, however, that this collection is housed in the Auxiliary Library Facility off campus and will require advance notice for timely retrieval. Please contact the Special and Area Studies Collections department prior to your visit.


Administrative Information

Alternate Form of Finding Aid

Due to its large size an alternate version of this descriptive finding aid, broken into several pages, is available at http://www.library.ufl.edu/spec/archome/fregly.htm.

Preferred Citation

[Identification of item], Melvin J. Fregly Papers, Special and Area Studies Collections, George A. Smathers Libraries, University of Florida, Gainesville, Florida.

Acquisition Information

The Fregly Papers were donated by Marilyn S. Fregly of Gainesville, Florida, in 1998.


Contents List

Correspondence 1946-1996

Consists primarily of correspondence related to the field of physiology, Fregly's research and publications, his activities related to professional societies, and general correspondence with colleagues, friends, and former students. Correspondents include E.F. Adolph, Robert Cade, Christopher Barney, I.W. Waters, and Kenneth Cook, among others. Professional societies include the American Physiological Society, the American Heart Association, the Canadian Physiological Society. Correspondence related to his work as a consultant with Strasenburgh Laboratories and the NASA Space Station Science and Applications Advisory Subcommittee is also included. In addition to the files in this series, correspondence related to his academic activities in the Department of Physiology at the University of Florida can be found in the Teaching Materials and University of Florida series.


Box
1 Academic Freedom and Responsibility. 1962-1963
1 Adolph, E.F. 1952-1987
1 Adolph, E.F. (Biographical) Folder 1 of 2. 1971-1987
1 Adolph, E.F. (Biographical) Folder 2 of 2. 1971-1987
1 American Bakers Association. 1982
1 American Cyanamid Company. 1966-1968
1 American Cyanamid Company (Experiment - Therapeutics Research). 1967-1969
1 American Heart Association. 1980
1 American Heart Association (includes application for grant: Regulation of Sodium Intake by Hypertensive Rats). 1957-1959
1 American Thyroid Association - Phoenix Convention. 1985-1986
1 American Physiological Society. 1951-1983
1 American Physiological Society (Milestone in Thermal Physiology - Symposium). 1995-1996
1 Barney, Christopher C. 1977-1982
1 Biological Handbooks (Federation of American Societies for Experimental Biology). 1957-1960
1 Biological Test Diets. 1953-1959
1 Blood Pressure Measurement. 1959-1961
1 Book Review - Sodium, Its Biological Significance. 1982
1 Boyd, R. Lee. 1980-1985
1 Britton, Amy - University of Toronto (includes copy of research report on serum T4). Circa 1964
1 Bryan, Betsy. 1980-1983
1 Burns, Alastair. 1971-1978
1 Cade, Robert. 1995
1 Canadian Physiological Society. 1965-1969
1 Caputo, Florence (Recommendations). 1987-1993
1 Carlberg, Karen. 1987
1 Contraceptive Evaluation Branch - Center for Population Research. 1977-1978
1 Cook, Kenneth. 1957-1963
1 Correspondence Related to the International Conference on Implementing Dietary Guidelines. 1980-1981
1 Correspondence While at Harvard Medical School. 1952-1957
1 Course in Radioisotope Techniques (Oak Ridge Institute of Nuclear Studies, Tennessee). 1959-1960
1 Cross-Adaptations and Their Significance (Article to be Published). 1971
1 Data on Organ Weights - Jose L. Torres. 1985
1 Development of Human Flavor Perception (Seminar at UF, Dr. Gary K. Beauchamp). 1992-1993
1 Drug Companies (Requests for Drug Samples). 1956-1963
1 Federation Meeting. 1984-1985
1 Field, F. Peter (Former Graduate Student). 1967-1988
1 Fitzsimmons, James (Symposium Honoring His Retirement). 1995
1 Flame Photometer. 1956-1960
1 Fregly, B.J. (Nephew). 1985-1986
1 Geigy (Canada) Limited - Pharmaceuticals Division. 1967-1970
1 General Correspondence. 1949-1959
2 General Correspondence. 1949-1959
2 General Correspondence. 1959-1961
2 General Correspondence. 1959-1974
2 General Correspondence. 1963-1968
2 General Correspondence. 1965-1973
2 General Correspondence. 1967-1975
2 General Correspondence. 1985-1995
2 Gordon, David. 1975-1988
2 Gwosdow, Andrea. 1982-1985
2 Hathaway, Susan. 1984-1988
2 Henley, William. 1984-1986
2 Heroux, O. (National Research Council of Canada). 1967-1969
2 Horwitz, Barbara. 1987
2 Iampietro, P.F. 1959-1962
2 Interaction of Adrenal and Thyroid Glands (American Physiological Society). 1960
2 International Congress of Physiological Sciences (India). 1974
2 Invitation Letters. 1986-1987
2 Johansen, Audhild (Norway). 1989
2 Kare, Morley. 1983
2 Kelleher, Dennis L. 1973-1988
2 Keller-Wood, Maureen. Not Dated
2 Kellogg, Ralph H. (Regarding Dr. Adolph). 1992
2 Kiely, James. 1985
2 Kikta, Dianne C. (Includes journal articles by others). 1972-1988
2 Lambert, Charles R. 1975-1982
2 Lee, Douglas H.K. 1966-1967
2 Leonpacher, Robert J. 1979
2 Life Insurance Medical Research Fund (Includes research proposal, grant application: Regulation of Water and Sodium Intake by Hypertensive Rats). 1956-1959
2 Lighty, George W., Jr. 1968-1971
2 Lockley, Ora. 1985-1990
2 Lutherer, Lorenz O. (includes curriculum vita). 1968-1988
2 MacArthur, Sally. 1977-1979
2 Magyar, Regis (Includes Program of Study, Dissertation). 1979
2 McCaa, Robert E. 1987
2 McCaron, David. 1990-1991
2 McCarthy, Jeane Stuhlsatz (Includes reference reports and recommendations by Fregly). 1964-1976
2 Medical College of Wisconsin. 1978-1979
2 Menendez, Eduardo Braun. 1956-1958
2 Merck Sharp and Dohme - Research Laboratories. 1957
2 Miller, Emily. 1980
2 Morris, Paul. 1984-1985
2 Mudd, Laura M. (Includes NRSA Application). 1985-1986
2 Myers, Linda M. 1986-1987
2 NASA Space Station Science and Applications Advisory Subcommittee. 1992-1994
2 Nelson, Eldon. 1978-1990
2 Newsome, Deborah G. 1975-1982
2 Oosterwagel, Mariette (Netherlands). 1986
2 Otis, Arthur B. (Professor in the Netherlands, Katholieke University). 1964-1965
2 Oxygen Analyzer. 1958
2 Papanek, Paula. 1985-1989
3 Paque, Claude. 1986
3 Permission to Quote from Published Articles. 1970
3 Pharmacology and Thermoregulation. 1996
3 Pharmacology, Biochemistry and Behavior. 1980
3 Post-Cold Drinking Response - Write Up. 1965-1966
3 Puri, Sudha. 1988
3 Queen's College (Canada). 1985
3 Radford, E.P. 1955-1962
3 Radioimmunoassay for Aldosterone (Karen Carlberg). 1983
3 Recommendation for Fregly as Chairperson for the EEP Section (American Physiological Society). 1993
3 Reininger, Edward J. 1983-1987
3 Regarding Book - Human Endocrinology. 1979-1991
3 Regarding Journal Articles by Andrea Gwosdow (former student). 1985
3 Regarding Research on the Effect of Adrenal Cortical Hormones. 1960-1964
3 Request for Additional Supply of Chemical Compounds. 1983-1985
3 Requests for Drug Samples. 1986-1988
3 Requests for Reprints and Thank-You Letter. 1954-1955
3 Request for Travel Grant to Attend International Physiological Congress, Buenos Aires, Argentina (Includes Notes). 1958-1959
3 Resch, Garth E. (Includes curriculum vita). 1971-1976
3 Ress, Rudyard (Includes research material). 1978-1980
3 Reyes, Cesar. 1984-1985
3 Role of Salt in Cardiovascular Hypertension Symposium. 1961-1962
3 Role of Salt in Cardiovascular Hypertension Symposium. 1960-1962
3 Rudolph, Lucky. 1988
3 Sabbatical Year. 1971
3 Salt Symposium - Alan Epstein. 1990-1991
3 San Martin, Raul. 1957-1962
3 Scammell, Johnathan G. 1980-1987
3 Schwartz, Michael. 1981-1988
3 Shechtman, Orit (Includes curriculum vita, progress reports, etc.). 1987-1993
3 La Semaine des Hopitaux: Pathologie et Biologie (Paris). 1957-1960
3 Silastic Kidney Capsules. 1964-1972
3 Sisson, George. 1953-1956
3 Society for Experimental Biology and Medicine. 1995
3 Southern Salt Water and Kidney Club. 1988-1995
3 Spiers, Donald. 1978-1983
3 Strasenburgh Laboratories. 1965-1967
3 Strasenburgh Laboratories. 1966
3 Strasenburgh Laboratories (Includes notes and invention disclosure records). 1961-1967
3 Straw, James (Includes curriculum vita, journal articles, etc.). 1963-1982
3 Stroll Associates. 1984
3 Sullivan, Andrew J. 1983
3 Symposium - Role of Sodium in Hypertension (University of British Columbia). 1980-1981
3 Taylor, Robert E., Jr. 1963-1976
3 TEKLAD - Regarding Calcium Diet. 1988
3 Thrasher, Terry N. (Includes curriculum vita). 1973-1989
3 Threatte, Rose M. (Includes research paper). 1978-1985
3 Tobian, Louis (Department of Medicine, University of Minnesota). 1957-1959
3 Travel - Correspondence with Travel Agencies, Organizations, Universities, etc. 1955-1956
3 Van Bergen, Patricia (Netherlands). 1988-1989
3 Van der Voort, Judith (Netherlands). 1985-1987
3 Van Deusen, Wayne. 1983-1984
3 Veterans Administration. 1946-1950
3 Volume Recorder. 1957-1958
3 Waters, I. Wade. 1962-1967
3 Wikkeling, O.R. Marald (Netherlands). 1986-1988
3 Wilson, Karen M. 1984-1989


Research Files 1941-1996

Materials related to Fregly's research, including experiment methodology, data, notes, conclusions, and preliminary writings describing results. The files represent all of his areas of research, including hypertension (high blood pressure), body temperature regulation, behavior, and fluid and electrolyte balance. Frequent topics include the thyroid, tryptophan, catecholamines, propylthiouracil (PTU), oral contraceptives, salt preference and appetite, the adrenal gland, aldosterone, angiotensin II (AII), hydrochlorothiazide (HCZ), thirst and drinking, thyroid depressing factor (TDF), altitude and cold, hypothyroidism, isoproterenol, DOCA-salt, running activity, aminotriazole (ATZ), enovid, hypoxia, captopril, and nicotinic acid.

It should be noted that this Research Files series does not include all materials related to Fregly's research. For example, the collection also includes a series pertaining to his Cold Research, the Research Notebooks series, the Research Recording Charts series, and the Research Grants series. Further, the writings used to report the results of research studies are found in Publications and Writings series.


Box
4 2-Methoxyphenyl Piperazine Data. 1987
4 5-HTP Renal Hypertension Pyridoxine HCL and Tryptophan. 1988-1989
4 5-HTP - Urinary Catecholamines. 1982
4 Acetylchlorothiazide Experiment 1. 1963
4 Acetylchlorothiazide Experiment 2. 1963
4 Acetylchlorothiazide Experiment 3. 1963-1964
4 Activity Experiment - Oral Contraceptives. 1967-1969
4 Activity of TDF Fractions, Effect of Varying Lactoperoxidase Concentration. 1975
4 Activity-PTU Experiment 1. 1958
4 Activity-PTU Experiment 3. 1958
4 Activity Study - Serotonin. 1980
4 Adrenal Cholesterol. 1956-1957
4 Adrenalectomized Rats. 1973-1974
4 Adrenalectomized Study (Rats). 1987
4 Adrenalectomized Study (Rats). 1987
4 Adrenalectomized Study (Rats). 1987
4 Adrenalectomy. 1959
4 Adrenalectomy. 1987-1988
4 Adrenalectomy - Aldosterone Diuresis. 1969
4 Adrex, Angiotensin, Aldosterone. 1964
4 Adrex - Angiotensin (LITT) #1. Not Dated
4 Adrex Diuresis Experiments (1). 1965
4 Adrex Diuresis Experiments (2). 1966
4 Adrex Diuresis Experiments (3). 1968-1969
4 Adrex - DOCA Experiment #2. 1966
4 Adrex Experiments. 1979
4 Adrex - NaCl Appetite (Effects of Corticosterone, DOCA and Testosterone). 1964
4 Adrex - Rats on Salt Solution. 1958
4 Adrex - Salt Appetite. 1957
4 Adrex - Salt Hypertension Experiment 2. 1958
4 Adx and Adx Encapsulated. 1958
4 Adx Encap Experiment 3. 1957
4 Adx Encap Experiment 3. 1957-1958
4 AII (Angiotensin II) and DUP 753 Study. 1991-1992
4 AII (Angiotensin II) and Glucose Loads Study. 1992
4 AII (Angiotensin II) and Isoproterenol. 1993
4 AII (Angiotensin II) and Isoproterenol on EB Rats. 1984-1985
4 AII (Angiotensin II) and NaCl Study on Rats. 1992
5 AII (Angiotensin II) and NaCl Study. 1992
5 AII (Angiotensin II) and UK Drink Study. 1987-1988
5 AII (Angiotensin II) and V-Blocker. 1990
5 AII (Angiotensin II), ANF and TDF Drink. 1985
5 AII (Angiotensin II) on DOCA Study. 1992
5 AII (Angiotensin II) with Varied Concentration of NaCl to Drink. 1992
5 Alcohol Diuresis. 1965-1966
5 Aldactone on Enovid Salt Appetite. 1972-1973
5 Aldosterone, DOCA, Angiotensin Effect on NaCl Appetite of Adrex Rats. 1963
5 Aldosterone Experiment 2 and CoCl2 Experiment. 1963
5 Aldosterone - Experiment on Aldosterone Treated Rats. 1957-1959
5 Aldosterone Hypertension Experiment. 1967
5 Aldosterone Secretion and NaCl Intake. 1963-1967
5 Aldosterone Secretion Rate and NaCl Intake. 1963-1964
5 Altitude Cold Experiments #1-3. 1968-1969
5 Altitude Cold Experiments #4-5. 1969-1970
5 Altitude Cold Experiments #6. 1972
5 Altitude Cold Experiments #8. 1973
5 Altitude Cold Experiments #9. 1973-1977
5 Altitude - Cold Experiments Series I. 1951
5 Altitude - Cold Experiments Series II. 1951
5 Altitude - Cold Experiments Series III-IV. 1951-1952
5 Altitude - Cold Experiments Series V. 1952
5 Altitude Experiment. 1964-1966
5 Altitude Experiment #1. 1965-1968
6 Altitude Experiment #2 (12% Oxygen). 1965-1968
6 Altitude Experiment (15% Oxygen). 1964-1966
6 Altitude Experiment (16% Oxygen). 1967-1970
6 Altitude Experiment (17% Oxygen). 1966
6 Altitude Experiment (Completed Analyses). 1964-1966
6 Altitude Experiment - Data. 1964
6 Altitude Experiment - Hypertensive Rats. Not Dated
6 Altitude Experiment - Hypoxia on Blood Pressure and Thyroid Function. 1961-1965
6 Altitude Experiments. 1955-1956
6 Altitude Experiments #1-3. 1960-1961
6 Altitude Experiments #4. 1961-1966
6 Altitude Experiments #I. 1954-1955
6 Altitude Experiments (Urine, Feces, and Osmolarity). 1964
6 Amino Acids and TDF Analysis. 1984-1986
6 Aminophylline Dopamine Blockers. Not Dated
6 Aminotriazole and Hypertension. 1966-1968
6 Angiotensin Autoradiography. Circa 1984-1987
6 Angiotensin II and Creatinine Study. 1977-1984
6 Angiotensin II Drink - Bromocriptine and Dopamine. 1984-1988
6 Angiotensin II Drink - Bromocriptine and Dopamine. 1980-1984
6 Angiotensin Induced Drinking (Spiperone, Atropine). 1984-1988
6 Angiotensin - LITT #2. 1965
6 Angiotensin - Pitressin Adrex Rats. 1963
6 Anthranilic Acid - DOCA Experiment. 1991-1992
6 Antihypertensive Agent - Aldomet. 1962-1963
7 Arginine Study on Rat Colonic and Tail Skin Temperature. 1992-1993
7 Atenolol on Isoproterenol Drink. 1980
7 Atropine and Bethanechol. 1980-1982
7 ATZ (Aminotriazole). 1966-1967
7 ATZ Effect - Acute Diet vs. I.T. 1972
7 ATZ Experiment 1. 1967
7 ATZ Experiment 2. 1967
7 ATZ Hypertension. 1967
7 ATZ - Second Study. 1974
7 ATZ - Single Injection (I131). 1967
7 ATZ Study #3. 1971-1975
7 B-Adrenoceptor Subtype Mediating Tail Skin Temperature of Rats. 1977-1982
7 B-Estradiol 3-Benzoate. 1988
7 Balance Study (Adrex and Normal Rats Given Enovid). 1973-1974
7 Balance Study (Cook). 1957
7 Balance Study (Normal Rats Given Mestranol and Norethynodrel). 1973-1974
7 Balance Study on Normal Male Rats (Norethynodrel and Mestranol). 1974
7 Benserazide-Isoproterenol Study. 1978-1980
7 Benzyl Sulfamic Acid Experiment. 1963
7 Bethanechol - BP Study. 1981
7 Blood Pressure - EB Treated Rats. Not Dated
7 Blood Pressure - EB Treated Rats. Not Dated
7 Blood Pressure - EB Treated Rats. Not Dated
7 Blood Pressure - EB Treated Rats. Not Dated
7 Blood Pressure - Norethynodrel and Ethynyl Estradiol. 1971-1972
7 Blood Pressure of Aldosterone-Treated Rats. Not Dated
7 Blood Pressure Response of Rats Treated with 733-64A. 1966
7 Blood Pressure Studies (Systolic). 1959
7 Blood Pressure Study (6-HMP, 5-CHMP). 1965-1967
7 Blood Volume Dialysis (Includes Journal Articles). 1947-1966
8 Bradykinin, DUP and Captopril. 1992-1993
8 Bromocriptine on Individual Drinking. 1983-1984
8 Calcium-Encap Study 1. 1984
8 Calcium-Encap Study 2. 1984
8 Calcium-Encap Study 3. 1986-1988
8 Calcium-Serum Study. 1968
8 Calcium Study on Rats. 1991
8 Calcium Study - Renal Encapsulated. 1985
8 Calcium Study - Renal Encapsulated. 1985
8 Calcium Study - Renal Encapsulated. 1985
8 Calcium-Tryptophan Diet Study. 1989-1994
8 Calcium-Tryptophan Diet Study. 1994
8 Calcium-Tryptophan DOCA Hypertension. 1989-1994
8 Calcium-Tryptophan DOCA Hypertension. 1989-1994
8 Captopril on NaCl Appetite. 1978-1979
8 Captopril - Renal Hypertension. 1979
8 Captopril - Tryptophan Experiments. 1989
8 Carbethoxy-2-Thiouracil. 1966
8 Carboxytryptamine Test. 1993
8 Cardiovascular and Thyroid Hypertension. Not Dated
8 Catecholamine. 1989
8 Catecholamine Output (Dr. Muther). 1988
8 Catecholamines on Aortic Smooth Muscles. 1975
8 Central Administration of Octopamines and Drinking (Folder 1 of 2). 1983-1984
8 Central Administration of Octopamines and Drinking (Folder 2 of 2). 1983-1984
8 Central vs. Peripheral AII (Angiotensin II). 1983-1984
8 Characterization of Blood Pressure vs. Time Mathematically. Not Dated
9 Chronic Estrogen Treatment on Water Exchange (Fahey). 1983-1984
9 Chronic Estrogen Treatment on Water Exchange (Fahey). 1983-1984
9 Clonidine. 1976-1978
9 Clonidine - Tail Skin Temperature and Heart Rate in Response to Isoproterenol. 1976-1982
9 Cold Adaptation. 1979
9 Cold Experiment - Low Bulk Diet (Debby Giles). 1967
9 Cold Experiment 2. 1988
9 Cold Experiment 4 (BP Traces). 1988
9 Cold Experiments - Food, Water Intake and Urine Output. 1965-1966
9 Cold Experiments - Food, Water Intake and Urine Output. 1965-1968
9 Cold Experiments (Temperature Measurement). 1960
9 Cold Exposure for 20 Days (Harvard). 1952
9 Cold Hypertension Experiments. 1952
9 Cold Rats - Organ Weight and Blood Pressure. 1977
9 Combined AII Drink Catecholamines. 1987-1988
9 Combined AII Drink Catecholamines. 1988
9 Combined AII Drink Catecholamines. 1988-1989
9 Comparison Study of KNO3 and KCl with Respect to Blood Pressure. 1960-1961
9 Compensatory Renal Hypertrophy and Thyroid Activity. 1968-1969
9 Compound S-615-76. 1965
9 Computer Fortran Programs. 1969
9 Contraceptive B - Responses (Thyroid Hormone). 1976-1978
10 Contractile Substance in Plasma and Urine of Rats. Not Dated
10 Control Tube Rats (Tail Skin, Rectal and Air Temperature). 1977
10 Cooling Rates Experiments. 1958-1959
10 Cooling Rates of Rats. 1954-1955
10 Cooling Rates of Rats in Air. 1949-1950
10 Cooling Rate T4 Tube. 1973
10 Cooling Tests on Normal and Adx Rats. 1958
10 Corticosterone Acetate Rats. 1979
10 Corticosterone Acetate Study. 1978-1979
10 Corticosterone on Glucose Intake of Hypox Rats. 1966
10 DA2 - Agonist and Drinking. 1984-1985
10 DDD and Hooded Rats. 1963-1992
10 DDD and PAH Excretion. 1967
10 DDD - Ethionine Experiment. 1966
10 DDD Experiments - Combined Data (Experiments 3-6). 1962
10 DDD on Excretion of Radioactive T4 in Bile. Not Dated
10 Dehydration Induced Drinking. 1980-1982
10 Dehydration - Water, Food Deprivation. 1990
10 Dehydration - Water, Food Deprivation. 1990
10 Deoxycorticosterone Acetate Study. 1983-1984
10 Dexamethasone - Hypox Glucose Experiment. 1966
10 Diamox - Effect on NHCO3 Intake. 1968
10 Direct Blood Pressure Experiments. 1962-1965
10 Direct Blood Pressure Study (Data CA vs. Control). 1983
10 Direct Blood Pressure Study (Data CA vs. Control). 1979-1983
10 Diuresis During Alcohol Ingestion. 1963-1966
10 Diuresis Experiment 1-3. 1966
10 Diuresis Experiments 722-58. 1966
11 Diuresis Experiments 722-70, 730-334. 1966
11 Diuresis Experiments (Dr. Cooper of Toronto). 1969
11 Diuresis Experiments Summary S-720-22. 1965-1966
11 Diuresis Experiments (Water, Urea, KCl, NaCl and Pitressin Diuresis). 1965
11 Diuresis on Female Blue Spruce Rats Treated with Norethynodrel and Ethynyl Estradiol. 1975
11 Diuretics and Renal Iodide Excretion by Humans (HCZ and AZ). 1966-1973
11 Diuril and DOCA Hypertension Experiment 6. 1961-1962
11 Diuril and Hydrodiuril Experiment 3. 1960-1961
11 Diuril Experiment 1. 1959-1960
11 Diuril Experiment 2. 1960
11 DOCA - Adrex Salt Appetite Experiment (Student Experiment). 1965
11 DOCA - Adrex Salt Taste Threshold. Circa 1969
11 DOCA and NaCl Intake (Swartz) Folder 1 of 2. 1964
11 DOCA and NaCl Intake (Swartz) Folder 2 of 2. 1964
11 DOCA and Pyridoxal HCL Study. 1988
11 DOCA and Saline on ANF. 1985-1986
11 DOCA and Tryptophan. 1982-1986
11 DOCA - Estrogen Study. 1987
11 DOCA Males - L-Kynurenine Infusion. 1989-1991
11 DOCA on Preference Threshold for NaCl. 1967
11 DOCA on Salt Appetite of Captopril-Treated Rats. 1984-1985
11 DOCA-Pyridoxal Phosphate Study. 1987
11 DOCA Rats Study. 1987-1992
11 DOCA Salt L-5HTP Study (Ora Lockley) Folder 1 of 2. 1985-1986
11 DOCA Salt L-5HTP Study (Ora Lockley) Folder 2 of 2. 1985-1986
11 DOCA Salt Tryptophan and Pyridoxal HCL. 1988
11 DOCA Salt Tryptophan Experiment (41). 1991
12 DOCA Salt Tryptophan Study (Ora Lockley) Folder 1 of 2. 1986
12 DOCA Salt Tryptophan Study (Ora Lockley) Folder 2 of 2. 1986
12 DOCA Study. 1987-1991
12 DOCA Tryptophan Folder 1 of 2. 1985
12 DOCA Tryptophan Folder 2 of 2. 1985
12 DOCA Tryptophan Folder 1 of 2. 1985
12 DOCA Tryptophan Folder 2 of 2. 1985
12 DOCA Tryptophan Study - Angiotensin II. 1985
12 DOCA Tryptophan Study (Nephrectomy) Folder 1 of 2. 1985
12 DOCA Tryptophan Study (Nephrectomy) Folder 2 of 2. 1985
12 DOCA Tube Experiment. 1984
12 DOCA Tyrosine Experiments. 1985-1986
12 Dogs - Diuresis (Ethacrynic Acid, Aminophylline, etc.). 1967-1970
12 Dogs - Drinking (Diuretics). 1966-1968
12 Dopamine - Blood Pressure. Not Dated
12 Dopamine - Isoproterenol (AII Drinks). 1984-1988
12 DUP 753. 1990-1991
12 DUP and Saralasin Study File 1. 1992
12 DUP and Saralasin Study File 2. 1992
12 DUP and Saralasin Study File 3. 1992
13 EB - Animal Data and Tube Data. 1976-1978
13 EB DOCA Study on Female Rats. 1989
13 EB, Lipolysis and Camp Experiments. 1977
13 Effect of 5,6-Dimethyl-2-Thiouracil on Thyroid Gland. 1966-1967
13 Effect of 5-Methyl Thiouracil on Thyroid Gland of Rats. 1967
13 Effect of Acute Administration of Isotonic Saline on Urine Output in Rats on NaCl Free Diet. 1978
13 Effect of Administration of Haloperidol in Female Rats. 1978-1979
13 Effect of Administration of Haloperidol on Output and Urinary Electrolyte Excretion in Rats. 1978
13 Effect of Adrenalectomy and Treatment with Cortisone Acetate (Student Experiments). 1963
13 Effect of Adrenalectomy and Treatment with Cortisone Acetate (Student Experiments). 1962-1964
13 Effect of AII on Colonic and Tail Skin Temperature. 1993
13 Effect of AII and DUP 753 on Colonic and Tail Skin Temperature. 1992-1993
13 Effect of AII and Isoproterenol on Tail Skin and Colonic Temperature. 1993
13 Effect of AII and Isoproterenol on Tail Skin and Colonic Temperature. 1993
13 Effect of Aldosterone on Salt Intake of Adrex Rats. 1964
13 Effect of Aminotriazole on Thyroxine I131 Metabolism. 1967
13 Effect of Amphenone B on Blood Pressure and Thyroid Function on Rats. 1959-1960
13 Effect of Anti-Thyroid Drugs on Development of Hypertension in Adrenalectomized Rats. 1958
13 Effect of Apomorphine on Rat Water Intake and Urine Output. Not Dated
13 Effect of Atropine on Water Intake Induced by Isoproterenol. 1978-1979
13 Effect of Butyl-4-Ethyl Sydnone on Rat. 1962
13 Effect of Carbichol and CCK on Water Intake and Urine Output. 1993
13 Effect of Chloride-Deficient Diet on Spontaneous Intake of NaCl. 1970
13 Effect of Chronic Administration of Norethynodrel and Ethynyl Estradiol. 1973
13 Effect of Chronic Administration of Norethynodrel and Ethynyl Estradiol. 1973
13 Effect of Chronic Administration of Norethynodrel and Ethynyl Estradiol on Heart Rate and Blood Pressure. 1974
13 Effect of Chronic Exposure to Cold Hypoxia and Both Combined on Water and Electrolyte Exchange (Includes Journal Articles). 1975-1977
13 Effect of Chronic Treatment with Tryptophan. 1986
13 Effect of Chronic Treatment with Tryptophan. 1978-1987
14 Effect of Clonidine on Responses to Graded Doses of Pitressin. 1977-1979
14 Effect of Clonidine and Naloxone on Angiotensin II Induced Drinking. 1983
14 Effect of CNS Lesions on Response to ATZ. 1956-1968
14 Effect of Cold on Hypertensive Rats. 1952
14 Effect of Cold on I131 Uptake and Release. 1973
14 Effect of Cold on Oxygen Response to Isoproterenol. 1975
14 Effect of DDC on Rat Water Intake and Urine Output. 1978-1979
14 Effect of DDD on Insulin Sensitivity and Adrenal Histology of the Monkey. 1955
14 Effect of DDD on Sleeping Time. 1968-1969
14 Effect of Dietary Calcium Supplementation on Blood Pressure. 1984
14 Effect of Dietary Calcium Supplementation on Blood Pressure. 1984
14 Effect of Dietary Taurine on Development of DOCA-Salt Induced Hypertension. Circa 1986
14 Effect of Diuretics on the Rate of Deiodination of I-Thyroxine by Kidney Slices in Vitro. Not Dated
14 Effect of DOCA on NaCl Intake of Normal and Lesioned Rats. 1966
14 Effect of Enovid on NaCl Intake and Excretion (Adrenalectomized Rats). 1972-1973
14 Effect of Estradiol in Rats. 1983-1984
14 Effect of Estrogens on NaCl Intake and Organ Weight of Rats. 1971
14 Effect of Fluid Intake on PTU-Treated Rats. 1958
14 Effect of Graded Doses of an Oral Contraceptive on Spontaneous Activity. 1971
14 Effect of HCZ (Hydrochlorothiazide) on NaHCO3 Intake. Circa 1966
14 Effect of HCZ (Hydrochlorothiazide) on Spontaneous Intake of Sodium Gluconate. 1968
14 Effect of Heat Exposure on Fluid Exchange. Not Dated
14 Effect of Hydrochlorothiazide on Salt Intake of Rats. 1966
14 Effect of Indomethacin on Warm-Adapted Rats. 1976-1985
14 Effect of Intraperitoneal Load of NaCl Solution. 1976
14 Effect of Isoproterenol on Oxygen Consumption and Temperature of Rats. 1977-1981
14 Effect of Isoproterenol on Oxygen Consumption and Temperature of Rats. 1977
14 Effect of Isoproterenol, Saline and Bradykinin in SQ14225 and Captopril-Treated Rats. 1978
14 Effect of Isoproterenol, Saline and Bradykinin in SQ14225 and Captopril-Treated Rats. 1978-1979
14 Effect of Maltose on NaCl Intake. 1984
14 Effect of Maltose on Preference Threshold of Rats. 1968
14 Effect of NaHCO3 on Spontaneous Intake of NaCl Solutions in Rats. 1969
14 Effect of Neuropeptide on Colonic and Tail Skin Temperature. 1993
14 Effect of Ng/K Ratio of Salt Solution. 1966-1994
15 Effect of Norethynodrel on Hypertensive Rats. 1972-1973
15 Effect of O,P-DDD on Fecal and Urinary Excretion of Radioactivity. 1955-1966
15 Effect of Parachlorophenylalanine on the Rat. 1978-1979
15 Effect of Phentolamine and Isoproterenol on Induced Drinking (Estrogen Treated Rats). 1981-1982
15 Effect of Phenylephrine on Urinary Flow, Na and K Output. 1975-1976
15 Effect of Prazosin on Angiotensin II Induced Drinking in Female Rats. 1983-1984
15 Effect of PTU on Organ Weight/Body Weight of PTU Treated, Normal and Hypertensive Rats. 1956-1964
15 Effect of PTU on Thyroid Weight and Function of Rats. 1967
15 Effect of Renal Extract on Urine Flow. 1971
15 Effect of S615-76 on Dogs and Cats. 1964
15 Effect of Salt on Growth of PTU Treated Rats. 1959-1961
15 Effect of Sulfaminouracil on the Ratio of Organ Weight to Body Weight. 1963
15 Effect of Tail Skin Temperature on Response to Isoproterenol. Not Dated
15 Effect of TDF on Frog Skin. 1983-1985
15 Effect of TDF and Isoproterenol on Water Intake and Urine Output. 1980-1981
15 Effect of Thyroxin on NaCl Intake of Adrex Rats. 1963
15 Effect of TRH Upon I131 Update (I). 1973
15 Effect of TRH Upon I131 Update (II). 1973
15 Effect of Various Substance Treatment on the Thyroid Gland. 1953-1965
15 Effects of 2-Thio-6-Aminouracil (Raw Data). 1966-1967
15 Effects of 2-Thio-6-Aminouracil (Reduced Data). 1966-1967
15 Effects of 5-Carboxy-2-Thiouracil Experiments. 1966
15 Effects of Captopril and Bradykinin on Tail Skin and Colonic Temperature. 1994
15 Effects of Captopril and Bradykinin on Tail Skin and Colonic Temperature. 1994
15 Effects of Chlorothiazide and Hydrochlorothiazide on Thyroid Weight Ratios. 1958-1965
15 Effects of Enovid on Blood Pressure of Rats. 1971
15 Effects of Iproniazid on Action of Reserpine-CCR. 1960
15 Effects of Varying Concentrations of Resorcinol. 1973-1974
15 Effects of Water Temperature on Water Intake of Dehydrated Dogs. 1980
15 Effects of Water Temperature on Drinking in Female Dehydrated Rats. 1975
15 Efficiency of SC-6584 in Reducing Blood Pressure by Reducing Adrenal Function. 1957-1959
15 Electrical Recording of Rapidly Occurring Events in Man. Circa 1958
15 Encap Ca Study. 1985-1989
15 Encap - Tryptophan and Ca. 1986
15 Encapsulated Rate Oxygen Consumption. 1959
15 Enovid-Activity Experiment (NASA Building). 1968-1969
15 Enovid Balance Study (Adrex Rats). 1972
15 Enovid Experiment - Testicular Weight (NaCl Intake). 1970-1972
15 Enovid Female Rats - Salt Specificity Experiments. 1972
16 Enovid Hypertension. 1970-1971
16 Enovid - Hypertension and Salt Appetite (Female Rats). 1970-1972
16 Enovid - Hypertension Experiment #3. 1970
16 Enovid - Infusions of Epi Norepi and Angiotensin. 1972
16 Enovid - Normal Female Rats. 1973-1974
16 Enovid Running Activity - Ovariectomized Rats. 1969-1970
16 Enovid Running Experiment. 1970-1971
16 Enovid Sleeping Time. 1968
16 Established Hypertensives - Thyroid Cell Height. Not Dated
16 Estradiol Benzoate - Effect on Isoproterenol (Induced Drink). 1976
16 Estradiol Benzoate Rats. 1977-1978
16 Estradiol Measurement. 1983-1984
16 Estrogen - Catecholamines. 1983-1984
16 Estrogen Hypertension. Not Dated
16 Estrogen T4 and T3. 1977-1979
16 Estrogen-Treated Isoproterenol Drink. 1979
16 Estrogen Treated Rats. 1984
16 Estrone-PTU Experiments. 1963-1964
16 Ethynyl Estradiol (EE). 1976-1979
16 Ethynyl Estradiol and Distilled Water on Rats. 1976
16 Ethynyl Estradiol Tube Rats. 1976
16 Experiment #105 DOCA Salt Kynurenic Acid Nyacinamide. 1992
16 Experiment - et 1 oz. AII Drinking. 1992
16 Experiment on Effect of Sodium Chloride on Metabolic Rate of Rats. 1967
16 Exposure of Normal Diet and PTU-Treated Rats to Cold. 1960
16 Factors Affecting NaCl Intake. 1964-1994
16 Factors Affecting Spontaneous NaCl Appetite. 1971
16 Fat Diet Studies. 1973-1974
16 Fat Diet Studies. 1973
16 Fat Diet Studies. 1978
16 Fat Diet Studies - Summaries. 1974
16 Fecal and Urinary Thyroxine I131. 1966
16 Fecal Experiments 3-4 (Na and K). 1969
16 Feces Na and K Concentrations (Cold-Altitude Experiments). 1972-1973
16 Fenfluoramine Study. 1986-1987
16 Field DDD and Ethionine. 1966
16 First Adrex-Aldosterone Experiment (0.1, 0.5, 1.0, and 5 mg). 1963
16 Fluid Intakes I131-Treated - Jacobson. 1958
16 Glucose Determination. 1974
16 Glucose Load Study and AII (File 1). 1992
17 Glucose Load Study and AII (File 2). 1992
17 Glucose Load Study and AII (File 3). 1992
17 Glucose Load Study and AII (File 3 - continued). 1992
17 Glucose - NaCl Taste Interaction. 1969
17 Glucose - NaCl Taste Interrelationship. 1969
17 Glucose Study (Control Rats). 1977
17 Glycerol Solution in the Prevention of Hemorrhagic Shock. 1992
17 Graded NaCl Intake on Drinking. 1986
17 Graphs from Various Experiments. Not Dated
17 Growth Hormone and Exposure to Cole. 1958-1960
17 Growth Hormone Papers. 1956-1958
17 Guinea Pigs - Blood Pressure Experiment 1. 1965
17 Guinea Pigs - Blood Pressure Experiment 2. 1966-1967
17 Guinea Pigs - Blood Pressure Experiment 3 (Thyroxine-Hypertension). 1966-1967
17 HCZ (Hydrochlorothiazide) - Taste Threshold. Not Dated
17 HCZ DOCA Experiment - Adrex Rats. 1966-1985
17 HCZ - Effect on NaCl Intake Write Up. 1961-1967
17 HCZ Experiment - Sodium Balance. 1966-1967
17 HCZ - KCl Intake Experiments. 1966
17 HCZ - NaCl Intake Experiments. 1965
17 HCZ on Thyroxine I131 Experiment 1. 1965-1967
17 HCZ on Thyroxine I131 Experiment 4. 1964-1966
17 HCZ on Thyroxine Excretion. Not Dated
17 Heat Experiments. 1957
17 Heat Experiments. 1957-1959
17 Heat Experiments (Aldosterone and DOCA). 1957-1959
17 Heat Induced Drinking. 1989-1991
17 Heat Output and Weight Loss During Fasting in Steroid-Treated Rats. 1974
17 Heat Production - Heat Loss Experiments on Maltose Rats. 1974-1976
17 Heating Experiments. 1957
17 Hibernating Ground Squirrel Study. 1951
17 Hibernating Hamster Data. 1951
18 Hood - Sprague Dawley - Drink. 1989-1990
18 Hood - Sprague Dawley - NaCl Preference Threshold. 1989-1991
18 Hooded Female Rats Ca Deficiency Diet. 1958
18 HTP on TST (Tail Skin Temperature) - 8H-DTAT, Metergoline (1). 1980-1994
18 HTP on TST (Tail Skin Temperature) - 8H-DTAT, Metergoline (2). 1993-1994
18 HTP on TST (Tail Skin Temperature) - 8H-DTAT, Metergoline (3). 1993-1994
18 Hydrochlorothiazide Experiment 3 - NaCl Intake. Not Dated
18 Hydrochlorothiazide Experiment 7. 1963-1964
18 Hydrochlorothiazide - Iodide Deficiency Experiments. 1961
18 Hydrochlorothiazide (HCZ) Taste-Threshold Experiment (Deborah Leigh Giles). 1966
18 Hydrodiuril and Aldactone Experiment 5. 1960
18 Hydroxytryptamine and DUP 753 Serotonin. 1993
18 Hyperhydrating Effects of Angiotensin II. 1991
18 Hyperhydration - AII and NaCl Loads. Not Dated
18 Hyperhydration and Tolerance to Heat. 1991-1992
18 Hyperhydration - Hooded Rats Angiotensin I and II. 1991
18 Hyperhydration - NaCl Solution. 1991-1992
18 Hyperhydration Study. 1992
18 Hypertension and Cold Exposure. 1974
18 Hypertension - High Fat. 1982
18 Hypertension - I131 Uptake and Release Experiment 5. 1969
18 Hypertension - I131 Uptake and Release Experiment 6. 1969
18 Hypertension in Hypox Rats. Circa 1959
18 Hypertension - NaCl, Water Intake. 1979
18 Hypertension - Thyroxine I131 Study. 1967
18 Hypertensive Rats. 1952-1956
18 Hypertensive Rats - Blood Pressure Enovid Experiment). 1969-1970
18 Hypertensive Rats - Release Rate Study. 1971-1972
18 Hypertensive Rats - Systolic Blood Pressure. 1971
18 Hypophysectomized Rats and AII Study. 1992
19 Hypophysectomized Rats. 1985-1988
19 Hypophysectomized Rats. 1985
19 Hypothyroidism and Heat Tolerance. 1959
19 Hypothyroidism - Isoproterenol Tail Temperature Studies. 1974
19 Hypothyroidism on Maintenance of Body Temperature. 1957
19 Hypox and ACTH Coding Tests Body Cuts Over 100 gms. 1959
19 Hypox - Angiotensin Thyroid Effect - Salt Appetite. 1963-1964
19 Hypox - Angiotensin. 1964
19 Hypox - Angiotensin Experiment. 1964-1971
19 Hypox - Angiotensin (Last Experiment). 1971
19 Hypox - Combined DOCA-NaCl Intake Experiments. Not Dated
19 Hypox - DOCA, NaCl Appetite Experiment 1 (Aldosterone). 1964-1966
19 Hypox - DOCA, NaCl Appetite Experiment 3. 1970
19 Hypox - Norethynodrel. Circa 1971
19 Hypox - Pitressin. 1968-1971
19 Hypox Rats. 1985-1988
19 Hypox Rats - Cortisone Acetate on Glucose Intake. 1964-1965
19 Hypox Rats - Ethynyl Estradiol. 1968-1971
19 Hypox Rats - Experiment 2 (M. Dekle). 1964-1966
19 Hypox Rats - PTU. 1960-1962
19 Hypox Rats - Urine Collections, PTU). 1958-1959
19 Hypox - Renin and Pitressin. 1966
19 Hypox - Salt Appetite (Testosterone). 1968-1971
19 Hypox - Salt Hypertension Study 3. 1959-1960
19 Hypox - Summary Tables. Circa 1971
19 Hypox - Thyroid Experiment. 1961-1962
19 I131 Release from Rats. 1962
19 I131 Release Rate Study. 1972
19 I131 Thyroid Whole Body Uptake Study. 1972-1974
19 I131 Uptake Within the First Eight Hours After Injection. 1973
19 Indomethacin Drink Experiment on Isoproterenol Drink. 1977-1980
19 Indomethacin Study. 1992
20 Insulin - Normal Rats. 1966
20 Intake Study of Purina Chow, Na Deficient Food and Na Deficient Food with 4% NaCl. Circa 1978
20 Intake Study of Purina Chow, Na Deficient Food and Na Deficient Food with 4% NaCl (Group Data). Circa 1978
20 Intake Study of Purina Chow, Na Deficient Food and Na Deficient Food with 4% NaCl (Individual Study). Circa 1978
20 Intake Study for Thyroxin Threshold. 1971-1973
20 Intestinal Smooth Muscles. 1955-1956
20 Intraperitoneal and Intragastric Load on Drinking. 1985-1992
20 Iodide Electrode - Data (Includes Journal Articles and Notes). 1969-1971
20 Iodide Electrode - Varying Iodide Concentrations on Lactoperoxidase Reaction. 1971-1974
20 Iodide Electrode - Varying Iodide Concentrations of H2O2 on Lactoperoxidase Reaction. 1976
20 Iodination of AII. 1990
20 Iodine Deficiency Experiment 9. 1957-1958
20 Iodine Deficient Diet - Encap Rats. 1979
20 Iodine - Low Iodine TDF Experiments on Rats. 1971
20 Isopropyl Sodium Carboxylate Sydnone. 1962
20 Isoproterenol - Angiotensin II Interaction. 1978-1982
20 Isoproterenol Drink - Effect of Propanolol, Practolol. 1974-1975
20 Isoproterenol Hyperhydration. 1991-1992
20 Isoproterenol Hyperhydration. 1991
20 Isoproterenol Study on Tail Skin Temperature. 1992
20 Isuprel Studies - Tail Temperature. 1971
20 K Deficiency and Supplemental Diets. 1960
20 KCL Experiment. 1962-1963
20 KNO3 and DOCA Treated Rats. 1960-1961
20 L-5-Hydroxytryptophan and Distilled Water Load. 1980-1993
20 L-5-Hydroxytryptophan in the Rat (Mini-Pump Study). 1980
20 L-5-OH Tryptophan. 1979-1985
20 L-5-OH Tryptophan Atropine SO4. 1980
20 L-Thyroxine. 1961-1962
20 L-Thyroxine Injection. 1941-1969
20 Lactic Acid Experiments (Days 1-4). 1991
20 Lactic Acid Experiments (Days 5-8). 1991
20 Lactoperoxidase System (Resorcinol and Iodide). 1973-1974
20 Lesion and Renal Encapsulated Rats. 1977-1978
20 Lesion and Renal Encapsulated Rats. 1977-1978
20 Lesion Diuresis. 1966
20 Lesioned Rats. 1980
20 LiCl Experiment. 1957
20 Liquid Diet Cold. 1990
21 Lithium and Aldomet on Drinking Response to Isoproterenol (Includes Journal Articles). 1969-1976
21 Liver Powder. 1963
21 Locus Coerulens Lesion Study. 1979
21 Low Dose of O,P-DDD on the Development of Hypertension. 1963
21 Low Sodium Dietary Study. 1986-1987
21 Male Encapsulated Hypertensive Study 3B. 1967
21 Maltose - Oral Contraception. 1974
21 Maltose Taste Threshold (Estrogen-Treated Rats). 1976
21 Medroxy Progesterone Intake Experiment. 1973
21 Metabolic Responses to Heat. 1966-1967
21 Methazolamide I131. 1963-1966
21 Methazolamide - NaHCO3 Intake. 1965-1966
21 Methylphenidate. Circa 1963
21 MK-421 (Water Intake, Dehydration). 1981-1982
21 Mouse Salivary Gland Experiment. 1972-1973
21 Mouthwash Data. 1979
21 Na and K Balance Diet Study. 1975
21 Na Balance (Adrex and Control). 1965-1966
21 Na Balance (Control). 1966
21 Na Balance (Control). 1966
21 Na Balance (Hypothalamic Lesion and Control). 1966
21 Na Balance (Normal). Circa 1965
21 NaCl and Vasopressin Study. 1992
21 NaCl and Water Intake I-Treated Rats (Winona Experiments 1-3). 1958-1959
21 NaCl Appetite of PTU-Treated Rats. 1961
21 NaCl Intake and Diuresis Studies. 1976
21 NaCl Intake Experiment 1. 1964-1965
21 NaCl Intake - Hypertensive Rats. 1955
21 NaCl Intake - Hypertensive Rats (Aldactone, DOCA). 1964-1966
21 NaCl Intake - Hypertensive Rats (Effect on PTU). 1957
21 NaCl Intake on Female Blue Spruce Adrex and DOCA. 1975-1976
21 NaCl vs. Na2CO3 Intake. 1981
21 NaCl Water and Food in Tapazole and Thiouracil Diet Rats. 1959
21 NEFA Data and PBI Data Summaries - TDF Extractions. Not Dated
21 Niacinomide. 1992
22 Nicotinamide (Ora's Old Rats). 1986-1987
22 Nicotine Study. 1981-1982
22 Nicotinic Acid - DOCA Hypertension. 1986
22 Nicotinic Acid - Normal Rats. 1986
22 Nicotinic Acid Study II (Folder 1 of 2). 1986-1987
22 Nicotinic Acid Study II (Folder 2 of 2). 1986-1987
22 Norethynodrel - Effect on NaCl Intake in Intact and Adrex Rats. 1972
22 Norethynodrel - Tube Implants. 1972
22 Octopamine (Clyde Williams). 1977-1983
22 O,P'-DDD Experiment 3. Circa 1962
22 O,P'-DDD Experiment 4. Circa 1960-1962
22 O,P'-DDD Experiment 5. Circa 1961
22 O,P'-DDD Experiment 6. 1961-1968
22 Oral Contraceptive - Salt Appetite Tables. Circa 1976
22 Orchidectomy Experiment. 1959-1962
22 Osmolarity Experiments. 1967-1979
22 Osmolarity PTU-Treated Rats. 1959-1960
22 Ovariectomy - Class Experiment. 1959-1962
22 Ovex-DOCA-Estrogen and Hypertension. Not Dated
22 Oxygen Concentration and Bath Temperature for Ovex and Tube Rats. 1977
22 Oxygen Concentration in Warm Water. 1958-1959
22 Oxygen Concentrations and Colonic Temperature for EE10, EE20 Control Rats. 1977
22 Oxygen Concentrations and Heat Loss Studies. Not Dated
22 Oxygen Consumption. 1994
22 Oxygen Consumption (2). 1994
22 Oxygen Consumption (3). 1994-1995
23 Oxygen Consumption and Heat Changes During Cold Exposure. 1974
23 Oxygen Consumption During Cooling (PTU vs. Control). 1959
23 Oxygen Consumption in 10 Degrees Celsius Water (Adrex Rats). 1959
23 Oxygen Consumption PTU-Treated and Normal Rats. 1959-1960
23 Oxygen Consumption Study. Not Dated
23 PBI Results (Wet Ashing Method). 1967-1970
23 Phentolamine AII and Saline Study. 1984-1992
23 Phenylephrine and Norepinephrine on Tail Skin and Colonic Temperature (in Rats). 1976
23 Post-Cold Drink - Central Captopril. 1983
23 Post-Cold Drink (Sprague Dawley). 1978-1989
23 Post-Cold Drink (Sprague Dawley). 1981-1989
23 Post-Cold Drinks (Water Loads). 1980
23 Potassium Gluconate - NaCl Appetite (Normal Rats). 1964-1966
23 Preference Threshold, Enovid Treated Hooded Rats. Not Dated
23 Pregnancy Studies. Circa 1953-1954
23 Preventing Hypertension with Sulfaminouracil and CoCl2. 1963-1964
23 Progesterone Hypertension III. 1975
23 Progesterone - Hypertensive Rats. 1975
23 Propranolol and Butoxamine. 1981
23 Propranolol in Isoproterenol and Phenylephrine on Tail and Colonic Temperature. 1974
23 Propranolol on NaCl Appetite. 1983-1984
23 Propranolol, Practolol and Butoxamine on Post Cold Drinking. 1976-1977
23 Propranolol Study. 1984
23 Propranolol Test Rats (Effect of Various Amounts of AII). 1992
23 Protein Bound Iodine (PBI) Determination. 1958
23 PTU - Activity Experiment 2. 1958
23 PTU - Aldosterone (NaCl Appetite) Angiotensin - DOCA. 1965
23 PTU and Theophylline. 1967
23 PTU and Thyroxine on Testicular Hypertrophy. 1963
23 PTU - Angiotensin, Aldosterone, Pitressin Tannate. 1965
23 PTU - DOCA Angiotensin. 1967
23 PTU - DOCA Taste Threshold. 1968
23 PTU - Effect on NaCl Appetite of Adrex Rats. 1959
24 PTU - HCG (Padgett). 1959-1960
24 PTU - Heat Exposure. 1963
24 PTU - Hypertension Experiments 1-4. 1956-1957
24 PTU - Hypertensive Experiment 5A. 1957
24 PTU - Na Balance Study. 1958
24 PTU - Na Balance #2 Dehydration Experiment. 1959
24 PTU - Na Balance #3. 1959
24 PTU - Na Balance #4. 1959
24 PTU - Na Balance #5. 1961
24 PTU - Na Balance #6. 1961
24 PTU - Na Deficiency Study. 1965
24 PTU - NaCl Appetite (Estone Corticosterone Renin). 1964-1965
24 PTU - Normal Rats Experiment 5. 1957
24 PTU, Pitressin and Oxytocin Study. 1966
24 PTU Taste Threshold 1-2. 1964-1968
24 PTU Thiouracil Treatment Male and Female Experiment 6. 1957
24 PTU-Treated Rats (Correspondence Included). 1959
24 PTU-Treated Rats NaCl Intake (Effect of Angiotensin, Pitressin, Aldosterone). 1964-1965
24 PTU - Urea Taste Threshold. 1965
24 Pyridoxal Phosphate and Pyridoxine HCl Study. 1987-1988
24 Quinolic and Anthranilic Acids. 1987
24 Quinolic and Anthranilic Acids. 1987
24 Rabbit Ear Temperature. 1993
24 Radioactive I131 Release Rate Study - Body Count. 1972
24 Radioactive I131 Release Rate Study (I). 1972
24 Radioactive I131 Release Rate Study (II). 1972
24 Rat Dehydration (24 Hours Dehydration). 1959
24 Rats Treated with Pilocarpine and Bethanechol. 1980-1982
24 Reduced B-Adrenergic Responsiveness in Rats. 1974
24 Regression Program. 1967
24 Relationship Between Blood Pressure and Organ Weight in Rats. 1961-1962
24 Renal Encap Rats (CPP - S-720-22, 5 CHTP). 1966
24 Renal Encap Rats (Includes Journal Articles). 1974
24 Renal Extractions Thyroid Slice Incubation. 1968-1969
24 Renal Factor - Effect of Rat Renal Extract on Blood Pressure of Hypertensives. 1969-1970
24 Renin and Angiotensin on Thyroid Gland. 1960-1961
24 Renin Activity in Hypertensive Rats (Plasma). 1981
24 Renin Angiotensin Aldosterone. 1958-1984
25 Renin - Cold-Treated Rats - Drinking Response. 1976
25 Research Ideas on Cold. Not Dated
25 Research Proposals, U.S. Army Medical Research and Developmental Command. 1968
25 Responsiveness to Dipsogenic Stimuli in Rats. 1975-1976
25 Results and Notes from Experiments on Jacobson Rat. 1958-1959
25 Role of Adrenal Glands in Renal Hypertension. Circa 1956
25 Running Activity Experiment 3. 1972
25 Running Activity (Experiment on PTU Treated Rats). Not Dated
25 Salivariectomized Rats. 1975
25 Salivary Gland (Research Done in University of Alabama). Not Dated
25 Salivary Na Concentration and DOCA in Adrex Rats. 1964
25 Salivary Na - NaCl Intake, Hypertensive Rats. 1977-1980
25 Salt Appetite, Adrex - Cortisone and DOCA (Class Experiment - MED 521). 1971-1972
25 Salt Appetite - Angiotensin III. 1977
25 Salt in Diet Study. 1981
25 Salt Intake I131-Treated Rats. Not Dated
25 Salt Intake (Normal Rats) - DOCA, Aldosterone, Angiotensin. 1964-1968
25 Salt Intake Regulation. 1955-1962
25 Salt Intake Regulation. Circa 1958
25 Salt Intake Tapazole-Treated Rats. 1959
25 Salt-Resistant and Salt-Sensitive Experiments. 1989
25 Salt Solution Intake PTU Treated Adrex Rats. Not Dated
25 Salt Specific Experiment. Not Dated
25 Saralasin Isoproterenol Study. 1984-1992
25 SAU-720-22 and HCZ in Food Diuresis Study. 1966
25 SC 8109 and Aldactone Experiment 4. 1960-1961
25 Secondary Butyl Sydnone - Control Rats. 1962
25 Secondary Butyl Sydnone - Diuresis. 1962
25 Serum Cholesterol Determination. 1957-1962
25 SHR - 1.5 and 3.0% Tryptophan. 1988
25 SHR - 1.5 and 3.0% Tryptophan. 1988
25 SHR - 5-HTP. 1988
25 SHR - Tryptophan (Folder 1 of 2). 1986-1987
25 SHR - Tryptophan (Folder 2 of 2). 1986-1987
26 SHR - Tryptophan Study. 1986-1987
26 SHR - Tryptophan Study. 1986-1988
26 SHR - Tryptophan Study Using Isoproterenol (Oxygen Consumption). 1987
26 Sodium and Chloride Electrode. 1984-1985
26 Sodium and Potassium Exchange in Adrenalectomized Rats as Affected by Desoxycorticosterone Acetate. Not Dated
26 Sodium and Potassium Exchanges in Adrenalectomized Rats. 1968
26 Sodium Balance Experiments. 1957
26 Sodium Balance Experiments Part I. 1957
26 Sodium Balance Study. 1957
26 Sodium Balance Study. 1957
26 Sodium Electrode vs. Flame Photometry. 1967-1968
26 Sodium Lactate Study. 1991
26 Sodium Nitrate - Blood Pressure. 1961-1962
26 Sodium Saccharin Experiment. 1957
26 Spiperone and Hypertonic Saline-Induced Drinking. 1978-1980
26 Spironolactone Experiment - Hood Rats Given Enovid. 1973
26 Spironolactone Taste Experiment. 1960
26 Spontaneous Hypertensive Male Rats (Group 1). 1970-1971
26 Spontaneous Hypertensive Male Rats (Group 2 - Born Here). 1971
26 Spontaneous Hypertensive Male Rats (Group 3). 1970-1971
26 Spontaneous Hypertensive Rats. 1973-1974
26 Spontaneous Hypertensive Rats - Thyroxine I131. Not Dated
26 Spontaneous Salt Intake - Thiouracil (Normal Rats). 1960
26 Statistics - Fitness Index, Cold Pressor Test. 1947-1954
26 Study of Adrex and Hypox Rats. 1959-1960
26 Study of Adrex Male Rats with Various Doses of DOCA. 1979
26 Study of Adrenalectomized Rats. 1979
26 Study of Aldosterone and DOCA on Hypertensive Rats. 1957
26 Study of Effect of O,P-DDD on Normal Rats (Experiment 1). 1962-1963
26 Study of Effect of O,P-DDD on Normal Rats (Experiment 2). 1962-1963
26 Study of Effect of Sodium Deficient Diet. Not Dated
26 Study of Effect of Sydnones. Not Dated
26 Study of Effects of AII DOCA - Estrogen (1). 1987-1989
26 Study of Effects of AII DOCA - Estrogen (2). 1987-1989
26 Study of Effects of AII DOCA - Estrogen (3). 1987-1989
26 Study of Effects of Benzolamide. 1986-1987
27 Study of Effects of Deserpine. 1961
27 Study of Levels of Sodium and Potassium in Rats. 1970-1970
27 Study of SU-4885 on Encap Rats. Not Dated
27 Study of T-Butyl-Methyl-Methypseudo Oxatriazole. 1962
27 SU-4885 and Piperidyl Sulfamic Acid. 1962-1963
27 SU-4885 NaCl Intake Normal Rats Experiment 1. 1966
27 SU-4885 NaCl Intake Normal Rats Experiment 2. 1966
27 Substance P (Nerve Growth Factor). 1981
27 Sulfamic Acid Experiment 3. 1963
27 Summary of Data - Thyroid Studies. Not Dated
27 T4 - Secretion Rate of Hypertensive Rats Experiment 3. 1968
27 T4 - Secretion Rate of Hypertensive Rats Experiment 4. 1969
27 Tail Skin and Colonic Temperatures of Rats Treated with Isuprel or Chlorohydrate. 1976
27 Tail Skin Temperature (1). 1992
27 Tail Skin Temperature (2). 1992
27 Tail Skin Temperature - Cold Treated. 1975-1976
27 Tail Skin Temperature Experiment. 1984-1992
27 Tail Skin Temperature Experiment (Angiotensin II). 1984-1991
27 Tail Skin Temperature Experiment (Angiotensin II). 1984-1993
27 Tail Skin Temperature Experiment (Angiotensin II). 1984-1992
27 Tail Skin Temperatures - T4 and Isuprel. Not Dated
27 Tail Temperature - Chronic Dose of Propanolol in Rat Diet. Not Dated
27 Tail Temperature - Vasopressin. 1990
27 Tapazole in Established Hypertension Experiment 7. 1958-1959
27 Tapazole Study on Dog. 1960
27 Taste Threshold Experiment (Spontaneous Hypertensive - Enovid Treated). 1970-1971
27 Taste Threshold - Male vs. Female Rats. 1972
27 Taste Threshold - Oral Contraceptive. 1970-1971
27 Taurine and Indoleacetic Acid Study. 1990-1996
27 Taurine - DOCA Hypertension. 1990-1994
28 TDF (Thyroid Depressing Factor) Analyzed Experiments (Statistically). 1962-1972
28 TDF Effect on Blood Pressure. 1980
28 TDF Body Count. 1972
28 TDF Effect - Radioactive Iodine Release Rate. 1972
28 TDF Effect on Urinary Na and Water Loss. 1984
28 TDF Effect on Water Intake. 1978
28 TDF Natriuretic Effect. 1985
28 TDF Preps. 1969-1970
28 TDF and Tyrosine. 1973
28 TDF In Vivo Study. 1973
28 Temperature Regulation Experiments. 1956-1958
28 Testosterone Castration Experiment. 1978
28 Testosterone Experiments (Castrated and Intact Rats). 1978-1979
28 Thiosuccinic Acid, Theophylline, O,P'-DDD (Hypertensives). 1952-1963
28 Thirst After Removal from Cold. 1970
28 Thirst in Hypertensive Rats. 1975
28 Thirst in Spontaneously Hypertensive Rats. 1976
28 Thyrex-Encap Female Rats Experiment 10. Not Dated
28 Thyroid and Hypertension Experiment 1. Circa 1959
28 Thyroid and Hypertension Experiment 2. Circa 1959
28 Thyroid and Its Effect on Hypertension. 1958
28 Thyroid and Kidney Study (TDF). 1977
28 Thyroid Depressing Factor (TDF). 1975-1982
28 Thyroid Depressing Factor (TDF). 1970-1971
28 Thyroid Depressing Factor (TDF). 1970-1971
28 Thyroid Depressing Factor (TDF). 1970-1972
28 Thyroid Depressing Factor (TDF). 1971
28 Thyroid Gland (High School Student Project). 1973
28 Thyroid Hypertension Summary. 1968-1970
28 Thyroid-Kidney Interrelationship. 1974
28 Thyroid Slice Data. Circa 1968
28 Thyroid Slices. 1968
28 Thyroidectomized Female Rats. 1957-1958
28 Thyroidectomy and Adx. Not Dated
28 Thyroidectomy of Established Hypertensive Rats. 1958
28 Thyroidectomy of Established Hypertensive Rats Experiment #11. 1958
28 Thyroxine Analogs. 1962-1966
29 Thyroxine I 131 Excretion in Hypertensive Rats 1-2. 1966
29 Thyroxine on Salt Intake - Rats. 1961-1962
29 Thyroxine - PTU-Treated Rats. 1962-1963
29 Thyroxine Secretion Rate Hypertensive Experiment 1. 1967-1969
29 Thyroxine Secretion Rate Hypertensive Experiment 2. 1968-1969
29 Thyroxine Secretion Rate of Hypertensive Rats. 1968
29 TQII (Thirst Quencher 2) Hyperhydration. 1992
29 Tryptophan Analog Study. 1988-1999
29 Tryptophan and L-5 Hydroxytryptophan Study. 1986
29 Tryptophan and Nicotinic Acid. 1986-1987
29 Tryptophan and P-HCl Study. 1988
29 Tryptophan - Captopril. 1989
29 Tryptophan - Captopril Study 1. 1989
29 Tryptophan - Captopril Study 2. 1989
29 Tryptophan - Captopril Study 3. 1989
29 Tryptophan - Captopril Study 3. 1989
29 Tryptophan Experiment (Ora Lockley) Folder 1 of 3. 1985
29 Tryptophan Experiment (Ora Lockley) Folder 2 of 3. 1985
29 Tryptophan Experiment (Ora Lockley) Folder 3 of 3. 1985
29 Tryptophan - Renal Hypertension. 1986
29 Tryptophan Study. 1979
29 Tube Implanted Spontaneous Hypertensive Rats - Progesterone. 1973
29 Tyrosine and DOCA Hypertension. 1985-1986
29 Tyrosine and Hypertension. 1980-1982
30 Tyrosine and Tryptophan. 1979
30 Tyrosine Hypertension Study. 1982
30 Tyrosine on Renal Hypertensive Rats. 1981-1984
30 Tyrosine Study. 1986
30 Unilateral Nephrectomy. 1985
30 Unilateral Nephrectomy Experiment. Not Dated
30 Urea and KCl. 1958-1959
30 Urea Threshold - Hypertensive vs. Normal Rats. 1957-1965
30 Urinary Glucose Concentration in the Rat. 1976
30 Urine and Fecal I131 Analysis. 1964
30 Urine Experiments 3-4 (Na and K - Altitude). 1969
30 Valine Experiments (Body Weight and Blood Pressure). 1989
30 Valine Study. 1991-1994
30 Vasopressin, AII, DUP Study - Experiment 1 (Response Curve Study). 1990-1991
30 Vasopressin, AII, DUP Study - Experiment 2 (AII and Vasopressin). 1990-1991
30 Vasopressin, AII, DUP Study - Experiment 3 (AII and V-Blocker). 1990-1991
30 Vasopressin, AII, DUP Study - Experiment 4A (AII and DUP Blocker). 1990-1991
30 Vasopressin, AII, DUP Study - Experiment 4B (AII and DUP Blocker). 1990-1991
30 Vasopressin, AII, DUP Study - Experiment 5 (Vasopressin and V-Blocker). 1990-1991
30 Vasopressin, AII, DUP Study - Experiment 6 (Vasopressin and DUP Blocker). 1990-1991
30 Vasopressin, AII, DUP Study - Experiment 7 (Vasopressin and V-Blocker). 1990-1991
30 Vasopressin, AII, DUP Study - Experiment 8 (AII and DUP). 1990-1991
30 Vasopressin, AII, DUP Study - Experiment 9 (Vasopressin and V-Blocker). 1990-1991
30 Vasopressin and V-Blocker Study. 1990-1991
30 Vitamin B12 Experiment 1. 1957
30 Vitamin B12 Experiment 2. 1957
30 Vitamin B12 Experiment 3. 1957
30 Vitamin B12 Experiment 4. 1958-1959
30 Vitamin B12 Experiments Summary. 1958
30 Water and Food Intake of Rats Treated with Substance P. 1991
30 Water and Food Intake (Temperature, Thermogenic Drinking). 1974-1975
30 Water vs. NaCl Intake. 1985-1986
30 Whole Body vs. Thyroid I131 Release Rate (I). 1972
30 Whole Body vs. Thyroid I131 Release Rate (II). 1972
30 Yohimbine and Isoproterenol on Drinking. 1980-1982


Cold Research 1951-1995

This series includes materials related to Fregly's research of cold, altitude, and cold-induced hypertension. The folders in this series were filed separately from the other research files in this collection and each folder was labeled as a "Cold" file. It should be noted, however, that additional cold research files can be found in the other series in this collection. The majority of the files in this series pertain to a sequence of numbered experiments conducted by Fregly and his assistants.


Box
31 Activity in Cold for Normal and PTU Treated Rats. 1959
31 Cold Adaptation - Dose Response Study. 1979
31 Cold and Altitude Experiment 3-4. 1969
31 Cold and Altitude Experiment 5. 1970-1973
31 Cold and Altitude Experiment 5 (Fecal Na and K). Circa 1972
31 Cold and Altitude Experiment 6. 1972
31 Cold and Altitude Experiment 6. 1973
31 Cold and Altitude Experiment 7 (Food Analysis). 1972
31 Cold and Altitude Experiment 7. 1973
31 Cold and Altitude Experiment 8. 1973
31 Cold and Altitude Experiment 8. 1973
31 Cold and Altitude Experiment 9. 1973
31 Cold and Altitude Experiment 9. 1973-1974
31 Cold and Altitude Experiment 9 (Feces Digestion). 1973
31 Cold and Altitude Experiments (Food vs. Water Intake and Urine vs. Water Intake). 1970
31 Cold and Altitude Experiments (Organ vs. Body Weights). 1972-1973
31 Cold and Altitude Experiments (Osmolarity and Dehydration). 1969-1970
31 Cold and Altitude Experiments (Plasma and Urinary Osmolarity). 1972
31 Cold and Altitude Experiments (Series I-II). 1951
31 Cold and Altitude Experiments (Series III). 1951
31 Cold and Altitude Experiments (Serum and Dehydration Urine Osmolarity). 1969-1974
31 Cold and Altitude Experiments (Sodium and Potassium Balance) (1). 1973
31 Cold and Altitude Experiments (Sodium and Potassium Balance) (2). 1972
31 Cold and Altitude Experiments (Sodium and Potassium Balance) (3). Circa 1972
31 Cold and Altitude Experiments (Water Intake vs. Food Intake). 1965-1988
32 Cold Blood Pressure Study. 1981-1982
32 Cold Blood Pressure Study. 1983-1985
32 Cold Experiment #1 (Pilot Cold Study). 1986
32 Cold Experiment #1 (Response to Phenylephrine Isoproterenol and AII). 1987-1993
32 Cold Experiment #2 (Includes Data on Experiments 3 and 6). 1988-1989
32 Cold Experiment #3. 1988
32 Cold Experiment #3 (Urine Na and K). 1988-1989
32 Cold Experiment #6. 1988
32 Cold Experiment #6. 1988
32 Cold Experiment #7 (Organ and Body Weight, Tail, Blood Pressure). 1988
32 Cold Experiment #8 (Organ Weights - Rats). 1988
32 Cold Experiment #10 (K and Na in Urine). 1989
32 Cold Experiment #11 (Creatinine, K and Na Readings). 1989
32 Cold Experiment #12 (Direct Blood Pressure Data - Systolic, Diastolic, Mean). 1989
32 Cold Experiment #13 (Blood Pressure Calculated Data - Systolic, Diastolic, Mean). 1989
32 Cold Experiment #14 (Body Weight, Blood Pressure and Intake of Water, Food). 1989
32 Cold Experiment #15 (Cats - Water, NaCl, Food Intake). 1989-1991
32 Cold Experiment #15 (Raw Data - Indirect Blood Pressure). 1989-1990
32 Cold Experiment #15 (Indirect Tail Blood Pressure). 1989
32 Cold Experiment #16 (Catecholamine Outputs). 1990
32 Cold Experiment #16 (Catecholamine Outputs). 1990
32 Cold Experiment #16 (Catecholamine Outputs). 1989-1991
32 Cold Experiment #16 (Change in Food Intake Due to Cold). 1989
32 Cold Experiment #16 (Change in Food Intake Due to Cold). 1989
32 Cold Experiment #16 (P and Na Outputs, Food and Water Intakes). 1989-1990
32 Cold Experiment #16 (Post-Cold Intake and Output). 1989
32 Cold Experiment #17. 1989
33 Cold Experiment #19 (Creatinine Readings). 1989
33 Cold Experiment #22 (Creatinine). 1990-1991
33 Cold Experiment #25 (Creatinine). 1990-1991
33 Cold Experiment #27 (Creatinine). 1990
33 Cold Experiment #28 (Creatinine). 1990-1991
33 Cold Experiment #30 (DUP and AII Cold Study). 1990-1991
33 Cold Experiment #30 (DUP and AII Cold Study). 1990-1992
33 Cold Experiment #30 (DUP and AII Cold Study). 1990-1992
33 Cold Experiment #31 (Catecholamines in Organs). 1991
33 Cold Experiment #31 (Urinary Catecholamines). 1991
33 Cold Experiment #31 (Urinary Catecholamines). 1991
33 Cold Experiment #33 (Prazosin). 1992
33 Cold Experiment #34 (ATZ) (1). 1991-1994
33 Cold Experiment #34 (ATZ) (2). 1991-1992
33 Cold Experiment #34 (ATZ) (3). 1991-1992
33 Cold Experiment #34 (ATZ) (4). 1991-1992
33 Cold Experiment #34 (ATZ) (5). 1991-1992
33 Cold Experiment #34 (ATZ) (6). 1991-1992
33 Cold Experiment #35. 1990-1992
34 Cold Experiment #40. 1991-1992
34 Cold Experiment #41 (DOCA Salt Niacinamide). 1991-1992
34 Cold Experiment #103 (AII, Prazosin, L-Arginine). 1991-1992
34 Cold Experiment #103 (AII, Prazosin, L-Arginine). 1991-1992
34 Cold Experiment #103 (AII, Prazosin, L-Arginine). 1991-1992
34 Cold Experiment #105 (Creatinine). 1992
34 Cold Experiment #106 (Cold Study Uphill). 1993
34 Cold Experiment #109 (Urinary Electrolytes from Control, Cold and Warm Sessions). 1993
34 Cold Experiment #109 (Urinary Catecholamines from Cold Session). 1993
34 Cold Experiment #109 (Urinary Catecholamines from Control and Warm Sessions). 1993
34 Cold Experiment #109-2 (Cold, Food Intake). 1993-1994
34 Cold Experiment #109-2 (Losartan Study). 1994
34 Cold Experiment #110 (Renal Denervation). 1993
34 Cold Experiment #110 (Urinary Electrolytes). 1993
34 Cold Experiment #110 (Urinary Electrolytes). 1993
34 Cold Experiment #112 (Renal Denervation). 1993
34 Cold Experiment #112 (Urinary Electrolytes). 1993-1994
34 Cold Experiment #112 (Urinary Electrolytes). 1993-1994
34 Cold Experiment #117. 1992-1995
34 Cold Experiment #117 (Effect of Treatment with Pyridoxamine and Sulfaminouracil on Development of DOCA-Induced Hypertension). 1994
34 Cold Experiments. 1959
35 Cold Experiments. 1958
35 Cold Exposure. 1973-1974
35 Cold Hypertension. Not Dated
35 Colonic Cooling Rates - PTU, Adx and Skin Cooling Rates. 1956
35 Colonic Cooling Rates - Cortisone, Thyroxine. 1954-1956
35 Compiled Studies on Cold-Warm. 1994
35 Compiled Studies on Cold-Warm. 1994
35 Compiled Studies on Cold-Warm. 1994
35 Cooling Rate and Ca Excretion in Cold. 1978
35 Cooling Rates - Reserpine. 1957-1959
35 Deacclimatization Tests. 1951
35 Decrease in Isoproterenol Sensitivity. 1976
35 Effect of Cold on Urinary Concentrating Ability of White Rats. 1967-1971
35 Effect of Low Bulk Diet on Water and Electrolytes. 1967-1970
35 Effect of Low Bulk Diet on Water and Electrolytes. 1967-1970
35 Effect on Cooling Rate of Exposure to Cold (Every Other Day for Five Exposures). 1951
35 Evaporative Water Loss. 1953
35 Food Intake and Urine Osmolarity. 1977
35 Isoproterenol and Renin Sensitivity in Male and Female Rats. 1975-1976
35 L-Arginine. 1992
35 Oxygen Consumption at Cold (5 Degrees C) for PTU vs. Normal Rats. 1959
35 Repeated Exposures to Cold. 1951
35 Repeated Exposures to Cold (Every Second Day). 1951
35 Skin Cooling Tests - Normal, Adx, PTU. 1957-1959
35 Statistical Analysis Experiment 2 (Cold - Hypertension). Not Dated
35 Study of Rat Vitals During Exposure to Cold. 1952-1958
36 Summary of Cold Experiments #1. 1991-1992
36 Summary of Cold Experiments #2. 1990-1993
36 Summary of Cold Experiments #3. 1990-1993
36 Summary of Cold Experiments #4. 1990-1993
36 T-Tests Hypertension Cold Experiment. Not Dated
36 Test - Aldosterone. 1957
36 Water and Electrolytes During Cold. 1965-1975


Research Notebooks 1952-1956

Notebooks containing research data and notes related to experiments concerning altitude exposure, cold and hypertension, pregnancy, and the intake of sodium, water, and potassium.


Box
37 Altitude Book I. 1954
37 Altitude Book II. 1954
37 Continuous Exposure to Altitude (18,000 feet) Experiment III. 1955
37 Continuous Exposure to Altitude (18,000 feet) Experiment IV. 1955
37 Altitude Book Experiment V - Continuous Exposure. 1956
37 Experiment 2 - Effect of Cold on Hypertensive Rats. 1952
37 Experiment 2A, 2B, 2C, 2D, 2E, 2G, 2H, 2I (Activity Cages). 1952-1953
37 Experiment 7. 1954-1955
37 KCl Intakes (Na2SO4). 1955-1956
37 Na Free Diet and Measured Amount of Urea and Na and Water Intake in Hypertensive and Normal Rats. 1956
37 Pregnancy Study. 1954
37 Pregnancy Studies - Group J. 1954


Research Recording Charts (Heart Rate, Temperature, etc.) 1972-1986

Charts used to record blood pressure, heart rate, temperature, and other data during experiments pertaining to cold and altitude, ATZ, and tryptophan.


Box
38 ATZ Rats. 1975
38 ATZ Study - Blood Pressure and Heart Rate (8 chart bundles). 1974
38 ATZ Study - Heart Rate (2 chart bundles). 1975
38 Cold-Altitude Experiment (5 chart bundles). 1972
38 Cold-Altitude Study #7 (4 chart bundles). 1972
38 Cold-Altitude Study #8. 1973
38 Cold-Altitude Study #9 - Heart Rates. 1973
38 DOPA - Nicotinic Acid (2 chart bundles). 1986
38 EB Study (4 chart bundles). 1984
38 T4 Cholesterol (2 chart bundles). 1973
38 T4 Implant Study (Rats - ATZ) (2 chart bundles). 1973
38 Tail Temperature - Heart Rates (8 chart bundles). 1974
38 Tryptophan. 1986


Research Grants 1952-1998

This series is comprised of files pertaining to grant-funded research conducted or proposed by Fregly. The files contain grant applications, status reports, financial records, and correspondence related to the research projects. Topics include hypertension, the thyroid, oral contraceptives, salt preference and appetite, thirst and drinking, altitude and cold, and water and electrolyte exchange during exposure to cold.


Box
39 Adrenal Gland - Renal Hypertension. 1956-1959
39 Application for Training (Institutional Division of Genetic, Endocrinology and Metabolism). 1974-1979
39 Application - Brain Mechanisms of Drinking. 1986
39 Application - Brain Mechanisms of Drinking. 1986-1988
39 Application - Influence of Early Salt Diet on Taste and Blood Pressure. 1994
39 Application - Oral Contraceptive and Hypertension. 1971-1982
39 Application - Thermogenic Drinking in Cold-Adapted Rats. 1983-1985
39 Applications/Extensions - Oral Contraceptive. 1977-1982
39 Bio-Behavioral Aspects of Salt Appetite. 1985-1989
39 Bio-Behavioral Aspects of Salt Appetite. 1985-1987
39 Bio-Behavioral Aspects of Salt Appetite. 1986
39 Bio-Behavioral Aspects of Salt Appetite. 1986
39 Cardiovascular Research Training Grant. 1977-1978
39 Diuretics in Renal Iodide Excretion (Folder 1 of 2). 1966-1971
39 Diuretics in Renal Iodide Excretion (Folder 2 of 2). 1966-1971
39 Effect of Tyrosine on the Development of Hypertension. 1981-1989
39 Effect of Tyrosine on the Development of Hypertension. 1981-1986
39 Effect of Tyrosine on the Development of Hypertension. 1984-1988
39 Hormones, Neurotransmitters and Receptors in Cold and Heat. 1985-1986
39 Hypothalamic Pituitary Response to Stress (Includes Articles by Other Authors). 1952-1987
40 Metabolic Responses to the Stress of Oxygen at High Pressure. 1968-1972
40 National Science Foundation (Includes Research Proposal - Water and Sodium Intake). 1958-1959
40 Office of Naval Research (Includes Statements and Research Proposal - Post-Cold Drinking Phenomenon). 1969-1971
40 Office of Naval Research (Includes Invoice Statements and Research Proposal - Water and Electrolyte During Exposure to Cold and Altitude). 1966-1973
40 Oral Contraceptives and Hypertension. 1980-1984
40 Physiological Responses to Chronic Cold Exposure. 1986-1992
40 Physiological Responses to Chronic Cold Exposure. 1986
40 Physiological Responses to Chronic Cold Exposure. 1987-1998
40 Post-Cold Drinking Phenomenon in Rats. 1964-1965
40 Post-Cold Drinking Phenomenon in Rats (Folder 1 of 2). 1964-1969
40 Post-Cold Drinking Phenomenon in Rats (Folder 2 of 2). 1964-1969
40 Regulation of NaCl Intake by Rats. 1988-1989
40 Regulation of Sodium Intake by Hypertensive Rats. 1958
40 Regulation of the Brain Renin Angiotensin System. 1985-1986
40 Renal-Thyroid Interrelationship in Hypertension. 1972-1976
40 Renal-Thyroid Interrelationship in Hypertension. 1981-1985
40 Renal-Thyroid Interrelationship in Hypertension. 1981-1985
40 Research Proposal - Oral Contraceptives and Hypertension (National Science Foundation). 1971
40 Role of Hydration and Hyperhydration. 1990-1992
40 Role of Thyroid in Hypertension. 1970-1973
41 Role of Thyroid in Hypertension (Folder 1 of 2). 1960-1972
41 Role of Thyroid in Hypertension (Folder 2 of 2). 1960-1972
41 Salt Appetite (Folder 1 of 2). 1968-1971
41 Salt Appetite (Folder 2 of 2). 1968-1971
41 Stress, Sodium and Blood Pressure Regulation. 1987
41 Sulfur Compounds. 1962-1966
41 Thermogenic Drinking in Cold-Adapted Rats. 1982-1984
41 Thermogenic Drinking in Cold-Adapted Rats. 1980-1983
41 Thermogenic Drinking in Cold-Adapted Rats. 1980-1981
41 Water and Electrolyte Exchange During Exposure to Cold. 1972-1978
41 Water and Electrolyte Exchange During Exposure to Cold. 1974-1981
41 Water and Electrolyte Exchange During Exposure to Cold. 1968-1986
41 Water and Electrolyte Exchange During Exposure to Cold. 1983-1992
41 Water and Electrolyte Exchange During Exposure to Cold. 1986-1991
41 Water and Electrolyte Exchange During Exposure to Cold. 1987-1993
41 Water and Electrolyte Exchange During Exposure to Cold. 1989-1992
41 Water and Electrolyte Exchange During Exposure to Cold and Altitude (Folder 1 of 3). 1973-1983
41 Water and Electrolyte Exchange During Exposure to Cold and Altitude (Folder 2 of 3). 1973-1983
41 Water and Electrolyte Exchange During Exposure to Cold and Altitude (Folder 3 of 3). 1973-1983


Notes 1947-1976

This small series contains notes written by Fregly on topics such as hypertension, salt appetite, thirst, the thyroid, hormones, and general physiology. A few files contain Fregly's notes taken as a student in biochemistry, biology, and chemistry classes.


Box
42 Biochemistry 200. 1950-1951
42 Biology 203. 1947-1948
42 Chemistry 115. 1947
42 DDD Studies (Includes Correspondence). 1954-1965
42 Dopamine - Drinking. Not Dated
42 Early Concepts of Physiological Regulations (Dr. Edward F. Adolph). 1972
42 Electrical Fundamentals. 1964
42 General Notes, Primarily on Hormones. Not Dated
42 Growth Hormone. Not Dated
42 Hypertension. Not Dated
42 Kinnis, Kallekrein, Prostaglandins. Not Dated
42 Salt Appetite. Not Dated
42 Salt in the Human Body. 1962
42 Spontaneous Running Activity. Not Dated
42 Thirst Analog Models. 1957-1976
42 Thyroid and Altitude. Not Dated
42 Thyroid and Heat. Not Dated
42 Thyroid and Hypertension. Not Dated
42 Visualization of Cortical vs. Medullary Blood Flow. 1974
42 VO2 Apparatus. Not Dated


Publications and Writings 1949-1997

Comprised of journal articles, books, chapters, research reports, papers, and other writings created by Fregly, including his thesis and dissertation. Several files include correspondence, notes, and multiple drafts in addition to the final version of the publication. The topics covered by the writings correspond to the topics covered in the Research Files series. Frequent co-authors include J.R. Cade, N.E. Rowland, W.G. Luttge, M. Kare, C.M. Blatteis, and P.E. Tyler. The majority of the files contain journal articles and research reports, but the series also includes published monographs authored or contributed to by Fregly. In addition to the publications filed separately, it should be noted that this series includes several volumes, dated from 1953 to 1987, in which Fregly collected and bound his publications together in chronological order.


Box
42 Draft: Human Endocrinology: An Interactive Text (by Fregly and William G. Luttge). Circa 1982
43 Human Endocrinology: An Interactive Text (by Fregly and William G. Luttge). 1982
43 Seminar on the Role of Salt in Cardiovascular Hypertension (American Journal of Cardiology) (Fregly, Editor) - 4 copies. 1961
43 Journal of the Florida Medical Association ("Role of Chance in Discovery" by Fregly and Fregly). 1979
43 Acclimatization to Cold Atmospheres by Fregly (Partial Fulfillment of Requirements for Doctor of Philosophy Degree, University of Rochester). 1952
43 Role of Salt in Cardiovascular Hypertension (Edited by Fregly and Morley Kare). 1982
43 Biological and Behavioral Aspects of Salt Intake (Edited by Fregly, Morley Kare, Rudy Bernard). 1980
43 Oral Contraceptives and High Blood Pressure (Fregly and Marilyn S. Fregly). 1974
43 Handbook of Physiology: Section 4 - Environmental Physiology, Volumes 1-2 (Edited by Fregly and Clark Blatteis). 1996
43 Collected Publications of Melvin James Fregly, Volume 1. 1953-1962
44 Collected Publications of Melvin James Fregly, Volume 1. 1953-1962
44 Collected Publications of Melvin James Fregly, Volume 1. 1953-1962
44 Collected Publications of Melvin James Fregly, Volume 2. 1963-1967
44 Collected Publications of Melvin James Fregly, Volume 2. 1963-1967
44 Collected Publications of Melvin James Fregly, Volume 2. 1963-1967
44 Collected Publications of Melvin James Fregly, Volume 3. 1968-1972
44 Collected Publications of Melvin James Fregly, Volume 3. 1968-1972
44 Collected Publications of Melvin James Fregly, Volume 3. 1968-1972
44 Collected Publications of Melvin James Fregly, Volume 4. 1973-1977
44 Collected Publications of Melvin James Fregly, Volume 4. 1973-1977
44 Collected Publications of Melvin James Fregly, Volume 4. 1973-1977
45 Collected Publications of Melvin James Fregly, Volume 4. 1973-1977
45 Collected Publications of Melvin James Fregly, Volume 5. 1978-1982
45 Collected Publications of Melvin James Fregly, Volume 5. 1978-1982
45 Collected Publications of Melvin James Fregly, Volume 5. 1978-1982
45 Collected Publications of Melvin James Fregly, Volume 6. 1983-1987
45 Collected Publications of Melvin James Fregly, Volume 6. 1983-1987
45 Collected Publications of Melvin James Fregly, Volume 6. 1983-1987
45 Collected Publications of Melvin James Fregly, Volume 6. 1983-1987
46 Thermal Physiology by J.R.S. Hales ("Effect of Ethanol on Body Temperature Regulation in the Rat," by Fregly and D.E. Spiers). 1984
46 Thirst: Physiological and Psychological Aspects by Ramsay and Booth ("Effects of Environmental Stresses and Privations on Thirst," by Fregly and N.E. Rowland). 1991
46 Interaction of the Chemical Senses with Nutrition by Kare and Brand ("Preference Threshold for Maltose Solutions in Rats Treated Chronically with the Components of an Oral Contraceptive"). 1986
46 The Chemical Senses and Nutrition by Kare and Maller ("Role of Hormones in the Regulation of Salt Intake in Rats"). 1967
46 Physiology, Environment, and Man by Lee and Minard ("Comments on Cross-Adaptation"). 1970
46 Comparative Mechanisms of Cold Adaptation ("Role of Hormones in the Responses of Homeotherms to Cold"). 1979
46 Thirst: Proceedings of the First International Symposium on Thirst in the Regulation of Body Water by Matthew J. Wayner ("Effect of Hypothyroidism on Water and Sodium Exchange in Rats," by Fregly and R.E. Taylor, Jr.). 1964
46 Peptide Hormone Receptors by Kalimi and Hubbard ("Receptors for Angiotensin II" by Fregly and Collin Sumners). 1987
46 Physiology of Thirst and Sodium Appetite ("Role for A2-Adrenoceptors in Experimentally-Induced Drinking in Rats," by Fregly and N.E. Rowland). 1986
46 Thermal Physiology by J.B. Mercer ("Cold-Induced Hypertension in Rats," by Fregly and Paula Papanek). 1989
46 Temperature Regulation: Recent Physiological and Pharmacological Advances by A.S. Milton ("Tail of the Rat in Temperature Regulation: Effect of Angiotensin II," by Fregly, N.E. Rowland, and J.R. Cade). 1994
46 Fever by James M. Lipton ("On the Central Protein Mediator of Fever," by Fregly, C.C. Barney, M.J. Katovich, P.E. Tyler). 1980
46 Tides of Physiology: Departmental Histories by Arthur B. Otis (Supplement to The Physiologist; includes history of the Physiology Department at UF). 1986
47 Thermoregulation by Clark M. Blatteis ("Effects of Chronic Treatment with Angiotensin II on Thermoregulation in Rats," by Fregly, T. Connor, M.J. Katovich, N.E. Rowland). 1997
47 Proceedings of the Third Midwest Conference on the Thyroid by Bloomfield and Senhauser ("Metabolic Responses to Heat"). 1967
47 NIH Workshop on Nutrition and Hypertension: Proceedings from a Symposium ("Attempts to Estimate Sodium Intake in Humans"). 1985
47 Olfaction and Taste 2: Proceedings of the Second International Symposium by T. Hayashi ("Hormonal Regulation of the Spontaneous Sodium Chloride Appetite of Rats," by Fregly and I.W. Waters). 1967
47 Olfaction and Taste 3: Proceedings of the Third International Symposium by C. Pfaffmann ("Preference Threshold and Appetite for NaCl Solution as Affected by Propylthiouracil and Desoxycorticosterone Acetate in Rats"). 1969
47 History of the American Physiological Society: The First Century, 1887-1987 by Brobeck, Reynolds, and Appel (history of the society, not written by Fregly). 1987
47 The Quarter Century 1925-1950, School of Medicine and Dentistry, University of Rochester (history of the program, not written by Fregly). 1950
47 Neural Integration of Physiological Mechanisms and Behaviour by Mogenson and Calaresu ("Hormonal Interactions in Body Temperature Regulation"). 1975
47 Integrative and Cellular Aspects of Autonomic Functions: Temperature and Osmoregulation (Symposium; includes abstract of Fregly's presentation). 1993
47 Bioenergetics: Proceedings of the International Symposium on Environmental Physiology by R.E. Smith ("Variation of Both Ambient Temperature and Duration of Cold Exposure on Water Intake Following Removal From Cold," by Fregly, Lutherer and Tyler). 1972
47 Sixth International Conference on the Physiology of Food and Fluid Intake: Abstracts (includes abstract for Fregly). 1977
47 International Symposium on Altitude and Cold: Abstracts (includes abstract for Fregly). 1968
47 Annals of Internal Medicine: Nutrition and Blood Pressure Control ("Estimates of Sodium and Potassium Intake"). 1983
47 XXI International Congress of Physiological Sciences (includes abstract for Fregly). 1959
47 Pharmacology of Thermoregulation: Eighth International Symposium (includes abstract for Fregly). 1991
47 Thermoregulatory Mechanisms and Their Therapeutic Implications by Cox et al. ("Temporal Relationship Between the Increase in Metabolic Rate and Tail Skin Temperature Following Administration of Isoproterenol in Rats," by Fregly, Barney, et al.). 1980
47 Annual Review of Nutrition Volume 1 ("Sodium and Potassium"). 1981
47 Environmental Physiology: Aging, Heat and Altitude by Horvath and Yousef ("Thermogenic Drinking in Rats," by Fregly and P.E. Tyler). 1981
48 Collected Papers and Publications of the Department of Physiology, UF Volume 1. 1956-1961
48 Collected Papers and Publications of the Department of Physiology, UF Volume 2. 1962-1966
48 Collected Papers and Publications of the Department of Physiology, UF Volume 3. 1967-1971
48 Collected Papers and Publications of the Department of Physiology, UF Volume 4. 1972-1976
48 Collected Papers and Publications of the Department of Physiology, UF Volume 5 (not bound - in folder). 1977-1980
49 Acclimatization to Cold. Not Dated
49 Action of Angiotensin Converting Enzyme Inhibitors in Rat Brain. Not Dated
49 Activity of the Hypothalamic-Pituitary-Thyroid Axis During Exposure to Cold (1/2). 1983-1988
49 Activity of the Hypothalamic-Pituitary-Thyroid Axis During Exposure to Cold (2/2). 1983-1988
49 Activity of the Hypothalamic-Pituitary-Thyroid Axis During Exposure to Cold. 1989-1990
49 Activity of Hypothyroid Rats in Cold Air. 1960-1961
49 Activity of Hypothyroid Rats in Cold Air. Not Dated
49 Adrenal and Renal Hypertension. 1957
49 Adrenergic Activity of Ortho, Meta, and Para-Octopamine. 1978
49 Adrenergic Effects on Intrapulmonary Airways (Includes Journal Articles). 1978-1984
49 Aldosterone Hypertension in Rats. 1968-1969
49 Aminotriazole on Thyroid Function. Not Dated
49 Aminotriazole, Thyroid Function, and Catecholamines in Nephrogenic Hypertension in Rats. 1968
49 Amphenone B and Hypertension. Not Dated
49 Angiotensin, Aldosterone, and Salt Appetite. 1984
49 Angiotensin, Aldosterone, and Salt Appetite. Not Dated
49 Angiotensin II-Induced Hypothermia. 1984
49 Angiotensin - Induced Thirst. 1976-1978
49 Angiotensin Induced Thirst, Effect and Treatment With Estrogen. 1978-1979
49 Angiotensin Induced Thirst: Peripheral and Control Mechanisms. 1978
49 Angiotensin - Related Induction of Immediate Early Genes in Rat Brain. Not Dated
49 Antidipsogenic Effect of Clonidine on Angiotensin II, Hypertonic Saline, Pilocarpine, and Dehydration-Induced Water Intakes. 1980-1981
49 Antidipsogenic Effect of Clonidine on Angiotensin II, Hypertonic Saline, Pilocarpine, and Dehydration-Induced Water Intakes. 1978-1981
49 Antidipsogenic Effect of Clonidine on Isoproterenol Induced Water Intake. 1980
49 Antihypertensive Activity of Redox Derivatives of Tryptophan. 1990
49 Attempts to Estimate Sodium Intake in Humans. Not Dated
49 Attempts to Estimate Sodium and Potassium Intakes of Man. 1982
49 Attenuation of A B-Adrenergic Response in Rats. 1977
49 Attenuation of Isoproterenol-Stimulated Plasma Renin Activity By Chronic Estrogen Treatment. 1980-1981
49 Attenuation of Pilocarpine Induced Drinking By Chronic Treatment With Estrogens. 1978-1980
49 Augmentation of Isoproterenol-Induced Drinking By Acute Treatment With Certain Dopaminergic Agonists. 1987-1988
49 Augmentation of Isoproterenol-Induced Drinking By Acute Treatment With Certain Dopaminergic Agonists. 1988
49 B-Adrenergic Responsiveness in Cold-Adopted Rats. 1978
49 Brain Angiotensin AT-2 Receptor Antagonism of Water Intake. 1993
49 Behavioral and Physiological Aspects of Body Fluid Homeostasis in Fischer 344 Rats. 1987
49 Beta-Adrenergic Responsiveness in the Rat Following the Acute Administration of Ethanol. 1985
49 Beta-Adrenergic Responsiveness in Desoxycorticosterone-Salt Induced-Hypertension in Rats. Not Dated
49 Beta-Adrenergic Responsiveness of Rats Treated Chronically With Isoproterenol. 1979-1980
49 Beta-Adrenoceptor Subtype Mediating Tail Skin Temperature Response of Rats to Acute Administration of Isoproterenol. 1982
49 Bethanechol-Induced Water Intake in Rats: Possible Mechanisms of Induction. Not Dated
50 Biochemistry of Sodium and Potassium (Book) - Includes Correspondence With Publisher. 1982-1988
50 Biochemistry of Sodium and Potassium (Book) - Includes Correspondence With Publisher. 1982-1988
50 Blood Pressure and Aldosterone. Not Dated
50 Blood Pressure During Exposure to Cold. 1993
50 Bradykinin-Induced Water Intake. 1991-1994
50 Captopril on NaCl Appetite. 1979-1980
50 Captopril on Renal Hypertension. Circa 1979-1980
50 Cardiovascular Responsiveness in Cold Adapted Rats. Not Dated
50 Catecholamine Mediated Diuresis in Turkeys. 1980
50 Catecholamine-Thyroid Hormone Interaction in Cold Acclimated Rats. 1979
50 Catecholamine, Thyroid, and Theophylline in Cold. Not Dated
50 Changes in Beta-Adrenergic Responsiveness in Rats During Chronic Cold Exposure. 1978
50 Changes in Blood Pressure. 1990-1992
50 Changes in Blood Pressure and Dipsogenic Responsiveness to Angiotensin II During Chronic Exposure of Rats to Cold. 1989-1990
50 Changes in the Catecholamines Content of Rat Tissues Following Cold Exposure. Circa 1991
50 Changes in Vascular Responsiveness Following Chronic Exposure to Cold in the Rat. 1983
50 Chronic Dietary Administration of Tryptophan Prevents the Development of DOCA-Salt-Induced Hypertension in Rats. Circa 1986
50 Chronic Treatment With L-5 Hydroxytryptophan Prevents the Development of DOCA-Salt-Induced Hypertension in Rats. 1986-1987
50 Clonidine Antagonism of Angiotensin Related Drinking: A Central Site of Action. 1982-1983
50 Cold Induced Hypertension. 1988-1990
50 Cold Induced Hypertension. Not Dated
50 Cold Induced Hypertension in Rats. 1990-1991
50 Cold Tissue Catecholamines. 1991
50 Comments on Cross Adaptation. 1966-1969
50 Comments on Cross Adaptation. 1968
50 Comments on the Paper "Thyroid-Adrenal Relationship in Altitude Tolerance" By De Bias. Not Dated
50 Comparison of the Hyperhydrating Effects of Angiotensin II and Isoproterenol. 1992
50 Complexing and Depressor Effects of Sulfur Compounds. 1964-1967
50 Control of NaCl Intake By Rats. 1981
50 DDD and Metyrapone in Hypertension. Not Dated
50 DDD on Thyroid and Adrenal Function. Not Dated
50 DOCA on NaCl Appetite. Not Dated
50 DOCA on Natriuretic Substance in Atria. Not Dated
50 DOCA on Preference Threshold For NaCl. Not Dated
50 Dependence of Beta-Adrenergic Responsiveness on Thyroid State of Male Rats. 1980-1983
50 Development of Hypertension in Rats Treated With Aldosterone Acetate. 1968-1969
50 Development of Hypertension in Rats Treated With Aldosterone Acetate. 1963
50 Development of Hypertension in the Dahl Salt-Sensitive Rat: Role of Gonadal Hormones. Not Dated
50 Dietary Intervention and Training in Swimmers. 1991
50 Diminished Metabolic Responsiveness to Beta-Adrenergic Stimulation in Estradiol Benzoate-Treated Rats. 1985-1987
50 Dipsogenesis in Cold-Acclimated Rats. 1980
50 Dipsogenic Effect of L-5 Hydroxytryptophan in Rats. 1980
50 Dipsogenic Responsiveness and Preference Thresholds For NaCl in Long-Evans and Sprague-Dawley Rats. 1989-1991
50 Disruption of Estrous Cycles in Exercise Trained Rats. 1984-1985
51 Dissertation - Acclimatization to Cold Atmospheres (University of Rochester). 1952
51 Diuretics on Renal Iodide Excretion. Not Dated
51 Do Peripheral and Cerebroventricular Injections of Angiotensin II Act at the Same Site? Studies on Additivity of Drinking. 1985-1986
51 Drinking: a Final Common Pathway?. 1983-1984
51 Effect of 3-Amino-1,2,4-Triazole on Hepatic and Renal Deiodination of L-Thyroxine to 3,5,3'-Triiodothyronine. 1980-1981
51 Effect of Acute Administration of an Angiotensin Converting Enzyme Inhibitor, Captopril (SQ14,225) on Experimentally-Induced Thirsts in Rats. 1979
51 Effect of Acute Administration of Bromocriptine on Isoproterenol and Angiotensin II Induced Water Intake in Estrogen Treated Rats. 1986
51 Effect of Acute Administration of Isoproterenol and Angiotensin II, Separately and in Combination on Water Intake and Blood Pressure of Rats. 1981-1983
51 Effect of Ambient Temperature on Beta-Adrenergic Responsiveness in Rats. 1979
51 Effect of Aminotriazole on Some Parameters of Thyroid Function in the Rat. 1967-1968
51 Effect of Amphenone B on Development of Renal Hypertension in Rats. 1962-1963
51 Effect of Angiotensin on Rats. 1988-1992
51 Effect of Angiotensin I Converting Enzyme Inhibitor, MK-421, on Experimentally Induced Drinking. 1982
51 Effect of Antidiuretic Hormone on Sweating and Body Cooling During Intensive Exercise. Not Dated
51 Effect of the Antithyroid Drug Propylthiouracil on the Sodium Balance of Rats. 1962
51 Effect of the Antithyroid Drug Propylthiouracil on the Sodium Balance of Rats. 1962
51 Effect of A Reduction in Sodium Intake on Cold Induced Elevation of Blood Pressure in Rats. 1991-1992
51 Effect of Beta-Andrenergic Antagonists on the Spontaneous Appetite For NaCl Solution in Rats. 1984
51 Effect of Chronic Administration of Deoxycorticosterone Acetate on Salt Appetite of Captopril-Treated Rats. Not Dated
51 Effect of Chronic Administration of Mestranol on Alpha- and Beta-Adrenergic Responsiveness in Female Rats. 1982-1983
51 Effect of Captopril on the Blood Pressure to Angiotensin I in Turkeys. 1980-1981
51 Effect of Chronic Administration of Dexfenfluramine on Blood Pressure. 1992
51 Effect of Chronic Estrogen Treatment on Water Exchange in Rats. 1984
51 Effect of Chronic Dietary Treatment With L-Tryptophan on the Development of Renal Hypertension in Rats. 1986-1987
51 Effect of Chronic Dietary Treatment With L-Tryptophan on the Development of Renal Hypertension in Rats. 1988-1989
51 Effect of Chronic Dietary Treatment With L-Tryptophan on Spontaneous Salt Appetite of Rats. 1983-1988
51 Effect of Chronic Dietary Treatment With L-Tryptophan on the Maintenance of Hypertension in Spontaneously Hypertensive Rats. 1988
51 Effect of Chronic Dietary Treatment With Nicotinic Acid. 1988
51 Effect of Chronic Dietary Treatment With Nicotinic Acid on the Development and Maintenance of Deoxycorticosterone Acetate-Salt-Induced Hypertension. 1987-1988
51 Effect of Chronic Exposure to Cold and Hypoxia. Not Dated
51 Effect of Chronic Exposure to Hypoxia on Blood Pressure and Thyroid Function of Hypertensive Rats. 1963
51 Effect of Chronic Exposure to Hypoxia on Blood Pressure and Thyroid Function of Hypertensive Rats. 1963
51 Effect of Chronic Treatment With Captopril on Reactivity of Aortic Smooth Muscle From Normotensive and Renal Hypertensive Rats. 1982-1983
51 Effect of Chronic Treatment With Clonidine and Spironolacton on Cold-Induced Elevation of Blood Pressure. 1991
51 Effect of Chronic Treatment With Deoxycorticosterone on the Dipsogenic Response to Rats to Isoproterenol and Angiotensin. 1977-1979
51 Effect of Chronic Treatment With Estrogen and Thyroxine, Alone and Combined, on the Rate of Deiodination of L-Thyroxine to 3,5,3'-Triiodothyronine in Vitro. 1985-1986
51 Effect of Chronic Treatment With Thyroxine and Estradiol on Estrogen Concentration in Serum on Hepatic Microsomal Cathechol Estrogen Formation in Female Rats. 1981-1982
51 Effect of Clonidine on the Contractile Responsiveness of Aortic Smooth Muscle to Norepinephrine. 1977-1978
51 Effect of Cycloheximide on Temperature Regulation in Rats. 1979
51 Effect of Dialysis and Diet on Schizophrenia. 1990
51 Effect of Dietary Administration of Enovid For 20 Weeks on Organ to Body Weight Ratio of Certain Organs of Female Rats. 1971-1972
51 Effect of Dietary Treatment With Tryptophan and Nicotinic Acid. 1990
51 Effect of Different Factors of Blood Pressure. Circa 1962
52 Effect of the Dipeptidyl Peptidase Inhibitors, Captopril, Ramipril, and Enalapril, on Water Intake and Sodium Appetite of Sprague-Dawley Rats. Not Dated
52 Effect of Diuretics on Renal Iodide Excretion by Humans. Not Dated
52 Effect of Diuretics on Renal Iodide Excretion by Rats and Dogs (HCZ). 1967
52 Effect of Domperidone on Renal Response to Certain Atrial Natriuretic Substances in Rats. 1989
52 Effect of Exposure to Cold on Evaporative Loss from Rats. 1966-1968
52 Effect of Exposure to Cold on Evaporative Loss from Rats. Not Dated
52 Effect of Hydrochlorothiazide on NaCl Intake. Not Dated
52 Effect of Hypothyroidism on Responsiveness to Beta-Adrenergic Stimulation. 1974-1975
52 Effect of Hypothyroidism on Sodium Chloride Aversion of Renal Hypertensive Rats. 1962
52 Effect of Hypothyroidism on Spontaneous Activity. Circa 1963
52 Effect of Hypothyroidism on Water and Sodium Exchange in Rats (Thirst). 1962-1963
52 Effect of Increased Circulating Angiotensin II (AII) on Fluid Exchange and Binding of AII in the Brain. 1987-1988
52 Effect of Intermittent Exposure to Cold. 1990-1992
52 Effect of Intermittent Exposure to Cold. 1990
52 Effect of Intracerebroventricularly Administered Octopamines and Synephrines on Angiotensin II-Induced Water Intake in Rats. 1984
52 Effect of Intracerebroventricularly Administered Octopamines and Synephrines on Angiotensin II-Induced Water Intake in Rats. 1984
52 Effect of In Vitro Administration of Captopril on Vascular Reactivity of Rat Aorta. 1980-1981
52 Effect of Isomers of DDD on Thyroid and Adrenal Function in Rats. 1967
52 Effect of Isomers of Octopamine on In Vitro Reactivity of Vascular Smooth Muscle Rats. 1978-1980
52 Effect of L-Tryptophan and 5-Hydroxytryptophan on Blood Pressure. 1992
52 Effect of L-Tryptophan on the Blood Pressure of Patients with Mild to Moderate Essential Hypertension. 1989
52 Effect of L-Tyrosine on the Development of Renal Hypertension in Rats. 1984
52 Effect of Long-Term Therapy with Enovid on Some Aspects of Hepatic Lipid Metabolism in Vitro. Not Dated
52 Effect of Losartan Potassium and Deoxycorticosterone Acetate on Tail Skin Temperature Response to Acute Administration of Angiotensin II. 1992
52 Effect of Low Bulk Diet on Water and Electrolyte Exchange in Rats Exposed to Cold. Not Dated
52 Effect of Methylphenidate on Spontaneous Activity, Food Intake, and Cold Tolerance of Propylthiouracil-Treated Rats. 1962-1963
52 Effect of o,p'-DDD (Metyrapone, Renal Hypertension, Thyroid Glands of Rats). 1963-1968
52 Effect of an Oral Contraceptive on Spontaneous Activity of Female Rats. Not Dated
52 Effect of an Oral Contraceptive on Spontaneous Running Activity of Female Rats. 1969
52 Effect of an Oral Contraceptive on Spontaneous Running Activity of Female Rats. 1969-1970
52 Effect of an Oral Contraceptive on Spontaneous Running Activity. Not Dated
52 Effect of an Oral Contraceptive on Spontaneous Running Activity, Salt Appetite and Blood Pressure of Ovariectomized Rats. 1971-1972
52 Effect of Potassium Nitrate Solutions on Blood Pressure of Rats. 1959-1960
52 Effect of Propylthiouracil and Thyroxine on Cooling Rate and Initial Colonic Temperature of Adrenalectomized Rats. 1972-1974
52 Effect of Reduction in Sodium Intake on the Development of Cold-Induced Hypertension in Rats. Circa 1990
52 Effect of Renal Hypertension on Preference Threshold of Rats for Sodium Chloride. 1956
52 Effect of Repeated Exposures to Cold on Flood and Fluid Intakes of Rats. 1991
52 Effect of Reserpine on Body Temperature Regulation of Rat. Not Dated
52 Effect of Saluretic Agents on Blood Pressure and Thyroid Activity of Hypertensive Rats. 1960-1961
52 Effect of Some Substituted Pyrimidines on Development of Deoxycorticosterone-Induced Hypertension in Rats. 1975
53 Effect of Some Substituted Sulfamic Acid Compounds on Development of Renal Hypertension in Rats. 1963-1966
53 Effect of Spironolactone on Spontaneous NaCl Intake of Adrenalectomized Rats. 1966
53 Effect of TDF on the Drinking Response of Rats. 1969-1975
53 Effect of Theophylline on Thyroid Status in the Rat. 1982-1983
53 Effect of Theophylline on Thyroid Status in the Rat. 1982
53 Effect of Thiazides on Metacorticoid Hypertension. Not Dated
53 Effects of Thiazides on Thyroid Glands of Rats. 1965-1966
53 Effect of Thyroxine on Intake and Loss of Sodium by Propylthiouracil-Treated Rats. Circa 1963
53 Effect of Ultracentrifugal Fractions of Rat Renal Homogenates on Uptake and Binding if I131 by Porcine Thyroid Slices In Vitro and Rat Thyroid Gland In Vivo. 1968-1971
53 Effect of Water Temperature During Cold Exposure on Thermogenic Drinking in Rats. 1975-1976
53 Effect of Water Temperature on Post-Cold Exposure Drinking of Rats. 1973
53 Effect of Yohimbine and Tolazoline on Isoproterenol-Induced Water Intake in Rats. 1980-1982
53 Environmental Physiology: Prefatory Remarks. Not Dated
53 Enzyme Induction and o,p'-DDD. Not Dated
53 Estimates of Sodium and Potassium Intakes in Man. Not Dated
53 Estimation of Testosterone Secretion Rate in Rats. 1963-1966
53 Estrogen DOCA Study. 1988-1989
53 Evaluation of Thyroid and Adrenal-Pituitary Function During Cold Acclimation. 1967
53 Factors Affecting Angiotensin II-Induced Hypothermia in Rats. 1984-1985
53 Factors Affecting Indirect Determination of Systolic Blood Pressure of Rats. 1961-1963
53 Factors Affecting Salivary Sodium Concentration, NaCl Intake and Preference and Threshold and Their Interrelationships. Not Dated
53 Factors Affecting Thermogenic Drinking in Rats. 1979
53 Feeding Device for Rats. Circa 1960
53 Fos Induction in Spontaneous Hypertensive Rat Brain. 1994
53 Further Evidence for Reduced Responsiveness to Beta-Adrenergic Stimulation in Renal Hypertensive Rats. 1981-1982
53 Growth Hormone, Somatomedins and Somatostatin. 1961-1964
53 Hormonal Interaction in Body Temperature Regulation. Not Dated
53 Hormonal Interaction in Maintenance of Fluid and Electrolyte Homeostasis in Cold-Exposed Rats. 1989
53 Hormonal Interaction in Thermoregulation. Not Dated
53 Hormonal and Neural Mechanisms of Sodium Appetite. 1985
53 Hormonal Regulation of Salt Appetite. Not Dated
53 Hormonal Regulation of the Spontaneous Sodium Chloride Appetite of Rats. 1964-1967
53 Hormones and Salt Appetite of Rats. Not Dated
53 Hydrochlorothiazide and Salt Appetite in Rats. Not Dated
53 Hyperhydrating Effect of Acute Administration of Angiotensin II in Rats. 1991
53 Hyperhydration in Rats. 1992-1993
53 Hypertension Conference, University of Michigan. 1957
53 Hypertension During Chronic Exposure to Cold. 1989-1991
53 Hypertension in Adrenalectomized Rats. 1959
54 Hypothyroidism and Heat Tolerance. Not Dated
54 Increased Responsiveness of Heart Rate to Beta-Adrenergic Stimulation in Cold Adapted Rats. 1976
54 Increased Water Exchange in Hypothyroid Rats. 1960
54 Induction of an Appetite for Sodium in Rats Which Show No Spontaneous Preference for NaCl Solution - Fischer 344 Strain. 1986-1987
54 Influence of Thyroactive Iodinated Casein on Beta-Aminopropionitrile-Induced Aortic Ruptures of Turkeys. Circa 1977
54 Inhibition of Sodium Transport in Frog Skin and Iodination of Tyrosine (Symposium, Munster, Germany). 1984-1985
54 Inhibition of Thermogenic Drinking by Beta-Adrenergic Antagonists. Not Dated
54 Interaction of Adrenal and Thyroid Gland. 1960
54 Interaction of Pregnancy and Hypertension. Not Dated
54 International Conference on Implementing Dietary Guidelines. 1980-1981
54 Interrelationship Among Kidney Weight, Blood Pressure and the Thyroid Gland. 1968
54 Intragastric and Intraperitoneal Loads on Water Intake. 1986
54 In-Vivo Catecholamine Formation from Phenylephrine. 1982
54 Isoproterenol Drink in Estrogen-Treated Rats. 1977
54 Isoproterenol in Estrogen-Treated Rats. 1974-1976
54 L-5-Hydroxytryptophan in the Rat. 1980-1981
54 Lactoperoxidase-Catalyzed Iodination of L-Tyrosine to Assess Antithyroid Activity of a Factor Present in Certain Tissues of Mammals. 1980
54 Localization of Changes in Immediate Early Gene in Brain (Angiotensin II). Not Dated
54 Losartan Potassium and Deoxycorticosterone Acetate on Tail Skin Temperature. 1992
54 Maltose Preference Threshold and Estrogen. 1985-1986
54 Marathon Running: Physiological and Chemical Changes. 1989
54 Mediation of Isoproterenol-Induced Thirst in Rats by Beta2-Adrenergic Receptors. 1977-1978
54 Metabolic Adaptations to Temperature and Altitude. 1965
54 Metabolic Responses to Heat. Not Dated
54 Metabolic Responses to Heat (Midwest Conference on the Thyroid). 1967
54 Metabolic Responsiveness of Spontaneously Hypertensive (SH) Rats to Isoproterenol. Not Dated
54 Methylphenidate on Spontaneous Activity. Not Dated
54 Mineralocorticoids on AII Receptors. 1985-1986
54 Mineralocorticoids on NaCl Appetite. 1965-1966
54 Modeling Thirst. 1981-1982
54 Modification of Thyroid Function During Development of Experimental Renal Hypertension in Rats. Not Dated
54 Modulation of Angiotensin II Binding Sites in Neuronal Cultures. 1988
54 Modulation of Angiotensin II Binding Sites in Neuronal Cultures by Mineralocorticoids. 1988
54 M-Octopamine: Normal Occurrence with Rho-Octopamine in Mammalian Sympathetic Nerves. 1984
54 NaCl Aversion of Hypertensive Rats. 1958-1959
54 NaCl Intake and Preference Threshold of Spontaneously Hypertensive Rats. 1970-1975
54 Natriuretic Activity of Sydnones. 1964
54 Normal Excretion of M-Hydroxymandelic Acid in Hypertensive Patients. 1979-1980
54 Nycthemeral Rhythms and Sodium Chloride Appetite in Rats. Circa 1983
54 On the Central Protein Mediator of Fever. 1979-1980
55 On the Mechanism of Serotonin-Induced Dipsogenesis in the Rat. 1982-1983
55 On the Spontaneous Intake of NaCl Solutions by Dogs. Not Dated
55 Oral Contraceptives and High Blood Pressure. 1977-1981
55 Oral Contraceptives and High Blood Pressure: A Review. 1976-1977
55 Oral Contraceptives-Induced Hypertension in Rats (Progress Report draft). Not Dated
55 Oral Contraceptives on Blood Pressure of Spontaneously Hypertensive Rats. Not Dated
55 Oral Contraceptives on Salt Appetite, Running Activity and Blood Pressure. Not Dated
55 Oral Contraceptives and Water Temperature on Post-Cold Drinking, Thermogenic Drinking in Rats, etc. Circa 1974
55 Osmoreceptor Mediation of Thirst. 1981
55 Peptide Hormone Receptors. 1985-1987
55 Peripheral Body Temperature and Thermogenic Drinking in Cold Treated Rats. 1975
55 Peru - Machu Picchu. Not Dated
55 Physiologic Response to Chronic Dietary Tyrosine Supplementation in DOCA Salt Treated Rats. Not Dated
55 Physiological Regulations in Adaptation. Not Dated
55 Physiological Responses Due to Exposure to Low Temperatures. Circa 1986
55 Plasma Osmolality and Flow Resistance. Not Dated
55 Post-Cold Drinking Phenomenon in Rats. 1964-1968
55 Post-Cold Drinking Response. Not Dated
55 Post-Cold Exposure Drinking (Na Deficient Diet). Not Dated
55 Post-Hypoxic Drinking. Not Dated
55 Postingestinal Factors and AII Drinking. 1986
55 Potassium Nitrate and Blood Pressure. Not Dated
55 Potassium Supplementation and Performance. Circa 1958
55 Prazosin and L-Arginine on Cold-Induced Hypertension. 1992-1994
55 Preference Threshold for NaCl Solutions and Sodium Homeostasis in Hypophysectomized Rats. 1989
55 Preference Threshold for NaCl Solutions and Sodium Homeostasis in Hypophysectomized Rats. 1988-1989
55 Prevention of Cold-Induced Increase in Blood Pressure of Rats by Captopril. 1991
55 Prevention of Deoxycorticosterone Induced Hypertension by Dietary Tryptophan and Calcium. Not Dated
55 Prevention of DOCA Induced Hypertension in Rats by Chronic Treatment with Tryptophan. 1986
55 Proposed Mechanism for the Increased 5'-Monodeiodination of Thyroxine in Cold-Acclimated Rats. 1981
55 Propylthiouracil and Hypertension. Not Dated
55 PTU and Hypertension. Circa 1958
55 PTU and Salt Preference. Not Dated
55 PTU and Sodium Balance. Not Dated
55 PTU on Aldosterone Secretion. Not Dated
55 PTU on Intake and Loss of Sodium. Not Dated
55 Radioactive Iodine Treatment of Hypertension. Not Dated
55 Receptor Modulation and Biological Responses In Vivo and in Intact Cells In Vitro. Circa 1986
55 Reduced Dipsogenic Responsiveness to Intracerebroventricularly Administered Angiotensin II in Estrogen-Treated Rats. 1984-1985
55 Reduced Responsiveness to Beta-Adrenergic Stimulation in Renal Hypertensive Rats. 1978
55 Re-Examination of the Effect of Either a Lateral or Third Ventricular Cannula on Captopril-Induced Salt Appetite in Rats. 1987
55 Regulation of Intakes of Water and NaCl Solutions in Fischer 344 Rats. 1988
55 Regulation of Intakes of Water and NaCl Solutions in Fischer 344 Rats. Not Dated
55 Regulation of Sodium Chloride Intake. Not Dated
55 Regulation of Sodium Chloride Intake by Normotensive and Hypertensive Rats. 1961
55 Regulation of Sodium Chloride Intake by Rats. 1963-1964
56 Relationship Between Drinking and Increase in Tail Skin Temperature of Rats Treated with L-5-Hydroxytryptophan. 1995
56 Relationship Between Thermogenic Drinking and Plasma Renin Activity in the Rat. 1979
56 Renal Denervation on Cold-Induced Hypertension. 1994-1995
56 Renal Peptide Inhibiting Sodium Transport Across Frog Skin. 1984-1985
56 Renal Response of Cold Exposed Rats. 1972
56 Renal Thyroid Interrelationship in Hypertension. 1966-1982
56 Renal Thyroid Interrelationship in Normotensive and Hypertensive Rats. 1981
56 Renal Thyroid Interrelationships. Not Dated
56 Repletion of Acute Sodium Deficit in Rats Drinking Sodium Chloride Solution. 1992
56 Requirement of Castrated Male Rats for Testosterone Propionate. Not Dated
56 Research Ideas - Oral Contraceptives. 1972-1984
56 Response to Thermal Stress in the Rat Following Acute Administration of Ethanol. 1982-1983
56 Reversal by Theophylline of Some Changes Characteristically Accompanying Hypothyroidism in Rats. 1969-1971
56 Reversibility of Cold-Induced Hypertension. 1989
56 Reviews. 1969-1970
56 Reviews. 1970-1971
56 Reviews. 1971-1972
56 Reviews. 1972-1973
56 Reviews. 1973-1974
56 Reviews. 1974-1975
56 Reviews. 1975-1976
56 Reviews. 1976-1977
56 Reviews. 1981
56 Role of Angiotensin II Receptors in Tail Skin Temperature Response to Isoproterenol. 1992-1993
56 Role of Chance in Discovery. 1978-1979
56 Role of Chance in Discovery. Not Dated
56 Role of Hormones in the Response of Homeotherms to Cold. 1977-1979
57 Role of Salt in Cardiovascular Hypertension. 1981
57 Role of Salt in Hypertension. 1978
57 Role of the Thyroid Gland in Hypertension. Circa 1960
57 Role of the Thyroid Gland in the Metabolic Responses of Mammals to Heat. Not Dated
57 Saline Ingestion, Captopril, Alpha-Adrenergic Responsiveness. 1986-1990
57 Salivary Na - Concentration and NaCl Intake. Not Dated
57 Salt Appetite. Not Dated
57 Salt Appetite of Adrenalectomized Rats. Circa 1958
57 Salt Appetite of Goitrogen-Treated Rats. Not Dated
57 Salt Appetite of Hypothyroid Rats. Circa 1961
57 Salt Intake by Man. Circa 1981-1982
57 Saluretics in Hypertension. 1959-1963
57 Secretion of Aldosterone by Adrenal Glands of Propylthiouracil-Treated Rats. 1964-1965
57 Sensitization of Sodium Appetite. Not Dated
57 Serotonin and Drinking. 1986-1987
57 Serum Sodium Concentration of Hypertensive Rats: Relation to NaCl Intake, Blood Pressure and Age. 1955
57 Sodium and Potassium Exchanges in Adrenalectomized Rats. 1969-1970
57 Sodium and Potassium Intakes of Man. Circa 1976-1988
57 Sodium Appetite in Rats. 1988-1989
57 Sodium Appetite: Species and Strain Differences. 1988
57 Sodium Loss of PTU-Treated Rats. Not Dated
57 Some Beta Responses to Administration of Isoproterenol to Turkeys. 1975-1977
57 Some Characteristics of Post-Hypoxia-Induced Drinking in Rats. 1990
57 Spironolactone on Salt Intake. Not Dated
57 Spontaneous NaCl Appetite Induced by Administration of an Oral Contraceptive and Its Components to Rats. 1979-1980
57 Strain Differences in Preference Threshold for NaCl. 1991
57 Studies on the Isolation of a Thyroid Depressing Factor of Renal Origin in the Rat. 1968-1971
57 Substituted Pyrimidines and Hypertension. Not Dated
57 SU-4885 (Metyrapone) and NaCl Intake. 1966-1968
57 Symposium on Oral Contraceptives and High Blood Pressure. 1973
57 Tail of the Rat in Temperature Regulation (Angiotensin II). Not Dated
57 Temporal Relationship Between the Increase in Metabolic Rate and Tail Skin Temperature Following Administration of Isoproterenol to Rats. 1978-1979
57 Thermogenic Drinking: Mediation by Osmoreceptors and Angiotensin II Receptors. 1981-1982
57 Thermogenic Drinking in Rats. 1979-1981
57 Thesis: Evidence of a Time Correlation Between First Movement and Striations in the Skeletal Muscle of the Frog. 1949
57 Thirst Immediately Following Removal of Rats from Graded Levels of Hypoxia. 1970-1971
57 Thirst Immediately Following Removal of Rats from Graded Levels of Hypoxia. Not Dated
57 Thirst and Sodium Appetite in Mice. 1986-1987
58 Thyroid Activity of Hypertensive Rats. Not Dated
58 Thyroid Activity of Spontaneous Hypertensive Rats (1). 1974-1975
58 Thyroid Activity of Spontaneous Hypertensive Rats (2). 1974
58 Thyroid and Adrenal-Pituitary Function During Cold Acclimation. Not Dated
58 Thyroid and Antithyroid Activities, Thyroid Depressing Factor of Renal Origin. Not Dated
58 Thyroid and Hypertension. 1960
58 Thyroid and Metabolic Responses to Heat. 1966-1968
58 Thyroid and Metabolic Responses to Heat. Not Dated
58 Thyroid Gland and Experimental Hypertension. 1966-1967
58 Thyroid Gland and Renal Hypertension. 1956-1967
58 Thyroidectomy, Adrenalectomy and Cold Exposure. 1960
58 Thyroidectomy and Hypertension. Not Dated
58 Thyroxine and Isoproterenol on B-Adrenoreceptors. Not Dated
58 Tolerance of Estrogen-Treated Rats to Acute Cold Exposure. 1977-1979
58 Use of An Iodide-Specific Electrode to Study the Lactoperoxidase-Catalyzed Tyrosine. 1979
58 Water and Electrolyte Exchange During Exposure to Cold. 1965-1981
58 Water and Electrolyte Exchange During Exposure to Cold. 1970
58 Water and Electrolyte Exchange During Exposure to Cold. 1971
58 Water and Electrolyte Exchange During Exposure to Cold. 1975-1981
58 Water and Electrolyte Exchange During Exposure to Cold. 1991
58 Water and Electrolyte Exchange During Exposure to Cold. 1980-1982
58 Water and Na in Hypothyroidism. Not Dated
58 Water and NaCl Solution Intake. 1967
58 Water Deprivation-Induced Drinking in Rats: The Role of Angiotensin II. 1981-1982
58 Water Exchange in Hypothyroidism. 1961
58 Water Exchange in Rats Exposed to Cold, Hypoxia and Both Combined. 1976
58 Water Intake of Rats Immediately After Exposure to a Cold Environment. 1966
58 Water vs. NaCl Intake by Rats. 1985-1986
58 Xanthines on Responsiveness to Isoproterenol. Not Dated


Writings by Others 1932-1991

Fregly maintained numerous reference files of articles, reprints, and papers created by other authors who worked in related research areas. The series begins with his "alphabetical by author" files and then includes all other files arranged alphabetically according to subject or author. Prominent topics include hypertension, body temperature, cold and altitude, salt, and oral contraceptives. In addition to the alphabetical by author files, there are also files for writings by E.F. Adolph and Mark Evered. Numerous files include notes made by Fregly about the writings, as well as a small amount of correspondence with various authors.


Box
59 Alphabetical by Author - A. Not Dated
59 Alphabetical by Author - B. Not Dated
59 Alphabetical by Author - B. Not Dated
59 Alphabetical by Author - B. Not Dated
59 Alphabetical by Author - C. Not Dated
59 Alphabetical by Author - D. Not Dated
59 Alphabetical by Author - D. Not Dated
59 Alphabetical by Author - E. Not Dated
59 Alphabetical by Author - F. Not Dated
59 Alphabetical by Author - G. Not Dated
59 Alphabetical by Author - H-I. Not Dated
59 Alphabetical by Author - H-I. Not Dated
59 Alphabetical by Author - J. Not Dated
59 Alphabetical by Author - K. Not Dated
59 Alphabetical by Author - L. Not Dated
59 Alphabetical by Author - M. Not Dated
59 Alphabetical by Author - M. Not Dated
59 Alphabetical by Author - N-O. Not Dated
59 Alphabetical by Author - P-Q. Not Dated
59 Alphabetical by Author - R. Not Dated
59 Alphabetical by Author - S. Not Dated
60 Alphabetical by Author - S. Not Dated
60 Alphabetical by Author - T. Not Dated
60 Alphabetical by Author - U-V. Not Dated
60 Alphabetical by Author - W. Not Dated
60 Alphabetical by Author - X-Y-Z. Not Dated
60 Adolph, E.F. 1939-1980
60 Adrenal Cortex. 1959-1979
60 Adrenal Cortex. 1963-1981
60 Adrenal Medula. 1951-1975
60 Altitude Adaptation Mechanisms. 1950-1963
60 Altitude Adaptation Mechanisms. 1951-1983
60 Body Processes During Exercise. 1971-1972
60 Body Temperature Regulation (Acclimatization - Cold). 1948-1981
60 Body Temperature Regulation (Acclimatization - Cold). 1950-1979
60 Body Temperature Regulation (Acclimatization - Cold). 1949-1972
60 Body Temperature Regulation (General Characteristics). 1939-1975
60 Body Temperature Regulation (General Characteristics). 1935-1970
60 Body Temperature Regulation (Physiological Responses to Cooling). 1953-1982
60 Body Temperature Regulation (Physiological Responses to Cooling - Endocrine). 1933-1982
61 Body Temperature Regulation (Physiological Responses to Cooling - Endocrine). 1958-1982
61 Body Temperature Regulation (Physiological Responses to Cold - Pharmacological Effects). 1948-1978
61 Cold and Altitude Experiments. 1942-1978
61 Cold and Altitude Experiments. 1944-1970
61 Cold Exposure (Metabolic Rate and Thyroidectomy). 1950-1981
61 Cold Exposure on Thyroid Activity. 1951-1983
61 Dehydration Drink - Effect of Beta Blockade. 1947-1989
61 Dietary Sodium and Potassium (1). 1973-1984
61 Dietary Sodium and Potassium (2). 1979-1985
61 Dietary Sodium and Potassium (3). 1973-1985
61 Evered, Mark. 1987-1991
61 Fluid Replacement During Exercise and After Thermal Dehydration. Not Dated
61 Fragmentation Pyrolysis. 1966
61 Genetic Analysis of Salt Appetite and Blood Pressure. Not Dated
61 Hypertension - Brain Catechols. 1961-1983
61 Hypertension - Brain Catechols. 1970-1985
61 Hypertension - Brain Catechols. 1969-1981
61 Hypertension - Regulation of Sodium Exchange. 1944-1980
61 Hypoxia. 1953-1970
61 Hypoxia. 1949-1982
61 Hypoxia. 1949-1967
61 Hypoxia. 1949-1966
62 Hypoxia. 1947-1968
62 Oral Contraceptive - Hypertension. 1973-1982
62 Oral Contraceptive - Induced Hypertension. 1959-1980
62 Oral Contraceptive - Induced Hypertension in Rats. 1935-1981
62 Oral Contraceptive - Induced Hypertension in Rats. 1935-1981
62 Oral Contraceptives. 1959-1981
62 Renal Hypertension. 1967-1969
62 Respiratory System. 1954-1970
62 Salt Appetite. 1959-1967
62 Salt Appetite. 1960-1983
62 Salt Appetite. 1944-1970
62 Salt Appetite. 1952-1983
62 Salt Taste - Hypertension. 1934-1985
62 Sodium and Hypertension. 1949-1981
62 Sodium and Hypertension. 1972-1980
62 Sodium and Hypertension. 1949-1980
62 Thirst and Drinking. 1932-1981
62 Thyroid - Miscellaneous. 1949-1983


Teaching Materials and University of Florida Files 1949-1994

This series includes lecture notes, examinations, laboratory exercises, course materials, and correspondence related to Fregly's tenure as an educator and researcher at Harvard Medical School and the University of Florida College of Medicine. The majority of the files date from his years at UF in the Department of Physiology beginning in 1956. The correspondence files include letters and memoranda between Fregly and colleagues such as Allen Neims, Neil Rowland, Ian Phillips, and Emanuel Suter. Topics include teaching assignments, administration of the department and college, laboratory space and equipment, and academic curriculum. The series also includes histories of the College of Medicine and Department of Physiology.


Box
63 Appointment Papers, Salary Information. 1957-1994
63 Candidate for Chairmanship of Department of Physiology. 1967-1978
63 Correspondence with Emanuel Suter (Dean, UF). 1966-1968
63 Courses - BMS 6576 - Body Temperature Regulation. 1986
63 Courses - Endocrinology and Metabolism. 1972
63 Courses - Laboratory Exercises in Physiology. 1968
63 Courses - MED 520 - Laboratory Exercises in Physiology. 1963
63 Courses - MED 520 - Laboratory Exercises in Physiology. 1963-1964
63 Courses - MED 520 - Laboratory Exercises in Physiology. 1965
63 Courses - MED 520 - Laboratory Exercises in Physiology. 1965
63 Courses - MED 520 - Laboratory Exercises in Physiology. 1966
63 Courses - MED 520 - Laboratory Exercises in Physiology. 1967
63 Courses - MED 521 - Laboratory Exercises in Physiology. 1964
63 Courses - MED 522 - Laboratory Manual. 1958
63 Courses - MED 625 - Body Temperature Regulation. Not Dated
63 Courses - MED 625 - Body Temperature Regulation (1). 1958-1973
63 Courses - MED 625 - Body Temperature Regulation (2). 1958-1973
63 Courses - MED 625 - Body Temperature Regulation (3). 1958-1973
63 Courses - MED 625 - Body Temperature Regulation. 1958
63 Courses - MED 625 - Body Temperature Regulation. 1973
63 Courses - MED 625 - Body Temperature Regulation. 1973
63 Courses - MED 625 - Body Temperature Regulation. 1973
63 Courses - MED 626 - Recent Advances in Physiology (Thyroid Seminar). Circa 1964
64 Courses - MED 638 - Physiology of the Mammalian Thyroid Gland. 1972
64 Courses - MED 638 - Physiology of the Mammalian Thyroid Gland. 1974
64 Courses - MED 638 - Physiology of the Mammalian Thyroid Gland. 1976
64 Courses - Physiology 200. 1949-1950
64 Courses - Statistics 651 (Design of Experiments). 1963-1964
64 Department Memos. 1987
64 Departmental Evaluation of Performance. 1961-1984
64 Examinations. 1952-1971, Not Dated
64 Examinations. 1953-1965
64 Examinations. 1957-1967
64 Examinations. 1963-1972, Not Dated
64 Examinations. 1963-1975
64 Examinations. 1963-1979
64 Examinations. 1963-1979
64 Examinations. 1964-1977
64 Examinations and Laboratory Exercises. 1966-1967, Not Dated
64 Examinations and Laboratory Exercises. 1966-1967, Not Dated
64 General Correspondence (Members of the Department of Physiology). 1965-1974
64 Harvard Medical School Laboratory Manual. 1952-1953
65 Harvard Medical School Laboratory Manual. 1956
65 High School Student Science Training Program. 1987
65 History of the UF College of Medicine and Department of Physiology ("The Way It Was"). Not Dated
65 Inspection of School Curriculum. 1965
65 Laboratory Equipment (Manuals). 1987-1988
65 Laboratory Exercises. 1964-1966, Not Dated
65 Lecture Notes - Adrenal Cortex. 1972-1976
65 Lecture Notes - Adrenal Cortex. Circa 1978
65 Lecture Notes - Appetite and Hunger. Circa 1974
65 Lecture Notes - Blood Volume. Not Dated
65 Lecture Notes - Capillaries. Not Dated
65 Lecture Notes - Comparative Physiology of Thyroid Gland. Not Dated
65 Lecture Notes - Digestion and Secretion. Not Dated
65 Lecture Notes - Endocrine Control Mechanisms. 1972-1977
65 Lecture Notes - Estimates of Na and K Intakes by Man. 1976-1988
65 Lecture Notes - Female Sex Hormones. 1972-1979
65 Lecture Notes - Female Sex Hormones. Circa 1967
65 Lecture Notes - Homeostasis. Not Dated
65 Lecture Notes - Homeostasis. 1961-1972
65 Lecture Notes - Hypertension. Not Dated
65 Lecture Notes - Hypothalamus Pituitary Adrenal Interrelationships. 1974
65 Lecture Notes - Introductory Lecture Notes (Physiology). 1971
65 Lecture Notes - Male Sex Hormones. Not Dated
65 Lecture Notes - Mechanism of Thyroid Secretion. 1959
65 Lecture Notes - Motility of Gastro-Intestinal Track. Not Dated
65 Lecture Notes - Nerve - Muscle Exercise. 1953-1954
66 Lecture Notes - Pancreas and Diabetes. 1975-1978
66 Lecture Notes - Parathyroid Gland. 1975
66 Lecture Notes - Regulation of Blood Pressure. 1958-1962
66 Lecture Notes - Renal Hypertension. 1970-1976
66 Lecture Notes - Renal Physiology. 1955-1956
66 Lecture Notes - Role of Thyroid Gland in Water and Sodium Mineral Metabolism. Not Dated
66 Lecture Notes - Sodium. 1964
66 Lecture Notes - Stomach, Pancreas, Bile and Small Intestine. 1954
66 Lecture Notes - Temperature Regulation. 1954-1963
66 Lecture Notes - Thirst. 1965-1977
66 Lecture Notes - Thyroid Glands. 1978-1986
66 Lecture Notes - Thyroid-Glucocorticoid Interaction. Circa 1965-1966
66 Neims, Allen (Dean, College of Medicine) and Phillips, Ian (Chair, Department of Physiology). 1981-1994
66 Neims, Allen - Regarding Laboratories in the Nuclear Sciences Building. 1994
66 Nomination of J. Lee Dockery as Dean of College of Medicine. 1988
66 Nuclear Sciences Building Space. 1980-1981
66 Office Calendars. 1987-1991
66 Purchase of a Scintillation Counter. 1979
66 Rowland, Neil. 1985-1993
66 Seminar - Application of Basic Sciences to Clinical Practice. 1962


Speeches and Seminars 1933-1994

Includes materials used by Fregly to prepare for and present various talks and seminars. In addition to speeches and drafts of speeches, several folders also include notes and correspondence pertaining to the speech or presentation. Several files are related to talks given at symposia and conferences, and one folder includes materials used in a Federation of American Societies for Experimental Biology (FASEB) poster session.


Box
67 Adaptations of Rats to Cold (Seminar). Not Dated
67 An Unusual Vasodilatory Response to Angiotensin II. 1992-1994
67 Angiotensin Study (Seminar). 1977-1986
67 Anti-Thyroid Compounds on Water and Sodium Exchange (Seminar). Not Dated
67 Atrial Natriuretic Factor (Research Seminar). 1985
67 Cross-Adaptations and Their Significance. Not Dated
67 Declaration of Sodium Content of Foods. 1982
67 Edward F. Adolph Memorial. 1987
67 Estrogen and the Kidney. 1984
67 Factors Affecting AII-Induced Appetite. 1986-1987
67 FASEB Poster Session (Angiotensin II Cold Adaptation). 1988
67 FASEB Poster Session (Chronic Cold Exposure on Adrenergic Function). 1987
67 Fluid Exchanges During Chronic Exposure to Simulated Attitude (Seminar). 1967
67 Induction of Hypertension in Rats (Bad Nauheim, Germany). Not Dated
67 International Symposium on Pharmacology of Thermoregulation (Giessen, Germany). 1994
67 Interview on Blood Pressure. Not Dated
67 Introduction of Dr. Bengt Saltin (Speech about Dr. Edward F. Adolph). 1994
67 Oral Contraceptives and Hypertension (Seminar). Not Dated
67 Oral Contraceptives (Seminar). 1976-1978
67 Oral Contraceptives Symposium. 1973
67 Pharmacological Aspects of Clonidine. 1977
67 Salt Appetite (Rats) (Seminar). 1977-1978
67 Scientific Meetings - Talks, Seminars. 1949-1961
67 Symposium - Role of Salt in Cardiovascular Hypertension. 1961
67 Talks and Seminars. 1966-1982
67 Talks and Seminars. 1966-1987
67 Thermal Physiology Symposium (Aberdeen, Scotland). 1933
67 Thirst Symposium [FSU] (Seminar). 1963
67 Thyroid and Hypertension (Seminar). 1974
67 Tolerance of Estrogen-Treated Rats (Seminar). 1977
67 Tryptophan and Hypertension (Seminar). 1987-1994
67 Vasodilatory Response to Angiotensin (IUPS Congress - Glasgow). 1993
67 Water Balance of Animals Exposed to Hypoxia (Seminar). 1966


Photographs 1944-1994

Primarily consists of graphs and tables used in publications and presentations to convey research results. Other subjects include E.F. Adolph, G.W. Lighty, Jr., laboratory rats, experiments in progress, and laboratory equipment. Although the majority of the images are photographic prints, there are also dozens of slides and a small number of negatives.


Box
68 Activity of Hypothyroid Rats in Cold Air. 1960-1961
68 Activity of Hypothyroid Rats in Cold Air. Not Dated
68 Adrex Diuresis Experiments (1). 1965
68 Adrex Diuresis Experiments (3). 1968-1969
68 Adex-Salt Hypertension - Experiment 2. 1958
68 Adolph, Edward F. (Introduction of Dr. Bengt Saltin - Speech About Dr. Adolph). 1994
68 Adrenal and Renal Hypertension. 1957
68 Adrenal and Renal Hypertension. Not Dated
68 Alcohol Diuresis. 1965-1966
68 Aldosterone (Graphs and Microscopic Views of Rats). Circa 1957-1959
68 Aldosterone Hypertension in Rats. Circa 1968
68 Aldosterone Secretion and NaCl Intake. 1963-1967
68 Amino Acids and TDF Analysis. 1984-1986
68 Aminotriazole on Thyroid Function. Not Dated
68 AngII Drink - Bromocriptine and Dopamine. 1980-1984
68 Angiotensin, Aldosterone and Salt Appetite. 1984
68 Angiotensin-Induced Drinking (Spiperone, Atropine). 1984-1988
68 Angiotensin-Induced Thirst - Effect of Treatment with Estrogen. 1978-1979
68 Angiotensin-Induced Thirst - Peripheral and Central Mechanisms. 1978
68 Atenolol on Isoproterenol Drink. 1980
68 Attenuation of a Beta-Adrenergic Response in Rats. 1977
68 B-Adrenergic Responsiveness in Cold-Adapted Rats. 1978
68 Biochemistry of Sodium and Potassium. 1982-1988
68 Blood Pressure and Aldosterone. Not Dated
68 Blood Pressure During Exposure to Cold. 1993
68 Blood Pressure Measurement. 1959-1961
68 Bromocriptine on Induced Drinking. 1984-1988
68 Captopril on NaCl Appetite. 1978-1979
68 Captopril - Renal Hypertension. 1979
68 Carbethoxy-2-Thiouracil. 1966
68 Clonidine - Tail Skin Temperature and Heart Rate in Response to Isoproterenol. 1979-1982
68 Cold and Altitude Experiments (Sodium and Potassium). 1973
68 Cold and Altitude - Experiment 5. 1970-1973
68 Cold and Altitude Experiments. 1969-1974
68 Cold and Altitude Experiments (Plasma and Urinary Osmolarity). 1972
68 Cold Blood Pressure Study. 1981-1985
68 Cold - Decrease in Isoproterenol Sensitivity - TST. 1976
68 Cold - Effect of Low Bulk Diet on Water and Electrolyte. 1967-1970
68 Cold Experiment 31. 1991
68 Cold Exposure. 1973-1974
68 Cold-Induced Hypertension. 1988-1990
68 Cold Rats - Organ Weight and Blood Pressure. 1977
68 Cold - Water and Electrolytes During Cold. 1965-1975
68 Contractile Substance in Plasma and Urine of Rats. 1986
68 Cooling Tests on Normal and Adx Rats. 1958
68 DA2 - Agonist and Drinking. 1984-1985
68 DDD and Metyrapone in Hypertension. Not Dated
68 Direct Blood Pressure Experiments. 1962-1965
68 Diuresis Experiments (Water, Urea, KCl and Pitressin Diuresis). 1965
68 Diuretics on Iodine Excretion. Not Dated
68 Diuretics on Renal Iodine Excretion. Not Dated
68 DOCA - Adrex Salt Taste Threshold. Circa 1969
68 DOCA and NaCl Appetite. Not Dated
68 DOCA on Preference Threshold for NaCl. 1967
68 DOCA on Preference Threshold for NaCl. Not Dated
68 Effect of Administration of Norethynodrel and Ethynyl Estradiol on Intake and Excretion of Female Rats. 1974-1975
68 Effect of Aminotriazole on Thyroxine I131. 1967
68 Effects of Chlorothiazide and Hydrochlorothiazide on Thyroid. 1958-1965
68 Effects of Clonidine on Responses to Graded Doses of Pitressin. 1977-1979
68 Effect of Cold on Urinary Concentrating Ability of White Rats. 1965-1967
68 Effect of Different Factors on Blood Pressure. Circa 1962
68 Effect of Estradiol in Rats. 1983-1984
68 Effect of Heat Exposure on Fluid Exchange. Not Dated
68 Hormonal and Neural Mechanisms of Sodium Appetite. Not Dated
68 Hormonal Regulation of Salt Appetite. Not Dated
68 Effects of Hypothyroidism on Spontaneous Activity. Circa 1963
68 Effects of Indomethacin on Warm-Adapted Rats. 1976-1985
68 Effect of Isoproterenol on Oxygen Consumption and Temperature of Rats. 1977-1981
68 Effect of Isoproterenol on Rate of Oxygen Consumption and Temperature of Rats. 1977
68 Effect of TDF on Frog Skin. 1983-1985
68 Field - DDD and Ethionine. 1966
68 Effects of Isoproterenol, Saline and Bradykinin in S2 14225 and Captopril-Treated Rats - 2. 1978-1979
68 Effects of Isoproterenol, Saline and Bradykinin in S2 14225 and Captopril-Treated Rats - 1. 1978
68 Effect of Maltose on NaCl Preference Threshold of Rats. 1968
68 Effect of an Oral Contraceptive on Spontaneous Running Activity. Not Dated
68 Effects of Reserpine on Body Temperature of Rats. Not Dated
68 Effect of Theophylline on Thyroid Status in the Rat. 1982-1983
68 Effects of Thiazides on Metacorticoid Hypertension. Not Dated
68 Effects of Varying Conclusion of Resorcinol. 1973-1974
68 Enovid Female Rats - Salt Specificity Experiments. 1972
68 Experiments in Progress. 1963-1968
68 Feeding Device for Rats. 1960
68 Feeding Device for Rats. Circa 1960
68 Graphs from Various Experiments. Not Dated
68 HCZ - Effect on NaCl Intake. 1961-1967
68 Heat Production - Heat Loss Experiments on Maltose Rats. Not Dated
68 Histological Effects of Tapazole. Not Dated
68 Hyperhydration - A-II and NaCl Load. 1992
68 Hyperhydrating Effects of Angiotensin II. 1991
68 Hypertension in Adrenalectomized Rats. 1959
68 Hypertension in Adrenalectomized Rats. Circa 1960
68 Hypertension - Regulation of Na Exchange. 1944-1980
68 Hypertension - Thyroxine I131 Study 3. 1967
68 Hypothyroidism and Heat Tolerance. Not Dated
68 Hypothyroidism on Maintenance of Body Temperature. 1957
68 Hypox Rats. 1985-1988
68 Indomethacin Drink Experiment on Isoproterenol Drink. 1977-1980
68 Intake Study for Thyroxin Threshold. 1971-1973
68 Interaction of Adrenal and Thyroid Glands. 1960
68 Interaction of Adrenal and Thyroid Glands. 1960
68 Intestinal Smooth Muscles. 1955-1956
68 IP and IG Loads on Water Intake. 1986
68 Isoproterenol and Renin Sensitivity in Male and Female Rats. 1975-1976
68 Isoproterenol Drink in Estrogen-Treated Rats. 1977
68 Isoproterenol in Estrogen-Treated Rats. 1974-1976
68 Lesion and Renal-Encapsulated Rats. 1977-1978
68 Lighty, Jr., George W. 1968-1971
68 Low Sodium Diet Study. 1986-1987
68 Maltose Preference Threshold and Estrogen. 1985-1986
68 Methazolamide I131. 1963-1966
68 Methylphenidate on Spontaneous Activity. Not Dated
68 Mineralocorticoids on A-II Receptors. 1985-1986
68 Mineralocorticoids on NaCl Appetite. Not Dated
68 Miscellaneous Unmounted Graph Slides. Not Dated
68 Mineralocorticoids on NaCl Appetite. 1965-1966
68 NaCl Appetite of PTU-Treated Rats. 1961
68 NaCl Aversion of Hypertensive Rats. 1958-1959
68 Natriuretic Activity of Sydnone. 1964
68 Natriuretic Activity of Sydnones. Not Dated
68 Oral Contraceptive on Salt Appetite, Running Activity and Blood Pressure. Not Dated
68 Oral Contraceptive - Salt Appetite Tables. Circa 1974
68 Oral Contraceptives, Water Temperature on Post-Cold Drinking, Thermogenic Drinking in Rats, etc. Circa 1974
68 Osmolarity Experiments. 1967-1979
68 Osmoreceptor Mediation of Thirst. 1981
69 Phenylephrine and Norepinephrine on Tail Skin and Colonic Temperature (Rats). 1976
69 Physiological Responses to Cold - Cold Injury. 1950-1981
69 Plasma Osmolality and Flow Resistance. Not Dated
69 Post-Cold Drinking Response. 1965-1966
69 Post-Cold Drinking Response. Not Dated
69 Post-Cold Drinks (Sprague-Dawley). 1981-1989
69 Post-Cold Exposure Drinking (Na-Deficient Diet). Not Dated
69 Post-Hypoxic Drinking. Not Dated
69 Potassium Nitrate and Blood Pressure. Not Dated
69 Potassium Supplementation and Performance. Circa 1958
69 Prazosin and L-Arginine on Cold-Induced Hypertension. 1992-1994
69 PTU-Aldosterone-NaCl Appetite Angiotensin-DOCA. 1963
69 PTU and Salt Preference. Not Dated
69 PTU on Aldosterone Secretion. Not Dated
69 PTU and Hypertension. Circa 1958
69 PTU-NaCl Appetite Estrone Cortiosterone Renin. 1964-1965
69 PTU on Intake and Loss of Sodium. Not Dated
69 PTU Taste Threshold 1 and 2. Not Dated
69 PTU-Treated Rats - NaCl Intake, Effect of Angiotensin, Pitressin and Aldosterone. 1964-1965
69 Radioactive Iodine Treatment of Hypertension. Not Dated
69 Reduced Beta-Adrenergic Responsiveness in Rats. 1974
69 Relationship Between Blood Pressure and Organ Weight in Rats. 1961-1962
69 Renal-Hypertension (Lecture). 1959
69 Renal-Thyroid Interrelationships. Not Dated
69 Renin-Angiotensin-Aldosterone. 1958-1984
69 Research Ideas-Oral Contraceptives. 1972-1984
69 Responsiveness to Dipsogenic Stimuli in Rats. 1975-1976
69 Role of Adrenal Glands in Renal Hypertension. Not Dated
69 The Role of Salt in Cardiovascular Hypertension. 1981
69 Role of Thyroid Gland in Hypertension. Not Dated
69 Running Activity (Experiment on PTU-Treated Rats). Not Dated
69 Salivary Na Concentration and DOCA in Adrex Rats. 1964
69 Salt Appetite. 1959-1970
69 Salt Appetite of Adrenalectomized Rats. Circa 1958
69 Salt Appetite of Goitrogen-Treated Rats. Not Dated
69 Salt Appetite of Hypothyroid Rats. Not Dated
69 Salt in Diet Study. 1981
69 Saluretics in Hypertension. 1959-1963
69 Scientific Meetings. 1949-1961
69 Serotonin and Drinking. 1986-1987
69 Sodium and Potassium Exchange in Adrenalectomized Rats. 1968
69 Sodium and Potassium Exchange in Adrenalectomized Rats. Not Dated
69 Sodium Loss of PTU-Treated Rats. Not Dated
69 Spiperone and Hypertonic Saline-Induced Drinking. 1978-1980
69 Spironolactone on Salt Intake. Not Dated
69 Spontaneous Hypertensive Rats. 1973-1974
69 Strain Differences in Reference Threshold for NaCl. 1991
69 Study of Rat Vitals During Exposure to Cold. 1952-1958
69 Temperature Regulation. 1954-1963
69 Termination of Drinking: Satiation. 1981
69 Testosterone Experiments (Castrated and Intact Rats). 1978-1979
69 Thirst After Removal from Cold. 1970
69 Thirst in Hypertensive Rats. 1975
69 Thirst in Spontaneously Hypertensive Rats. 1976
69 Thyroid Activity of Hypertensive Rats. Not Dated
69 Thyroid and Antithyroid Activities, Thyroid Dressing Factor of Renal Origin. Not Dated
69 Thyroid and Hypertension. 1960
69 Thyroid and Metabolic Responses to Heat. 1966-1968
69 Thyroid Hypertension (Summary). 1969-1970
69 Thyroidectomized Female Rats. 1957-1958
69 Thyroidectomy, Adrenalectomy and Cold Exposure. Not Dated
69 Thyroidectomy and Hypertension. Not Dated
69 Tracing of Normal Thyroids and Adrenals. Not Dated
69 Tryptophan Analog Study. 1988-1990
69 University of Rochester. Not Dated
69 VO2 Apparatus. 1974
69 Water and Na in Hypothyroidism. Not Dated
69 Water Exchange in Hypothyroidism. 1961
69 Slides: Adrenal Cortex. Not Dated
69 Slides: Adrenal Cortex. Not Dated
69 Slides: Adrenal Cortex and Medulla. Not Dated
69 Slides: Adrenal Cortical. Not Dated
69 Slides: Adrenal Medulla. Not Dated
69 Slides: Appetite. Not Dated
69 Slides: Body Fluid Homeostasis. Not Dated
69 Slides: Female Sex Hormones. Not Dated
69 Slides: Gastrointestinal Tract. Not Dated
69 Slides: Growth Hormones. Not Dated
69 Slides: Hypertension. Not Dated
69 Slides: Intro Endocrine. Not Dated
69 Slides: Miscellaneous. Not Dated
69 Slides: Pancreas. Not Dated
69 Slides: Parathyroid Hormone. Not Dated
69 Slides: Regulation of E.C. and Blood Volume Osmoreceptors and Volume Receptors. Not Dated
69 Slides: Temperature Regulation. Not Dated
69 Slides: Testes, Testosterone. Not Dated
69 Slides: Thirst. Not Dated
69 Slides: Thyroid Gland. Not Dated
69 Slides: Water and Sodium Exchange in Thyroid Rats. Not Dated
70 Slides: Male Sex Hormones (16). Not Dated
70 Slides: Unidentified pertaining to Ovarian Hormone and Uterus of Female Rats (22) . Not Dated
70 Slides: Thyroid Slides Not Used (18). 1973
70 Slides: Adrenal Cortex Not Used (12). Not Dated
70 Slides: Temperature Regulation (23). Not Dated
71 Slides: Unidentified pertaining to Calcium and Phosphate Intake in Normal Rats (13). Not Dated
71 Slides: Unidentified pertaining to Blood Pressure and Rate of Flow (10) . Not Dated
71 Slides: Unidentified pertaining to NaCl and Food and Fluid Intake (10). Not Dated
71 Slides: Unidentified pertaining to Factors Affecting Size of Human Small Intestine (8). Not Dated
71 Slides: Unidentified pertaining to Rate of Plasma Flow in Normal Human Males (8). Not Dated
71 Slides: Unidentified pertaining to Thyroid of Lesioned Rats (5). Not Dated
71 Slides: Unidentified pertaining to Factors Affecting Gastric Motility in Humans (11). Not Dated
71 Slides: Unidentified pertaining to Role of Pituitary Growth Hormone in Humans (18). Not Dated
71 Slides: Unidentified pertaining to Adrenal, Thyroid and Pituitary Interactions (9). Not Dated


Patent and Financial Files 1987-1999

This series includes financial and legal material, as well as associated correspondence and news clippings, related to patents held by Fregly. The majority of the files pertain to the high-protein, milk-based beverage GO! and the thirst quencher beverage TQII (or, TQ2). The TQII beverage, invented by Fregly, J.R. Cade, and M. Privette, was the subject of law suits by Quaker Oats, which claimed that the beverage was too similar to Gatorade (also created by Cade and owned by Quaker). Rather than fight a costly court battle, the inventors sold the invention to Quaker, which had no plans to market it despite the assertion by the inventors that it was superior to Gatorade. In addition, the series includes a few files pertaining to Fregly's Tryptophan and L-5-Hydroxytryptophan hypertension treatment.


Box
72 Global Telemedia International (GO!). 1994-1995
72 GO!. 1989-1992
72 News Clippings - Cade, J. Robert. 1989-1999
72 News Clippings - Gatorade. 1991-1994
72 News Clippings - GO!. 1988-1992
72 News Clippings - TQII. 1990-1993
72 Phoenix Advanced Technology. 1988-1995
72 Phoenix Advanced Technology and Nutri-Products, Inc. 1988-1994
72 TQII (Folder 1 of 2). 1988-1993
72 TQII (Folder 2 of 2). 1988-1993
72 TQII - Gatorade Dispute (Phoenix Advanced Technology, Quaker Oats, Stokely-Van Camp). 1992-1995
72 TQII - Gatorade Dispute (Phoenix Advanced Technology, Quaker Oats, Stokely-Van Camp). 1992-1993
72 TQII - Gatorade Dispute (Phoenix Advanced Technology, Quaker Oats, Stokely-Van Camp). 1990-1992
72 TQII - Gatorade Dispute (Phoenix Advanced Technology, Quaker Oats, Stokely-Van Camp). 1989-1991
72 TQII - Gatorade Dispute (Phoenix Advanced Technology, Quaker Oats, Stokely-Van Camp). 1989-1991
72 TQII - Patents (Including Racer's Edge). 1990-1993
72 Tryptophan and L-5-Hydroxytryptophan Hypertension Treatment. 1989-1992
72 Tryptophan and L-5-Hydroxytryptophan Hypertension Treatment. 1992-1994
72 Tryptophan and L-5-Hydroxytryptophan Hypertension Treatment. 1992-1995
72 Tryptophan and L-5-Hydroxytryptophan Hypertension Treatment. 1987-1995
72 University of Florida Foundation (TQII and GO!). 1989-1995
72 Walnut Street Securities (Phoenix, Global Telemedia). 1993-1995


Personal and Miscellaneous 1943-2003

This small series includes biographical material on Fregly, family correspondence, awards and certificates, plaques, university transcripts, and miscellaneous memorabilia and artifacts. In addition, there are a few files containing material created by or related to his wife, Marilyn Fregly. Two of these files pertain to the American Civilization Seminar (previously known as the Arts and Civilization Seminar), an annual seminar series held at the University of Florida for several years. The memorabilia and artifacts include Fregly's U.S. Army identification tags, his academic hood, and the guest registers from his funeral service.


Box
72 Award and Certificates. 1968-1994
72 Biographical Material (Curriculum Vitae). 1996
72 Family and Personal Correspondence. 1943-1991
72 Inscribed Memories - Williams-Thomas Funeral Home (Guest Register for Fregly Services). 1996
72 Inscribed Memories - Williams-Thomas Funeral Home (Guest Register for Fregly Services). 1996
72 Marilyn Fregly - American Civilization Seminar - Correspondence and Membership Information. 1991-2003
72 Marilyn Fregly - American Civilization Seminar - Programs and Advertisements. 1989-2003
72 Marilyn Fregly - Writings and Correspondence (Articles Co-Authored with M.J. Fregly). 1978-1999
72 Transcripts - University of Rochester and Bucknell University. 1952
73 Plaque - Distinguished Faculty Award, University of Florida. 1982
73 Plaque - Award of Appreciation, Federation of American Societies for Experimental Biology (APS and LSRO). Circa 1985
73 Plaque - Recognition of Being One of the Founding Faculty of the Department of Physiology and Continuous Member for 36 Years. 1992
73 Plaque - Outstanding and Dedicated Service While Service as President, Society of the Sigma Xi, UF Chapter. 1977-1978
73 Photocopy of Photograph of Fregly (on dowel) Used During 40th High School Reunion. Not Dated
73 Name Plate for Fregly. Not Dated
73 Military Identification "Dog Tags" for Fregly. Not Dated
74 Academic Hood (Blue and Gold - Ph.D., Science). Not Dated
75 United States Flag - Used During Burial Services for Fregly. Not Dated


Computer Media

Includes floppy disks primarily containing research files, writings and correspondence. The disks primarily are 5 1/4" Mac format, although there are a handful of 2.5" disks.


Box
76 Computer Floppy Disks (5 1/4" and 2.5" IBM and Mac Format) - Research Data, Writings, Correspondence, etc. Not Dated


Selected Subjects and Access Terms

Cold -- Physiological effect.
Hypertension -- Endocrine aspects.
Hypertension -- Nutritional aspects.
Oral contraceptives -- Physiological effect.
Physiology -- Research.
Physiology -- Study and teaching.
Salt -- Physiological effect.
University of Florida. College of Medicine.
Water-electrolyte balance (Physiology)



For further information, please contact: Special Collections Access Services.

University of Florida Home Page